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Listar por autor "Ribelles, Nuria"
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A Carboxylesterase 2 Gene Polymorphism as Predictor of Capecitabine on Response and Time to Progression
Ribelles, Nuria; López-Siles, J; Sánchez-Muñoz, Alfonso; Sánchez, E; González, E; Sánchez, MJ; Carabantes, F; Sánchez- Rovira, P; Márquez, A; Dueñas, R; Sevilla, I; Alba-Conejo, Emilio[et al.] (Bentham Science Publishers Ltd, 2008)Capecitabine is a drug that requires the consecutive action of three enzymes: carboxylesterase 2 (CES 2), cytidine deaminase (CDD), and thymidine phosphorylase (TP) for transformation into 5-fluorouracil (5FU). The ... -
A randomized phase II trial of platinum salts in basal-like breast cancer patients in the neoadjuvant setting. Results from the GEICAM/2006-03, multicenter study
Alba-Conejo, Emilio; Chacón, J. L.; Lluc, A.; Antón, A.; Estévez, L.; Cirauqui, B.; Carrasco, E.; Calvo, L.; Seguí, M.A.; Ribelles, Nuria; Álvarez, R.; Sánchez-Muñoz, Alfonso; Sánchez, R.; Lopez Garcia-Asenjo, J.A.; Rodriguez-Martin, C.; Escudero, M.J.; Albanell, J.[et al.] (Springer, 2012-10)Abstract Chemotherapy remains as the only systemic treatment option available for basal-like breast cancer (BC) patients. Preclinical models and several phase II studies suggested that platinum salts are active drugs in ... -
Clinical text classification in Cancer Real-World Data in Spanish
Moreno-Barea, Francisco J.; Mesa, Héctor; Ribelles, Nuria; Alba-Conejo, Emilio; Jerez-Aragonés, José Manuel (2023-06-29)Healthcare systems currently store a large amount of clinical data, mostly unstructured textual information, such as electronic health records (EHRs). Manually extracting valuable information from these documents is costly ... -
Design and implementation of a standard care programme of therapeutic exercise and education for breast cancer survivors
Roldán-Jiménez, Cristina; Pajares, Bella; Ruiz-Medina, Sofía; Trinidad-Fernández, Manuel; González-Sánchez, Manuel; Ribelles, Nuria; García-Almeida, José Manuel; Ríos-López, María José[et al.] (SPRINGER, 2021-08-31)Background Breast cancer survivors (BCS) face several symptoms and are at higher risk of weight gain following diagnosis. Current literature shows that both exercise and diet play a key role in recovery of BCS. However, ... -
Detection of tumor morphology mentions in clinical reports in Spanish using transformers
López-García, Guillermo; Jerez-Aragonés, José Manuel; Ribelles, Nuria; Alba-Conejo, Emilio; Veredas-Navarro, Francisco Javier (Springer, 2021)The aim of this study is to systematically examine the performance of transformer-based models for the detection of tumor morphology mentions in clinical documents in Spanish. For this purpose, we analyzed 3 transformer ... -
Efecto de la quimioterapia neoadyuvante en la variación de receptores hormonales, Her2 y Ki67 en pacientes con cáncer de mama
Álvarez-Pérez, Martina; Lavado-Fernández, Ana Isabel; Pérez-Villa, Lidia; Lozano, María José; Jiménez-Rodríguez, Begoña; De Luque, Vanesa; Jiménez-Vista, Álvaro; Ventura, Carmen; Jiménez-Fernández, Ana; Rodrigo-Fernández, Isabel; Ramírez-Tortosa, César; Ribelles, Nuria; Alba-Conejo, Emilio; Vicioso-Recio, Luis Prudencio[et al.] (2016-03-02)Introducción:Existe controversia respecto al impacto de la quimioterapia en la expresión de marcadores inmunohistoquímicos del cáncer de mama, ya que pueden existir cambios en los marcadores tumorales entre las biopsias ... -
Estudio de factores anatomopatológicos predictivos de respuesta patológica a quimioterapia neoadyuvante y su valor pronóstico en el cáncer de mama
Lavado Fernández, Ana Isabel (UMA Editorial, 2017-07-09)La quimioterapia neoadyuvante (QTN) se utiliza cada vez más para conseguir una reducción tumoral que permita una cirugía conservadora y, mediante el grado de respuesta patológica tumoral, poder determinar el pronóstico de ... -
Estudio de factores predictivos de respuesta patológica a quimioterapia neoadyuvante en el cáncer de mama receptores hormonales positivos HER2 negativo
Lavado-Fernández, Ana Isabel; Álvarez-Pérez, Martina; Prieto Cuadra, Juan Daniel; Jiménez-Rodríguez, Begoña; Lozano, María José; De Luque, Vanesa; Jiménez-Vista, Álvaro; Ventura, Carmen; Jiménez-Fernández, Ana; Rodrigo, Isabel; Ramírez, César; Cano, Tatiana; González-Zafra, Virginia; Pérez-Villa, Lidia; Gallego-Domínguez, Elena María; Ortega-Jiménez, María Victoria; Arranz-Salas, Isabel María; Ribelles, Nuria; Alba-Conejo, Emilio; Vicioso-Recio, Luis Prudencio[et al.] (2015-07-02)La quimioterapia neoadyuvante (QTN) se utiliza cada vez más para conseguir una reducción tumoral que permita una cirugía conservadora y, mediante el grado de respuesta patológica tumoral, determinar el pronóstico de las ... -
Explainable clinical coding with in-domain adapted transformers
López-García, Guillermo; Jerez-Aragonés, José Manuel; Ribelles, Nuria; Alba-Conejo, Emilio; Veredas-Navarro, Francisco Javier (Elsevier, 2023)Background and Objective: Automatic clinical coding is a crucial task in the process of extracting relevant in-formation from unstructured medical documents contained in Electronic Health Records (EHR). However, most of ... -
Lack of evidence for KRAS oncogenic mutations in triple-negative breast cancer.
Sánchez-Muñoz, Alfonso; Gallego-Domínguez, Elena María; De Luque, Vanesa; Pérez-Rivas, Luis G.; Vicioso-Recio, Luis Prudencio; Ribelles, Nuria; Lozano-Castro, José; Alba-Conejo, Emilio[et al.] (Springer Nature, 2010-04-13)Background: Mutational analysis of the KRAS gene has recently been established as a complementary in vitro diagnostic tool for the identification of patients with colorectal cancer who will not benefit from anti-epidermal ... -
Named Entity Recognition for De-identifying Real-World Health Records in Spanish.
López-García, Guillermo; Moreno-Barea, Francisco J.; Mesa, Héctor; Jerez-Aragonés, José Manuel; Ribelles, Nuria; Alba-Conejo, Emilio; Veredas-Navarro, Francisco Javier[et al.] (Springer Nature, 2023)A growing and renewed interest has emerged in Electronic Health Records (EHRs) as a source of information for decision-making in clinical practice. In this context, the automatic de-identification of EHRs constitutes an ... -
Serum protein levels following surgery in breast cancer patients: A protein microarray approach
Pérez-Rivas, Luis G.; Jerez, J.M.; Fernández-De Sousa, C.E.; De Luque, Vanesa; Quero, C.; Pajares, B.; Franco, L.; Sánchez-Muñoz, Alfonso; Ribelles, Nuria; Alba-Conejo, Emilio[et al.] (Spandidos Publications, 2012-07)Surgery is the primary treatment for non-metastatic breast cancer. However, the risk of early recurrence remains after surgical removal of the primary tumor. Recurrence is suggested to result from hidden micrometastatic ... -
Validation of the upper limb functional index on breast cancer survivor
Martín-Martín, Jaime; Pajares-Hachero, Bella I.; Alba-Conejo, Emilio; Ribelles, Nuria; Cuesta-Vargas, Antonio; Roldán-Jiménez, Cristina[et al.] (MDPI, 2023-03-12)Breast cancer survivors (BCS) may face functional alterations after surgical intervention. Upper Limb Disorders (ULDs) are highly prevalent even years after a diagnosis. Clinicians may assess the upper limbs after breast ...