Listar por autor "López Oliva, Elba"
Mostrando ítems 1-6 de 6
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Astroglial reactivity in response to b-amyloidosis is associated with mithocondrial pathology in the hippocampus of Alzheimer's transgenic mice
López Oliva, Elba; Trujillo-Estrada, Laura Isabel
; Sanchez Mejias, Elisabeth; Mejias-Ortega, Marina; Fernández-Valenzuela, Juan José; Gomez-Arboledas, Angela; Dávila-Cansino, José Carlos; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia[et al.] (2023-04)
Aims: Alzheimer’s diseaase (A)D is associated with early energy hypometabolism, synaptic and mitochondrial dysfunction, oxidative stress, inflammation, abnormal proteostasis and progressive neurodegeneration. During the ... -
Co-cultures between neurons and astrocytes to address Alzheimer´s disease pathology.
Cáceres Palomo, Laura; García-León, Juan Antonio; Trujillo-Estrada, Laura Isabel; López Oliva, Elba; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia[et al.] (2023)
Background: Alzheimer's disease (AD) is characterized by presenting a complex pathology, not fully resolved yet. This fact, together with the lack of reliable models, has impeded the development of effective therapies. ... -
Comparing astroglial reactivity in two transgenic mouse models of tauopathy
Fernández-Valenzuela, Juan José; Sanchez Varo, Raquel; López Oliva, Elba; Romero Molina, Carmen; Mejias Ortega, Marina; Sánchez-Mejías, Elisabet; Vizuete, María Luisa; Dávila-Cansino, José Carlos; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia[et al.] (2021-11-03)
Astrocytes are becoming crucial players in the pathology of neurodegenerative disorders, such as Alzheimer’s disease (AD). Astrocyte responses have been mainly analyzed in the context of amyloid-beta (Abeta) pathology, ... -
Glia and neurons from human iPSCs to address the pathology of Alzheimer´s disease
García-León, Juan Antonio; Cáceres Palomo, Laura; Trujillo Estrada, Laura; López Oliva, Elba; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia[et al.] (2023)
Alzheimer's disease (AD) is characterized by presenting a complex pathology, not fully resolved yet. This fact, together with the lack of reliable models, has impeded the development of effective therapies. Recently, ... -
Human pluripotent stem cell-derived astrocytes from alzheimer´s disease patients for disease modeling
Cáceres Palomo, Laura; López Oliva, Elba; Dávila-Cansino, José Carlos; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia; García-León, Juan Antonio[et al.] (2022)
Aims: The lack of reliable models of Alzheimer´s disease (AD) has impeded the development of effective therapies. Glial cells have a key role in AD pathology, but this cannot be properly modeled using available animal ... -
Tau pathology and astroglial reactivity: a comparative study of two mouse models of tauopathy
Fernández-Valenzuela, Juan José; López Oliva, Elba; Sánchez-Varo, Raquel María; Sánchez-Mejías, Elisabet; Romero, Carmen; Mejias-Ortega, Marina; Vizuete, María Luisa; Dávila-Cansino, José Carlos; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia[et al.] (2022)
Objectives: Astrocytes are becoming crucial players in the context of neurodegenerative proteinopathies, such as Alzheimer’s disease (AD). Astroglial response has been mainly analyzed in amyloidogenic scenarios, but less ...