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Listar por autor "Romero Zerbo, Silvana Yanina"
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Chronic cocaine exposure during adolescence in mice induces alterations in hippocampal neurogenesis and spatial memory
Gil Rodríguez, Sara; Mañas Padilla, María del Carmen; Berdugo-Gómez, Mario; Ávila-Gámiz, Fabiola; Romero Zerbo, Silvana Yanina; García-Fernández, Maria Inmaculada
; Santin-Nuñez, Luis Javier
[et al.] (2022-07)
Objectives: Cocaine is the second most widely consumed illicit drug even at early ages, with a prevalence of 2.9% in Spain in the 14-18 age group. Chronic consumption produces several cognitive-behavioral and hippocampal ... -
Insulin-like growth factor II neuroprotective effects against mitochondrial-oxidative and neuronal damage induced by CORT and MPP+ in dopaminergic neurons
Claros-Gil, Silvia; Cabrera, Pablo; Valverde, Nadia; Romero Zerbo, Silvana Yanina
; Lara, Estrella; López-González, Manuel Víctor
; Shumilov, Kirill; Rivera-Ramirez, Alicia
; Pavia-Molina, Jose
; Martin-Montañez, Elisa
; García-Fernández, Maria Inmaculada
[et al.] (2022-07-12)
Aims: Parkinson’s disease (PD) affects 1–3% of the population aged over 65. Stress seems to contribute to PD neuropathology, probably by dysregulation of the hypothalamic–pituitary–adrenal axis. Key factors are oxidative ... -
Neuroprotective effects of insulin-like growth factor II in a mouse model of Parkinson's disease
Ladrón de Guevara-Miranda, David; Martin-Montañez, Elisa; Valverde, Nadia; Lara, Estrella; Romero Zerbo, Silvana Yanina
; Millon-Peñuela, Carmelo
; Boraldi, Federica; Ávila-Gámiz, Fabiola; Pérez-Cano, Ana María; Garrido-Gil, Pablo; Labandeira-García, José Luis; Santin-Nuñez, Luis Javier
; Pavia-Molina, Jose
; García-Fernández, Maria Inmaculada
[et al.] (2022-07-20)
Progressive degeneration of the nigrostriatal dopaminergic pathway is a core, currently irreversible pathological hallmark of Parkinson’s disease (PD) that leads to a variety of motor and non-motor symptoms. Here, we aimed ... -
Role of Insulin-Growth Factor II on mitochondrial recovery in a cellular model of Parkinson's Disease
Valverde, Nadia; Romero Zerbo, Silvana Yanina; Lara, Estrella; Claros-Gil, Silvia
; Pavia-Molina, Jose
; Martin-Montañez, Elisa
; García-Fernández, Maria Inmaculada
[et al.] (Journal of Physiology and Biochemistry, 2022-09)
Insulin-growth factor II (IGF-II) has shown antioxidant and neuroprotective effects in some neurodegenerative disorders. ROS causes damage to cellular macromolecules affecting several cellular processes and resulting in ...