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Anxiety associated with palatable food withdrawal is reversed by the selective FAAH inhibitor PF-3845: A regional analysis of the contribution of endocannabinoid signaling machinery
De Ceglia, Marialuisa; Micioni Di Bonaventura, Maria Vittoria; Romano, Adele; Friuli, Marzia; Micioni Di Bonaventura, Emanuela; Gavito, Ana L.; Botticelli, Luca; Gaetani, Silvana; Rodriguez-de-Fonseca, Fernando; Cifani, Carlo[et al.] (Wiley, 2023)Objective: Consumption of energy-dense palatable "comfort" food can alleviate stress and negative emotions, while abrupt withdrawal from a palatable diet can worsen these symptoms, causing difficulties with adherence to ... -
Dietary administration of D-chiro-inositol attenuates sex-specific metabolic imbalances in the 5xFAD mouse model of Alzheimer’s disease
López-Gambero, Antonio J.; Pacheco-Sánchez, Beatriz; Rosell-del-Valle, Cristina; Medina-Vera, Dina; Navarro, Juan Antonio; Fernández-Arjona, María del Mar; De Ceglia, Marialuisa; Sanjuán-Solís, Jesús Carlos; Simon, Vincent; Cota, Daniela; Rivera, Patricia; Rodriguez-de-Fonseca, Fernando; Suárez, Juan[et al.] (Elsevier, 2022-06)
Increasing evidence shows that hypothalamic dysfunction, insulin resistance, and weight loss precede and progress along with the cognitive decline in sporadic Alzheimer’s Disease (AD) with sex differences. This study aimed ... -
Endocrine and Metabolic impact of oral ingestion of a carob-pod derived natural syrup containing D-Pinitol: potential use as a novel sweetener in diabetes
Navarro, Juan Antonio; Decara, Juan; Dina, Medina; Tovar, Ruben; López-Gambero, Antonio J.; Pavón, Francisco Javier; Serrano, Antonia; De Ceglia, Marialuisa; Sanjuan, Carlos; Rodriguez-de-Fonseca, Fernando; Baixeras-Llano, Elena[et al.] (EMBO, 2022)
The use of added sugars or non-nutritive sweeteners in processed foods and soft drinks are being blamed for multiple complications associated with obesity and diabetes. High fructose content contributes to obesity and liver ...