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Listar por autor "Jiménez-Pérez, Miguel"
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Clinical characteristics and outcome of drug-induced liver injury in the older patients: from the young-old to the oldest-old
Weersink, Rianne A.; Alvarez-Alvarez, Ismael; Medina-Caliz, Inmaculada; Sanabria-Cabrera, Judith Adriana
; Robles-Díaz, María Mercedes
; Ortega-Alonso, Aida; García-Cortés, Miren
; Bonilla, Elvira; Niu, Hao; Soriano, German; Jiménez-Pérez, Miguel
; Hallal, Hacibe; Blanco, Sonia; Kaplowitz, Neil; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
[et al.] (Wiley, 2020-11-11)
Old patients with hepatotoxicity have been scarcely studied in idiosyncratic drug-induced liver injury (DILI) cohorts. We sought for the distinctive characteristics of DILI in older patients across age groups. A total of ... -
Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry
Stephens, Camilla; Robles-Díaz, María Mercedes; Medina-Caliz, Inmaculada
; García-Cortés, Miren
; Ortega-Alonso, Aida; Sanabria-Cabrera, Judith Adriana
; González-Jiménez, Andrés; Alvarez-Alvarez, Ismael; Slim, Mahmoud; Jiménez-Pérez, Miguel
; Gonzalez-Grande, Rocio; Fernandez, M Carmen; Casado, Marta; Soriano, German; Roman, Eva; Hallal, Hacibe; Romero-Gomez, Manuel; Castiella, Agustin; Conde, Isabel; Prieto, Martin; Moreno-Planas, José María; Giraldez, Alvaro; Moreno-Sanfiel, J Miguel; Kaplowitz, Neil; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
[et al.] (Elsevier, 2021-02-01)
Background & aims: Prospective drug-induced liver injury (DILI) registries are important sources of information on idiosyncratic DILI. We aimed to present a comprehensive analysis of 843 patients with DILI enrolled into ... -
Experiencia en práctica clínica real de los nuevos Antivirales de Acción Directa en hepatitis crónica C
Pinazo Martinez, Isabel Leyre (UMA Editorial, 2017-10-02)La infección por el virus de la hepatitis C (VHC) es la principal causa de hepatitis crónica (HC), hasta en el 30 % de los casos se desarrollará cirrosis y en un 2 % carcinoma hepatocelular (CHC) (Gower et al, 2014). Pese ... -
Incidence and prevalence of acute hepatitis E virus infection in patients with suspected Drug-Induced Liver Injury in the Spanish DILI Registry
Sanabria-Cabrera, Judith Adriana; Sanjuan-Jimenez, Rocio; Clavijo-Frutos, Encarnación
; Medina-Caliz, Inmaculada
; González-Jiménez, Andrés; García-Cortés, Miren
; Ortega-Alonso, Aida; Jiménez-Pérez, Miguel
; Gonzalez-Grande, Rocio; Stephens, Camilla; Robles-Díaz, María Mercedes
; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
[et al.] (2020)
Background and Aims: Drug-induced liver injury (DILI) presents with a wide phenotypic spectrum requiring an extensive differential diagnosis. Hepatitis E virus (HEV) is not systematically ruled out during acute hepatitis ... -
Lymphocyte Profile and Immune Checkpoint Expression in Drug-Induced Liver Injury: An Immunophenotyping Study
Cueto-Sanchez, Alejandro; Niu, Hao; Del Campo-Herrera, Enrique; Robles-Díaz, María Mercedes; Sanabria-Cabrera, Judith Adriana
; Ortega-Alonso, Aida; García-Cortés, Miren
; Gonzalez-Grande, Rocio; Jiménez-Pérez, Miguel
; Ruiz-Cabello, Francisco; Andrade-Bellido, Raúl Jesús
; Lucena-González, María Isabel
[et al.] (Wiley, 2021-09-20)
The identification of specific HLA risk alleles in drug-induced liver injury (DILI) points toward an important role of the adaptive immune system in DILI development. In this study, we aimed to corroborate the role of an ... -
Microbiota diversity in nonalcoholic fatty liver disease and in drug-induced liver injury
Rodriguez-Diaz, Cristina; Taminiau, Bernard; García-García, Alberto; Cueto-Sanchez, Alejandro; Robles-Díaz, María Mercedes; Ortega-Alonso, Aida; Martín-Reyes, Flores; Daube, Georges; Sanabria-Cabrera, Judith Adriana
; Jiménez-Pérez, Miguel
; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
; García Fuentes, Eduardo; García-Cortés, Miren
[et al.] (Elsevier, 2022-08)
The gut microbiota could play a significant role in the progression of nonalcoholic fatty liver disease (NAFLD); however, its relevance in drug-induced liver injury (DILI) remains unexplored. Since the two hepatic disorders ...