Listar por autor "Pérez, José"
Mostrando ítems 1-10 de 10
-
A Partially Protective Vaccine for Fasciola hepatica Induced Degeneration of Adult Flukes Associated to a Severe Granulomatous Reaction in Sheep
Molina-Hernández, Verónica; Ruiz-Campillo, María Teresa; Martínez-Moreno, Francisco Javier; Buffoni, Leandro; Martinez Moreno, Álvaro; Zafra, Rafael; Bautista, María José; Escamilla-Sánchez, Alejandro
; Pérez-Caballero, Raúl; Pérez, José[et al.] (MDPI, 2021-09-30)
Fasciolosis is a parasitic disease of livestock causing important economic losses worldwide and it is also a zoonosis. Current therapy relies on the use of anthelmintic drugs, which is no longer sustainable due to the ... -
Apoptosis of peritoneal leucocytes during early stages of Fasciola hepatica infections in sheep
Escamilla-Sánchez, Alejandro; Pérez-Caballero, Raúl; Zafra, Rafael; Bautista, María José; Pacheco Luque, Isabel; Ruiz-Campillo, María Teresa; Martínez-Cruz, Setefilla; Martinez Moreno, Álvaro; Molina-Hernández, Verónica; Pérez, José[et al.] (Elsevier B.V., 2017-04)
Several immunomodulatory properties have been described in Fasciola hepatica infections. Apoptosis has been shown to be an effective mechanism to avoid the immune response in helminth infections. The aim of the present ... -
Comparative dynamics of peritoneal cell immunophenotypes in sheep during the early and late stages of the infection with Fasciola hepatica by flow cytometric analysis
Pérez-Caballero, Raúl; Martínez-Moreno, Francisco Javier; Zafra, Rafael; Molina-Hernández, Verónica; Pacheco Luque, Isabel; Ruiz-Campillo, María Teresa; Escamilla-Sánchez, Alejandro; Pérez, José; Martinez Moreno, Álvaro; Buffoni, Leandro[et al.] (Springer Nature, 2018-12)
Se cree que las poblaciones celulares peritoneales (PCP) desempeñan un papel crucial durante la respuesta inmunitaria temprana en la infección por Fasciola hepatica mientras que los juveniles recién desenquistados (NEJ) ... -
Distribution of Foxp3+ T cells in the liver and hepatic lymph nodes of goats and sheep experimentally infected with fasciola hepatica
Escamilla-Sánchez, Alejandro; Zafra, Rafael; Pérez, José; McNeilly, Tom; Pacheco Luque, Isabel; Buffoni, Leandro; Martínez-Moreno, Francisco Javier; Molina-Hernández, Verónica; Martinez Moreno, Álvaro[et al.] (Elsevier B.V., 2016-10)
Foxp3 regulatory T cells (Tregs) are now considered to play a key role in modulation of immune responses during parasitic helminth infections. Immunomodulation is a key factor in Fasciola hepatica infection; however, the ... -
Effects of topical insulin on second-intention wound healing in the red-eared slider turtle (Trachemys scripta elegans) – a controlled study
Negrini, Joao; Mozos, Elena; Escamilla-Sánchez, Alejandro; Pérez, José; Lucena, Rosario; Guerra, Rafael; Ginel, Pedro[et al.] (Springer Nature, 2017-06-06)
Compared with mammals, wound healing in reptiles is characterized by reduced wound contraction and longer healing times. The aim of this study is to describe the clinical and histopathological effects of topical insulin ... -
Fasciola hepatica Induces Eosinophil Apoptosis in the Migratory and Biliary Stages of Infection in Sheep.
Escamilla-Sánchez, Alejandro; Bautista, María José; Zafra, Rafael; Pacheco Luque, Isabel; Ruiz-Campillo, María Teresa; Martínez-Cruz, Setefilla; Méndez, Aniceto; Martinez Moreno, Álvaro; Molina-Hernández, Verónica; Pérez, José[et al.] (Elsevier, 2016-01-30)
The aim of the present work was to evaluate the number of apoptotic eosinophils in the livers of sheep experimentally infected with Fasciola hepatica during the migratory and biliary stages of infection. Four groups (n ... -
Immune signatures of pathogenesis in the peritoneal compartment during early infection of sheep with Fasciola hepatica
Ruiz-Campillo, María Teresa; Molina-Hernández, Verónica; Escamilla-Sánchez, Alejandro; Stevenson, Michael; Pérez, José; Martinez Moreno, Álvaro; Donnelly, Sheila; Dalton, John P.; Cwiklinski, Krystyna[et al.] (Springer Nature, 2017-06-05)
Immune signatures of sheep acutely-infected with Fasciola hepatica, an important pathogen of livestock and humans were analysed within the peritoneal compartment to investigate early infection. Within the peritoneum, F. ... -
Pathological, immunological and parasitological study of sheep vaccinated with the recombinant protein 14-3-3z and experimentally infected with Fasciola hepatica
Pérez-Caballero, Raúl; Siles-Lucas, Mar; González-Miguel, Javier; Martínez-Moreno, Francisco Javier; Escamilla-Sánchez, Alejandro; Pérez, José; Martinez Moreno, Álvaro; Buffoni, Leandro[et al.] (Elsevier B.V., 2018-08)
In this study, the immunogenicity and protective capacity of a new recombinant vaccine candidate, the rFh14-3-3z protein was analysed in sheep experimentally challenged with Fasciola hepatica, in terms of fluke burden, ... -
Study of peritoneal macrophage immunophenotype in sheep experimentally infected with Fasciola hepatica
Ruiz-Campillo, María Teresa; Molina-Hernández, Verónica; Pérez, José; Pacheco Luque, Isabel; Pérez-Caballero, Raúl; Escamilla-Sánchez, Alejandro; Martínez-Moreno, Francisco Javier; Martinez Moreno, Álvaro; Zafra, Rafael[et al.] (Elsevier B.V., 2018-06-15)
During Fasciola hepatica infection, the parasite has the capability to modulate the host immune response towards a non-protector Th2 type instead of Th1. This type of immune response is closely related to the alternativ ... -
Th1/Th2 balance in the liver and hepatic lymph nodes of vaccinated and unvaccinated sheep during acute stages of infection with Fasciola hepatica
Pacheco Luque, Isabel; Abril, Nieves; Morales-Prieto, Noelia; Bautista, María José; Zafra, Rafael; Escamilla-Sánchez, Alejandro; Ruiz-Campillo, María Teresa; Martinez Moreno, Álvaro; Pérez, José[et al.] (Elsevier B.V., 2017-04)
The expression of IFNγ and IL4 was quantified using q-PCR in the liver and hepatic lymph nodes (HLN) of sheep during early stages of infection with Fasciola hepatica (1, 3, 9 and 18days post-infection, dpi). A group of ...