Listar por autor "Lara, Estrella"
Mostrando ítems 1-5 de 5
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Fingolimod phosphate protection against mitochondrial damage in neuronal cells
Martin-Montañez, Elisa
; Álvarez-Gil, Antonio; Valverde, Nadia; Lara, Estrella; de Luque, Vanesa; Boraldi, Federica; Urbano, María; García-Fernández, Maria Inmaculada; Pavia-Molina, Jose[et al.] (Elsevier, 2019-04-17)
Background: Major role of oxidative stress in the pathogenesis of neurodegenerative diseases have been suggested, being mitochondria one of the main sources of ROS. Aim: In the present work, we have studied the antioxidant ... -
Insulin-like growth factor II neuroprotective effects against mitochondrial-oxidative and neuronal damage induced by CORT and MPP+ in dopaminergic neurons
Claros-Gil, Silvia; Cabrera, Pablo; Valverde, Nadia; Romero Zerbo, Silvana Yanina; Lara, Estrella; López-González, Manuel Víctor; Shumilov, Kirill; Rivera-Ramirez, Alicia; Pavia-Molina, Jose; Martin-Montañez, Elisa; García-Fernández, Maria Inmaculada[et al.] (2022-07-12)
Aims: Parkinson’s disease (PD) affects 1–3% of the population aged over 65. Stress seems to contribute to PD neuropathology, probably by dysregulation of the hypothalamic–pituitary–adrenal axis. Key factors are oxidative ... -
Neuroprotective effects of insulin-like growth factor II in a mouse model of Parkinson's disease
Ladrón de Guevara-Miranda, David; Martin-Montañez, Elisa; Valverde, Nadia; Lara, Estrella; Romero Zerbo, Silvana Yanina; Millon-Peñuela, Carmelo; Boraldi, Federica; Ávila-Gámiz, Fabiola; Pérez-Cano, Ana María; Garrido-Gil, Pablo; Labandeira-García, José Luis; Santin-Nuñez, Luis Javier; Pavia-Molina, Jose; García-Fernández, Maria Inmaculada[et al.] (2022-07-20)
Progressive degeneration of the nigrostriatal dopaminergic pathway is a core, currently irreversible pathological hallmark of Parkinson’s disease (PD) that leads to a variety of motor and non-motor symptoms. Here, we aimed ... -
Papel del receptor S1P sobre el estrés oxidativo mitocondrial en cultivo neuronal
Valverde, Nadia; Lara, Estrella; Álvarez-Gil, Antonio; de Luque, Vanesa; Boraldi, Federica; Pavia-Molina, Jose; Fernández, Oscar; Martin-Montañez, Elisa; García-Fernández, Maria Inmaculada[et al.] (2019-06-25)
Introducción: Fingolimod, fármaco inmunomodulador, presenta propiedades neuroprotectoras que podrían promover la recuperación de la función cognitiva en enfermedades neurodegenerativas. El estrés oxidativo parece tener un ... -
Role of Insulin-Growth Factor II on mitochondrial recovery in a cellular model of Parkinson's Disease
Valverde, Nadia; Romero Zerbo, Silvana Yanina; Lara, Estrella; Claros-Gil, Silvia; Pavia-Molina, Jose; Martin-Montañez, Elisa; García-Fernández, Maria Inmaculada[et al.] (Journal of Physiology and Biochemistry, 2022-09)
Insulin-growth factor II (IGF-II) has shown antioxidant and neuroprotective effects in some neurodegenerative disorders. ROS causes damage to cellular macromolecules affecting several cellular processes and resulting in ...