Listar por autor "Cubero, Francisco Javier"
Mostrando ítems 1-3 de 3
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Biomarkers of idiosyncratic drug-induced liver injury (DILI) - a systematic review
(Taylor & Francis, 2021-11-15)Introduction: Idiosyncratic drug-induced liver injury (DILI) is an unpredictable event, and there are no specific biomarkers that can distinguish DILI from alternative explanations or predict its clinical outcomes. Areas ... -
Methionine Cycle Rewiring by Targeting miR-873-5p Modulates Ammonia Metabolism to Protect the Liver from Acetaminophen
Rodríguez-Agudo, Rubén; Goikoetxea-Usandizaga, Naroa; Serrano-Maciá, Marina; Fernández-Tussy, Pablo; Fernández-Ramos, David; Lachiondo-Ortega, Sofía; González-Recio, Irene; Gil-Pitarch, Clàudia; Mercado-Gómez, María; Bizkarguenaga, Maider; Lopitz-Otsoa, Fernando; Petrov, Petar; Bravo, Miren; Martijn Van Liempd, Sebastiaan; Falcon-Perez, Juan Manuel; Zabala-Letona, Amaia; Carracedo, Arkaitz; Vicente Castell, Jose; Jover, Ramiro; Martínez-Cruz, Luis Alfonso; Cardoso Delgado, Teresa; Cubero, Francisco Javier; Lucena-González, María Isabel
; Andrade-Bellido, Raul Jesus; Mabe, Jon; Simón, Jorge; Martínez-Chantar, María Luz[et al.] (IOAP-MPDI, 2022-04-30)
Drug-induced liver injury (DILI) development is commonly associated with acetaminophen (APAP) overdose, where glutathione scavenging leads to mitochondrial dysfunction and hepatocyte death. DILI is a severe disorder without ... -
Oxidative Stress in Drug-Induced Liver Injury (DILI): From Mechanisms to Biomarkers for Use in Clinical Practice
Villanueva-Paz, Marina; Morán, Laura; Lopez-Alcantara, Nuria; Freixo, Cristiana; Andrade-Bellido, Raul Jesus; Lucena-González, María Isabel; Cubero, Francisco Javier[et al.] (MDPI, 2021-03-05)
Idiosyncratic drug-induced liver injury (DILI) is a type of hepatic injury caused by an uncommon drug adverse reaction that can develop to conditions spanning from asymptomatic liver laboratoryabnormalitiestoacuteliverfa ...