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Anticlusterin treatment of breast cancer cells increases the sensitivities of chemotherapy and tamoxifen and counteracts the inhibitory action of dexamethasone on chemotherapy-induced cytotoxicity
Redondo-Bautista, Maximino; Téllez-Santana, Teresa; Roldán Cardenete, María José; Serrano-Garballo, Alfonso; García Aranda, Marilina; Gleave, Martin E; Hortas Nieto, María Luisa; Morell Ocaña, Miguel[et al.] (BMC Springer Nature, 2007-12-13)Introduction: Overexpression of the apoptosis-related protein clusterin is associated with breast cancer development and tumor progression. We describe the use of clusterin-specific antisense oligonucleotides and antibodies ... -
Calcium Homeostasis in the Development of Resistant Breast Tumors.
Martin-García, Desirée; Téllez-Santana, Teresa; Redondo-Bautista, Maximino; García Aranda, Marilina (MDPI, 2023-05-23)Cancer is one of the main health problems worldwide. Only in 2020, this disease caused more than 19 million new cases and almost 10 million deaths, with breast cancer being the most diagnosed worldwide. Today, despite ... -
Cambios emocionales y alteraciones en la Inmunoglobulina A (IgA) tras el tratamiento psicológico en mujeres víctimas de violencia doméstica
Madrigal Zapata, Lucía; Cardenal, Violeta; Téllez-Santana, Teresa; Ortiz-Tallo-Alarcón, Margarita; Jimenez, Eugenio (Universidad de Murcia, 2012)El objetivo de este estudio ha sido determinar, en mujeres víctimas de maltrato, los beneficios de un tratamiento psicológico y evaluar su impacto en la salud psicológica y en el sistema inmune. Las participantes fueron ... -
Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus
Matas-Rico, Elisa; Garcia Diaz, Beatriz; Llebrez Zayas, Pedro; López-Barroso, Diana; Santín-Núñez, Luis Javier; Pedraza-Benítez, María del Carmen; Smith-Fernández, José Aníbal; Téllez-Santana, Teresa; Redondo-Bautista, Maximino; Chun, Jerold; Rodriguez-de-Fonseca, Fernando; Estivill-Torrús, Guillermo[et al.] (Elsevier, 2008)Neurogenesis persists in certain regions of the adult brain including the subgranular zone of the hippocampal dentate gyrus wherein its regulation is essential, particularly in relation to learning, stress and modulation ... -
Detection methods predict differences in biology and survival in breast cancer patients
Redondo-Bautista, Maximino; Funez, Rafael; Medina Cano, Francisco José; Rodrigo, Isabel; Acebal-Blanco, María Mercedes; Téllez-Santana, Teresa; Roldán Cardenete, María José; Hortas Nieto, María Luisa; Bellinvia, Ana; Pereda, Teresa; Domingo, Laia; Morales-Suárez-Varela, María Manuela; Sala, Maria; Rueda-Domínguez, Antonio[et al.] (BMC Springer Nature, 2012)Background: The aim of this study was to measure the biological characteristics involved in tumorigenesis and the progression of breast cancer in symptomatic and screen-detected carcinomas to identify possible difference ... -
Efecto de la inhibición de la clusterina sobre la sensibilidad a los inhibidores de proteínas quinasas en células tumorales de mama
García Aranda, Marilina (UMA Editorial, 2015)En la actualidad, el cáncer supone la segunda causa de muerte en el mundo, siendo el cáncer de mama la neoplasia maligna sólida más frecuentemente diagnosticada en las mujeres occidentales y la que presenta una mayor ... -
Factors that influence treatment delay in patients with colorectal cancer
Zarcos-Pedrinaci, Irene; Fernández López, Alberto; Téllez-Santana, Teresa; Rivas-Ruiz, Francisco; Rueda-Domínguez, Antonio; Morales-Suárez-Varela, María Manuela; Briones, Eduardo; Baré, Marisa; Escobar, Antonio; Sarasqueta, Cristina; Fernández-de Larrea-Baz, Nerea; Aguirre, Urko; Quintana, José María; Redondo-Bautista, Maximino[et al.] (IMPACT JOURNALS LLC, 2017)A prospective study was performed of patients diagnosed with colorectal cancer (CRC), distinguishing between colonic and rectal location, to determine the factors that may provoke a delay in the first treatment (DFT) ... -
Influence of depression on survival of colorectal cancer patients drawn from a large prospective cohort
Varela-Moreno, Esperanza; Rivas-Ruiz, Francisco; Padilla Ruiz, María del Carmen; Alcaide-García, Julia; Zarcos-Pedrinaci, Irene; Téllez-Santana, Teresa; Fernández-de Larrea-Baz, Nerea; Baré, Marisa; Bilbao, Amaia; Sarasqueta, Cristina; Morales-Suárez-Varela, María Manuela; Aguirre, Urko; Quintana, José María; Redondo-Bautista, Maximino[et al.] (Wiley, 2022-08-21)Objective The prevalence of depressive symptoms immediately after the diagnosis of colorectal cancer (CRC) is high and has important implications both psychologically and on the course of the disease. The aim of this ... -
Neurokinin-1 Receptor (NK-1R) Antagonists as a New Strategy to Overcome Cancer Resistance
García Aranda, Marilina; Téllez-Santana, Teresa; McKenna, Lauraine; Redondo-Bautista, Maximino (IOAP-MPDI, 2022-04-30)Nowadays, the identification of new therapeutic targets that allow for the development of treatments, which as monotherapy, or in combination with other existing treatments can contribute to improve response rates, prognosis ... -
Validation and comparison of instruments to identify frail patientes in primary care settings: Study protocol
Vergara, Itziar; Rivas-Ruiz, Francisco; Vrotsou, Kalliopi; Contreras-Fernández, Eugenio; Téllez-Santana, Teresa; Machón, Monica; Díez Ruiz, Ana Isabel; de Mesa Berenguer, Yolanda; Bueno, Andoni; et al[et al.] (BMC Springer Nature, 2016)Background: In the last few years several indices and tools, aimed at identifying frail subjects in various care settings have been developed. However, to date none of them has been incorporated into usual practice in the ...