Listar por autor "Navarro, Juan Antonio"

Mostrando ítems 1-3 de 3

d-Pinitol promotes tau dephosphorylation through a cyclin-dependent kinase 5 regulation mechanism: A new potential approach for tauopathies?

Medina-Vera, Dina; Navarro, Juan Antonio; Rivera, Patricia (WILEY, 2022-06-27)

Background and Purpose Recent evidence links brain insulin resistance with neurodegenerative diseases, where hyperphosphorylated tau protein contributes to neuronal cell death. In the present study, we aimed to evaluate ...
Dietary administration of D-chiro-inositol attenuates sex-specific metabolic imbalances in the 5xFAD mouse model of Alzheimer’s disease

López-Gambero, Antonio J.; Pacheco-Sánchez, Beatriz; Rosell-Valle, Cristina; Medina-Vera, Dina; Navarro, Juan Antonio; [et al.] (Elsevier, 2022-06)

Increasing evidence shows that hypothalamic dysfunction, insulin resistance, and weight loss precede and progress along with the cognitive decline in sporadic Alzheimer’s Disease (AD) with sex differences. This study aimed ...
Endocrine and Metabolic impact of oral ingestion of a carob-pod derived natural syrup containing D-Pinitol: potential use as a novel sweetener in diabetes

Navarro, Juan Antonio; Decara, Juan; Dina, Medina; Tovar, Ruben; López-Gambero, Antonio; [et al.] (EMBO, 2022)

The use of added sugars or non-nutritive sweeteners in processed foods and soft drinks are being blamed for multiple complications associated with obesity and diabetes. High fructose content contributes to obesity and liver ...