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Mostrando ítems 1-18 de 18
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Characterization of drug-induced liver injury associated with drug reaction with eosinophilia and systemic symptoms in two prospective DILI registries
Medina-Cáliz, Inmaculada; Sanabria-Cabrera, Judith Adriana
; Villanueva-Paz, Marina; Aukštikalnė, Lauryna; Stephens, Camilla; Robles-Díaz, María Mercedes
; Pinazo-Bandera, José M.; García-Cortés, Miren
; Conde, Isabel; Soriano, German; Bessone, Fernando; Hernandez, Nelia; Nunes, Vinicius; Parana, Raymundo; Lucena-González, María Isabel
; Andrade, Raúl J.; Alvarez-Alvarez, Ismael; Niu, Hao[et al.] (Springer Nature, 2023-12-05)
Idiosyncratic drug-induced liver injury (DILI) associated with drug reactions with eosinophilia and systemic symptoms (DRESS) is poorly characterized among patients of Western countries. We aimed to comprehensively assess ... -
Clinical characteristics and outcome of drug-induced liver injury in the older patients: from the young-old to the oldest-old
Weersink, Rianne A.; Alvarez-Alvarez, Ismael; Medina-Cáliz, Inmaculada; Sanabria-Cabrera, Judith Adriana
; Robles-Díaz, María Mercedes
; Ortega-Alonso, Aida; García-Cortés, Miren
; Bonilla, Elvira; Niu, Hao; Soriano, German; Jiménez-Pérez, Miguel
; Hallal, Hacibe; Blanco, Sonia; Kaplowitz, Neil; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
[et al.] (Wiley, 2020-11-11)
Old patients with hepatotoxicity have been scarcely studied in idiosyncratic drug-induced liver injury (DILI) cohorts. We sought for the distinctive characteristics of DILI in older patients across age groups. A total of ... -
Clinical presentation, causative drugs and outcome of patients with autoimmune features in two prospective DILI registries
García-Cortés, Miren; Ortega-Alonso, Aida; Matilla-Cabello, Gonzalo; Medina-Cáliz, Inmaculada
; Castiella, Agustin; Conde, Isabel; Bonilla-Toyos, Elvira; Pinazo-Bandera, José M.; Hernandez, Nelia; Tagle, Martin; Nunes, Vinicius; Parana, Raymundo; Bessone, Fernando; Kaplowitz, Neil; Lucena-González, María Isabel
; Alvarez-Alvarez, Ismael; Robles-Díaz, María Mercedes
; Andrade-Bellido, Raúl Jesús
[et al.] (Wiley, 2023)
Background & aims: Idiosyncratic drug-induced liver injury (DILI) with autoimmune features is a liver condition with laboratory and histological characteristics similar to those of idiopathic autoimmune hepatitis (AIH), ... -
Colaboración sanitaria de la Universidad de Málaga en zonas marginales de Tegucigalpa.
Ledesma-Albarrán, Juana María; Cabello-Porras, María Rosario
; Rivera-Cuello, María de las Mercedes
; Medina-Cáliz, Inmaculada
(Universidad de Barcelona, 2023-01-25)
Una experiencia de Aprendizaje servicio (ApS) de la Facultad de Medicina de Málaga, se ha desarrollado en colaboración con la Organización No Gubernamental Asociación, Colaboración y Esfuerzo (ACOES) en Tegucigalpa. En ... -
Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry
Stephens, Camilla; Robles-Díaz, María Mercedes; Medina-Cáliz, Inmaculada
; García-Cortés, Miren
; Ortega-Alonso, Aida; Sanabria-Cabrera, Judith Adriana
; González-Jiménez, Andrés; Alvarez-Alvarez, Ismael; Slim, Mahmoud; Jiménez-Pérez, Miguel
; González-Grande, Rocío; Fernández, M. Carmen; Casado, Marta; Soriano, German; Roman, Eva; Hallal, Hacibe; Romero-Gomez, Manuel; Castiella, Agustin; Conde, Isabel; Prieto, Martin; Moreno-Planas, José María; Giraldez, Alvaro; Moreno-Sanfiel, J Miguel; Kaplowitz, Neil; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
[et al.] (Elsevier, 2021-02-01)
Background & aims: Prospective drug-induced liver injury (DILI) registries are important sources of information on idiosyncratic DILI. We aimed to present a comprehensive analysis of 843 patients with DILI enrolled into ... -
Critical Review of Gaps in the Diagnosis and Management of Drug-Induced Liver Injury Associated with Severe Cutaneous Adverse Reactions
Villanueva-Paz, Marina; Niu, Hao; Segovia-Zafra, Antonio; Medina-Cáliz, Inmaculada; Sanabria-Cabrera, Judith Adriana
; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
; Alvarez-Alvarez, Ismael; Sanabria-Cabrera, Judith Adriana
[et al.] (MDPI, 2021-11-15)
Drug-induced liver injury (DILI) encompasses the unexpected damage that drugs can cause to the liver. DILI may develop in the context of an immunoallergic syndrome with cutaneous manifes- tations, which are sometimes severe ... -
Hepatic safety of atypical antipsychotics: current evidence and future directions
Slim, Mahmoud; Medina-Cáliz, Inmaculada; González-Jiménez, Andrés; Cabello-Porras, María Rosario
; Mayoral Cleries, Fermín; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
[et al.] (Springer, ADIS INT LTD, 2016-10)
The newer atypical antipsychotic agents (AAPs) represent an attractive therapeutic option for a wide range of psychotic disorders, including schizophrenia and bipolar mania, because of the reduced risk of disabling ... -
Herbal and dietary supplement-induced liver injuries in the spanish DILI registry
Medina-Cáliz, Inmaculada; García-Cortés, Miren
; González-Jiménez, Andrés; Cabello-Porras, María Rosario
; Robles-Díaz, María Mercedes
; Sanabria-Cabrera, Judith Adriana
; Sanjuan-Jimenez, Rocio; Ortega-Alonso, Aida; García-Muñoz, Beatriz; Moreno, Inmaculada; Jiménez-Pérez, Miguel
; Fernández, M. Carmen; Ginés, Pere; Prieto, Martin; Conde, Isabel; Hallal, Hacibe; Soriano, German; Roman, Eva; Castiella, Agustin; Blanco-Reina, Encarnación
; Montes, Maria R; Quiros-Cano, Marta; Martín-Reyes, Flores; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
[et al.] (Elsevier, 2018-01)
There have been increasing reports of liver injury associated with use of herbal and dietary supplements.We collected and analyzed data on demographic and clinical features, along with biochemical parameters, of 32 patients ... -
Herbal and dietary supplements-induced liver injury in Latin America: Experience from the LATINDILI Network
Bessone, Fernando; García-Cortés, Miren; Medina-Cáliz, Inmaculada
; Hernandez, Nelia; Parana, Raymundo; Mendizabal, Manuel; Schinoni, María I.; Ridruejo, Ezequiel; Nunes, Vinicius; Peralta, Mirta; Santos, Genario; Anders, Margarita; Chiodi, Daniela; Tagle, Martin; Montes, Pedro; Carrera, Enrique; Arrese, Marco; Lizarzabal, M. Isabel; Alvarez-Alvarez, Ismael; Caballano-Infantes, Estefanía; Niu, Hao; Pinazo, Jose; Cabello-Porras, María Rosario
; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
[et al.] (Elsevier, 2022)
Background: Herbal and dietary supplements (HDS) consumption, a growing cause of hepatotoxicity, is a common practice among Latin-American populations. Objectives: To evaluate clinical, laboratory features and outcome ... -
Incidence and prevalence of acute hepatitis E virus infection in patients with suspected Drug-Induced Liver Injury in the Spanish DILI Registry
Sanabria-Cabrera, Judith Adriana; Sanjuan-Jimenez, Rocio; Clavijo-Frutos, Encarnación
; Medina-Cáliz, Inmaculada
; González-Jiménez, Andrés; García-Cortés, Miren
; Ortega-Alonso, Aida; Jiménez-Pérez, Miguel
; González-Grande, Rocío; Stephens, Camilla; Robles-Díaz, María Mercedes
; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
[et al.] (2020)
Background and Aims: Drug-induced liver injury (DILI) presents with a wide phenotypic spectrum requiring an extensive differential diagnosis. Hepatitis E virus (HEV) is not systematically ruled out during acute hepatitis ... -
Nitrofurantoin‑induced liver injury: long‑term follow‑up in two prospective DILI registries
Bessone, Fernando; Ferrari, Antonella; Hernandez, Nelia; Mendizabal, Manuel; Zerega, Alina; Tanno, Federico; Reggiardo, Maria Virginia; Vorobioff, Julio; Tanno, Hugo; Arrese, Marco; Nunes, Vinicius; Tagle, Martin; Medina-Cáliz, Inmaculada; Robles‑Diaz, Mercedes; Niu, Hao; Alvarez-Alvarez, Ismael; Stephens, Camilla; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
[et al.] (Springer Nature, 2022-11-22)
Nitrofurantoin is a synthetic antibiotic that is recommended as first-choice treatment for uncomplicated urinary tract infections. The prescription of this drug has increased dramatically, especially in Latin American ... -
Potential benefit and lack of serious risk from corticosteroids in drug-induced liver injury: an international, multicentre, propensity score-matched analysis
Niu, Hao; Ma, Jiayi; Medina-Cáliz, Inmaculada; Robles-Díaz, María Mercedes
; Bonilla-Toyos, Elvira; Ghabril, Marwan; Lucena-González, María Isabel
; Alvarez-Alvarez, Ismael; Andrade-Bellido, Raúl Jesús
[et al.] (Wiley, 2022-12-22)
Background: The use of corticosteroids to treat patients with idiosyncratic drug-induced liver injury (DILI) relies on empirical clinical decisions. Aim: To investigate the relationship between corticosteroids and ... -
Prior drug allergies are associated with worse outcome in patients with idiosyncratic drug-induced liver injury: A machine learning approach for risk stratification
Niu, Hao; Solis-Muñoz, Pablo; García-Cortés, Miren; Sanabria-Cabrera, Judith Adriana
; Robles-Díaz, María Mercedes
; Romero-Flores, Rocío; Bonilla-Toyos, Elvira; Ortega-Alonso, Aida; Pinazo-Bandera, José M.; Cabello-Porras, María Rosario
; Bessone, Fernando; Hernandez, Nelia; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
; Medina-Cáliz, Inmaculada
; Alvarez-Alvarez, Ismael[et al.] (Elsevier, 2023-12-08)
The impact of prior drug allergies (PDA) on the clinical features and outcomes of patients who develop idiosyncratic drug-induced liver injury (DILI) is largely unknown. We aimed to assess the clinical presentation and ... -
Profile of herbal and dietary supplements induced liver injury in Latin America: A systematic review of published reports
Santos, Genario; Gasca, Jessica; Parana, Raymundo; Nunes, Vinicius; Schinnoni, Maria; Medina-Cáliz, Inmaculada; Cabello-Porras, María Rosario
; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
[et al.] (WILEY, 2020-06)
Hepatotoxicity related to HDS is a growing global health issue. We have undertaken a systematic review of published case reports and case series from LA from 1976 to 2020 to describe the clinical features of HDS related ... -
Rechallenge in idiosyncratic drug-induced liver injury: An analysis of cases in two large prospective registries according to existing definitions
Pinazo-Bandera, José M.; Niu, Hao; Alvarez-Alvarez, Ismael; Medina-Cáliz, Inmaculada; Del Campo-Herrera, Enrique; Ortega-Alonso, Aida; Robles-Díaz, María Mercedes
; Hernandez, Nelia; Parana, Raymundo; Nunes, Vinicius; Girala, M.; Bessone, Fernando; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
; García-Cortés, Miren
[et al.] (Elsevier, 2024-05)
Los datos sobre la reexposición positiva en la lesión hepática inducida por fármacos (DILI) idiosincrásica son escasos. Apuntamos a analizar la presentación clínica, el resultado y los fármacos asociados con la reexposición ... -
Serious liver injury induced by Nimesulide: an international collaboration study reporting 57 cases
Bessone, Fernando; Hernandez, Nelia; Mendizabal, Manuel; Ridruejo, Ezequiel; Gualano, Gisela; Fassio, Eduardo; Peralta, Mirta; Fainboim, Hugo; Anders, Margarita; Tanno, Hugo; Tanno, Federico; Parana, Raymundo; Medina-Cáliz, Inmaculada; Robles-Díaz, María Mercedes
; Alvarez-Alvarez, Ismael; Niu, Hao; Stephens, Camilla; Colombato, Luis; Arrese, Marco; Reggiardo, Maria Virginia; Ono, Suzane Kioko; Carrilho, Flair; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
[et al.] (Springer, 2021-03-24)
Nimesulide is a non-steroidal anti-inflammatory drug still marketed in many countries. We aim to analyze the clinical phenotype, outcome, and histological features of nimesulide-induced liver injury (nimesulide-DILI). We ... -
Therapeutic management of idiosyncratic drug‑induced liver injury and acetaminophen hepatotoxicity in the paediatric population: a systematic review.
Niu, Hao; Atallah, Edmond; Alvarez-Alvarez, Ismael; Medina-Cáliz, Inmaculada; Aithal, Guruprasad P.; Arikan, Cigdem; Andrade-Bellido, Raúl Jesús
; Lucena-González, María Isabel
[et al.] (Springer Nature, 2022)
Introduction: Drug-induced liver injury (DILI) is a rare but serious adverse event that can progress to acute liver failure (ALF). The evidence for treatment of DILI in children is scarce. Objective: We aim to comprehensively ... -
Underuse of indicated medications in elderly
Blanco-Reina, Encarnación; Ariza-Zafra, Gabriel; Ocaña-Riola, Ricardo; Medina-Cáliz, Inmaculada
; Márquez, Elisa I.; Bellido-Estévez, Inmaculada
[et al.] (2015-07-23)
Introduction: Treatment omissions are very important to value the quality of pharmacological therapy. In fact, suboptimal prescribing has been defined as overuse (polypharmacy), inappropriate prescribing (drug whose risks ...