Listar por autor "Suárez-Pérez, Juan"
Mostrando ítems 1-20 de 32
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Antipsychotic Medication Influences the Discriminative Value of Acylethanolamides as Biomarkers of Substance Use Disorder.
Herrera-Imbroda, Jesús; Flores-López, María; Requena-Ocaña, Nerea; Araos Gómez, Pedro Fernando; Ropero, Jessica; García-Marchena, Nuria; Bordallo Aragón, Antonio; Suárez-Pérez, Juan
; Pavón-Morón, Francisco Javier; Serrano, Antonia; Mayoral Cleries, Fermín; Rodriguez-de-Fonseca, Fernando[et al.] (MDPI, 2023-05-27)
Plasma acylethanolamides (NAEs), including the endocannabinoid anandamide (AEA), have been proposed as circulating biomarkers of substance use disorders. However, the concentration of these lipid transmitters might be ... -
Attenuation of cocaine-induced conditioned locomotion is associated with altered expression of hippocampal glutamate receptors in mice lacking LPA1 receptors.
Blanco-Calvo, Eduardo; Bilbao, Ainhoa; Luque-Rojas, María Jesús; Palomino, Ana; Bermúdez Silva, Francisco Javier; Suárez-Pérez, Juan; Santín-Núñez, Luis Javier; Estivill-Torrús, Guillermo; Gutiérrez-Pérez, Antonia; Campos-Sandoval, José A.; Márquez-Gómez, Javier; Rodriguez-de-Fonseca, Fernando[et al.] (Springer, 2012)
Lysophosphatidic acid is a phospholipid mediator that modulates neurodevelopment and neurogenesis in the hippocampus through its actions on LPA1 receptors. Emerging evidences support LPA1 as a mediator of learning and ... -
Behavioral traits predicting cocaine-conditioned place reference in mice: role of anxiety adn the basolateral amygdala
Ladrón de Guevara-Miranda, David; Pavón-Morón, Francisco Javier; Serrano, Antonia; Rivera, Patricia; Estivill-Torrús, Guillermo; Suárez-Pérez, Juan; Rodriguez-de-Fonseca, Fernando; Santín-Núñez, Luis Javier; Castilla-Ortega, María Estela[et al.] (2016-07-13)
Aims. The individual susceptibility to cocaine addiction, a factor of interest in the understanding and prevention of this disorder, may be predicted by certain behavioral traits. However, these are not usually taken into ... -
Bioética y legislación aplicada en Ciencias de la Salud.
Martín-Martín, Jaime; Santos-Amaya, Ignacio Miguel; Martín-de-las-Heras, Stella; Gaitán Arroyo, María Jesús; Suárez-Pérez, Juan; Rubio-Lamia, Leticia Olga[et al.] (Universidad de Málaga, 2023)
El presente manual titulado Bioética y Legislación Aplicada en Ciencias de la Salud ha sido realizado en base al material docente que se imparte al alumnado de la Facultad de Ciencias de la Salud (Grados de Enfermería, ... -
Cannabidiol administration during pregnancy and lactation modulates the suppressive effect of maternal alcohol exposure on cell proliferation and survival in the hippocampus of offspring
Rodríguez-Pozo, Miguel; Rubio-Rodríguez, Pablo; Rodríguez de Fonseca, Fernando; Suárez-Pérez, Juan; Rivera, Patricia (2024-11-28)
Excessive alcohol consumption during pregnancy causes neurodevelopmental disorders due to vulnerability and neuroadaptation of the immature brain with serious consequences on cognition. Since the endocannabinoid system ... -
Chronic ethanol induces morpohological changes on hippocampal microglia, which are reverted by pharmacological blockade of faah with urb597
Fernández-Arjona, María del Mar; Rivera, Patricia; Silva-Peña, Daniel; Blanco, Eduardo; Vargas, Antonio; López-Ávalos, María Dolores; Mateos-Grondona, Jesús; Serrano, Antonia; Pavón-Morón, Francisco Javier; Rodriguez-de-Fonseca, Fernando; Suárez-Pérez, Juan[et al.] (2018-11-29)
Here, we evaluated the pharmacological effects of fatty-acid amide-hydrolase (FAAH) inhibitor URB597 (0.3 mg/kg), oleoylethanolamide (OEA, 10 mg/kg), arachidonoylethanolamide (AEA, 10 mg/kg), the CB1 receptor agonist ACEA ... -
Clinical Value of Inflammatory and Neurotrophic Biomarkers in Bipolar Disorder: A Systematic Review and Meta-Analysis
Vega-Núñez, Amanda; Gómez-Sánchez-Lafuente, Carlos; Mayoral Cleries, Fermín; Bordallo Aragón, Antonio; Rodriguez-de-Fonseca, Fernando; Suárez-Pérez, Juan[et al.] (IOAP-MPDI, 2022-06-09)
Bipolar disorder (BD) is a multifactorial chronic psychiatric disease highly defined by genetic, clinical, environmental and social risk factors. The present systematic review and meta-analysis aimed to examine the ... -
Comorbidities and autopsy findings of COVID-19 deaths and their association with time to death: a systematic review and meta-analysis
Martín-Martín, Jaime; Martín-Cazorla, Fernando; Suárez-Pérez, Juan; Rubio-Lamia, Leticia Olga; Martín-de-las-Heras, Stella (2022-05)
Objective: Examination of postmortem findings can help establish effective therapeutic strategies to reduce mortality. The aim of this study was therefore to review complete autopsy cases and their postmortem findings and ... -
Dental color measurement to estimate age in adults: a systematic review and meta‑analysis
Martín-Martín, Jaime; Santos-Amaya, Ignacio Miguel; Gaitán‑Arroyo, María J.; Suárez-Pérez, Juan; Rubio-Lamia, Leticia Olga; Martin-de-las-Heras, Stella[et al.] (Springer Nature, 2024-03-08)
Age estimation is a major challenge in anthropology and forensic odontology laboratories, as well as in judicial settings, as one of the tools used in human identification. The aim of this study was to evaluate the usefulness ... -
Dietary administration of D-chiro-inositol attenuates sex-specific metabolic imbalances in the 5xFAD mouse model of Alzheimer’s disease
López-Gambero, Antonio J.; Pacheco-Sánchez, Beatriz; Rosell-del-Valle, Cristina; Medina-Vera, Dina; Navarro, Juan Antonio; Fernández-Arjona, María del Mar; De Ceglia, Marialuisa; Sanjuán-Solís, Jesús Carlos; Simon, Vincent; Cota, Daniela; Rivera, Patricia; Rodriguez-de-Fonseca, Fernando; Suárez-Pérez, Juan[et al.] (Elsevier, 2022-06)
Increasing evidence shows that hypothalamic dysfunction, insulin resistance, and weight loss precede and progress along with the cognitive decline in sporadic Alzheimer’s Disease (AD) with sex differences. This study aimed ... -
Early maternal deprivation induces gender-dependent changes on the expression of hippocampal CB(1) and CB(2) cannabinoid receptors of neonatal rats.
Suárez-Pérez, Juan; Llorente, Ricardo; Romero-Zerbo, Silvana Yanina; Mateos, Beatriz; Bermúdez Silva, Francisco Javier; Rodriguez-de-Fonseca, Fernando; Paz Viveros, Maria; Suárez-Pérez, Juan[et al.] (Wiley, 2009)
Early maternal deprivation (MD) in rats (24 h, postnatal day 9–10) is a model for neurodevelopmental stress. There are some data proving that MD affects the endocannabinoid system (ECS) in a gender-dependent manner, and ... -
Efecto del tratamiento antidepresivo fluoxetina sobre la microglía en regiones del sistema corticolímbico en un modelo preclínico de autoadministración de alcohol, fase de abstinencia y recaída
(UMA Editorial, 2023-03-02)Estado actual y justificación de la tesis: El alto consumo de alcohol (abuso y dependencia), principalmente en la población joven, y su alta comorbilidad con trastornos ansiosos-depresivos y su ulterior asociación con ... -
Estudio de la eficacia de la administración dietética del D-Chiro-inositol en la señalización de insulina, neuroinflamación y alteraciones metabólicas en un modelo animal de la enfermedad de Alzheimer
(UMA Editorial, 2023-03-02)La enfermedad de Alzheimer (EA) es un trastorno con un origen mayoritariamente esporádico caracterizado por el deterioro de la memoria, razonamiento y lenguaje, que conduce a la muerte pocos años después del diagnóstico. ... -
Instruments to measure skills and knowledge of physicians and medical students in palliative care: a systematic review of psychometric properties.
López García, Mónica; Rubio-Lamia, Leticia Olga; Martín-de-las-Heras, Stella; Suárez-Pérez, Juan; Pérez Cárceles, María Dolores; Martín-Martín, Jaime[et al.] (Taylor & Francis, 2022)
Purpose: Palliative care is constantly increasing around the world. The knowledge and skills of future physicians in this area are crucial. This study evaluates the psychometric properties of knowledge and skills questionnaires ... -
LH-21, a CB1 antagonist, reduces hepatotoxic damage produced by paracetamol overdose in a mice model.
Rodríguez-Pozo, Miguel; Gavito, Ana Luisa; Jagerovic, Nadine; Rodriguez-de-Fonseca, Fernando; Suárez-Pérez, Juan; Rivera, Patricia; Decara, Juan[et al.] (2023)
Drug-induced liver injury (DILI) is one of the main causes of hepatic acute failure. Paracetamol can cause it when is ingested in excessive doses, leading to the depletion of the antioxidant mechanisms of the hepatocytes ... -
Neuroplastic and cognitive impairment in substance use disorders: a therapeutic potential of cognitive stimulation
Sampedro-Piquero, Patricia; Ladrón de Guevara-Miranda, David; Pavón-Morón, Francisco Javier; Serrano, Antonia; Suárez-Pérez, Juan; Rodriguez-de-Fonseca, Fernando; Santín-Núñez, Luis Javier; Castilla-Ortega, María Estela[et al.] (Elsevier, 2019)
Drug addiction is a chronic and relapsing disorder in which repeated drug exposure compromises brain neuroplasticity. Brain areas normally involved in learning and goal- directed behaviors become corrupted, which may lead ... -
Overexpression of Cannabinoid CB2 Receptor in the Brain Induces Hyperglycaemia and a Lean Phenotype in Adult Mice
Romero-Zerbo, Silvana Yanina; Garcia-Gutierrez, M S; Suárez-Pérez, Juan; Rivera, Patricia; Ruz-Maldonado, Inmaculada; Vida, M.; Rodriguez-de-Fonseca, Fernando; Manzanares, Jorge; Bermúdez Silva, Francisco Javier[et al.] (Blackwell Publishing Ltd, 2009)
t is well known that the endocannabinoid system, through cannabinoid CB1 receptor activation,has an important role in the main aspects of energy balance (i.e. food intake, energy expenditureand glucose and fat metabolism), ... -
Partners in postmortem interval estimation: X-ray diffraction and Fourier transform spectroscopy
Rubio-Lamia, Leticia Olga; Suárez-Pérez, Juan; Martín-de-las-Heras, Stella; Zapico, Sara C. (MDPI, 2023-04-05)
The postmortem interval (PMI) is difficult to estimate in later stages of decomposition. There is therefore a need to develop reliable methodologies to estimate late PMI. This study aims to assess whether there is a ... -
Pharmacotherapeutic value of inflammatory and neurotrophic biomarkers in bipolar disorder: A systematic review
Ruiz-Sastre, Paloma; Gómez-Sánchez-Lafuente, Carlos; Martín-Martín, Jaime; Herrera-Imbroda, Jesús; Mayoral Cleries, Fermín; Santos-Amaya, Ignacio Miguel; Rodriguez-de-Fonseca, Fernando; Guzmán-Parra, José; Rivera, Patricia; Suárez-Pérez, Juan[et al.] (Elsevier, 2024-06-13)
Background: The various pharmacological interventions, ranging from mood stabilizers and antipsychotics to antidepressants, reflect the diff/iculty of treating depressive/manic symptomatology of bipolar disorder (BD). Among ... -
Plasma Concentrations of High Mobility Group Box 1 Proteins and Soluble Receptors for Advanced Glycation End-Products Are Relevant Biomarkers of Cognitive Impairment in Alcohol Use Disorder: A Pilot Study.
Rodriguez-de-Fonseca, Fernando; Medina-Paz, Francisco; Sapozhnikov, Mira; Hurtado-Guerrero, Isaac; Rubio-Lamia, Leticia Olga; Martín-de-las-Heras, Stella; Requena-Ocaña, Nerea; Flores-López, María; Fernández-Arjona, María del Mar; Rivera, Patricia; Serrano, Antonia; Serrano-Castro, Pedro Jesús; Zapico, Sara C.; Suárez-Pérez, Juan[et al.] (MDPI (Toxics), 2024)
Alcohol use disorder (AUD) is a major component in the etiology of cognitive decline and dementia. Underlying mechanisms by which long-term alcohol abuse causes cognitive dysfunction include excessive oxidative stress and ...