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Desarrollo del epéndimo y subepéndimo en modelos animales en condiciones normales y en la hidrocefalia congénita
Rodriguez-Perez, Luis Manuel(Servicio de Publicaciones y Divulgacion Cientifica, 2016)
La presente Tesis Doctoral se ha diseñado para responder a las siguientes hipótesis: 1.- El programa de diferenciación de la zona ventricular que se afecta en el ratón hyh pone de manifiesto que la población celular que ... -
Gastrointestinal cancer: Relationship between histology and microbiota
García Sanz, A; Escamilla-Sanchez, Alejandro; Mercado-Saenz, Silvia
; Rodriguez-Perez, Luis Manuel
; Arranz-Salas, Isabel Maria
; Sanchez-Varo, Raquel Maria
; Pelaez-Gonzalez, Alberto Carlos
; Lopez-Villodres, Juan Antonio
; Bermudez-Flores, Diego Teofilo
[et al.] (2022-09-09)
Objectives: Review of the published literature concerning the relationship between microbiome and gastrointestinal cancer. Methods: Present work is focused on systematic research in the most prominent biomedical databases ... -
Gastrointestinal Stromal Tumor (GIST) and its relationship with germline mutations
Arranz-Salas, Isabel Maria; Jiménez-Campillo, Marta; Hierro-Martin, Maria Isabel
; Ortega-Jimenez, Maria Victoria
; Mercado-Saenz, Silvia
; Rodriguez-Perez, Luis Manuel
; Sanchez-Varo, Raquel Maria
; Escamilla-Sanchez, Alejandro
; Pelaez-Gonzalez, Alberto Carlos
; Bermudez-Flores, Diego Teofilo
[et al.] (2022)
We present the case of a 38-year-old man with a history of abdominal paraganglioma 10 years ago, who consulted for hematemesis and asthenia of 5 days' evolution. An upper gastrointestinal endoscopy was performed where a ... -
IPSC differentiation into ependymal progenitors to treat ventricular damage during hydrocephalus
Introduction: During both obstructive congenital hydrocephalus and post-hemorrhagic hydrocephalus additional pathological events are intimately associated with their ethiology: a) a detrimental inflammatory response; b) ... -
iPSC differentiation into ependymal progenitors to treat ventricular damage during hydrocephalus
Rodriguez-Perez, Luis Manuel; Hidalgo-Díaz, Juan Antonio; Jimenez-Lara, Antonio Jesus
; Paez-Gonzalez, Patricia
(2019-07-03)
Introduction: During both obstructive congenital hydrocephalus and post-hemorrhagic hydrocephalus additional pathological events are intimately associated with their ethiology: a) a detrimental inflammatory response; b) ... -
NG2 cells in an animal model of congenital hydrocephalus
Jimenez-Lara, Antonio Jesus; Ojeda-Pérez, Betsaida; García-Bonilla, María; Ruz-Maldonado, Inmaculada; Mateos-Grondona, Jesús
; Rodriguez-Perez, Luis Manuel
; Paez-Gonzalez, Patricia
[et al.] (2017-06-28)
NG2 cells are considered oligodendrocyte precursor cells (OPC). In pathological conditions, NG2 cells contribute to generate oligodendrocytes and reactive astrocytes. This study has been designed to uncover the role of NG2 ... -
Oligodendrocyte metabolism throughout its differentiation: immunocytochemistry study and its impact in remyelination
Gismero Rodríguez, Javier; Lopez-Villodres, Juan Antonio; Escamilla-Sanchez, Alejandro
; García Díaz, Beatriz; Rodriguez-Perez, Luis Manuel
; Mercado-Saenz, Silvia
; Ortega-Jimenez, Maria Victoria
; Arranz-Salas, Isabel Maria
; Pelaez-Gonzalez, Alberto Carlos
; Bermudez-Flores, Diego Teofilo
[et al.] (2022-09-07)
Introduction: Oligodendrocytes (OL) role in demyelinating pathologies such as multiple sclerosis and other neurodegenerative diseases is only recently being subject of extensive research. While the genetic and molecular ... -
Protein homeostasis as a therapeutical target for Alzheimer’s disease: analysis in the hippocampus of transgenic mouse models
Sanchez-Varo, Raquel Maria; Criado-Álamo, Elena; Fernández-Valenzuela, Juan Jose; Mercado-Saenz, Silvia
; Lopez-Villodres, Juan Antonio
; Escamilla-Sanchez, Alejandro
; Rodriguez-Perez, Luis Manuel
; Arranz-Salas, Isabel Maria
; Ortega-Jimenez, Concepcion
; Alba-Tercedor, Carmen; Gutierrez-Perez, Antonia
[et al.] (2022-09)
Alzheimer's disease (AD) constitutes the most prevalent form of dementia. There is no cure so there is an urgent need of novel therapeutic targets and treatments. The main histopathological hallmarks of AD brains are ...