Listar por autor "Del Rio, Juan Carlos"
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Extracellular amyloid-beta and cytotoxic glial activation induce significant entorhinal neuron loss in young PS1(M146L)/APP(751SL) mice.
Moreno-González, Inés; Baglietto-Vargas, David; Sánchez-Varo, Raquel María
; Jiménez, Sebastián; Trujillo-Estrada, Laura Isabel; Sánchez-Mejías, Elisabeth; Del Rio, Juan Carlos; Torres, Manuel; Romero-Acebal, Manuel; Ruano, Diego; Vizuete, María Luisa; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia[et al.] (Sage, 2009-11-12)
Here we demonstrated that extracellular, not intracellular, Aβ and the associated cytotoxic glial neuroinflammatory response are major contributors of early neuronal loss in a PS1xAPP model. A significant loss of principal ...