Listar por autor "Cifuentes-Rueda, Manuel"
Mostrando ítems 1-13 de 13
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A model of neuroinflammation and demyelination by intracerebroventricular injection of microbial neuraminidase
Fernández-Llebrez, Pedro
; Granados-Durán, Pablo; Gómez-Roldán, María del Carmen; Cifuentes-Rueda, Manuel; Pérez-Martín, Margarita; Mateos-Grondona, Jesús; Rodriguez-de-Fonseca, Fernando; López-Ávalos, María Dolores[et al.] (2014-07-14)
Neuraminidase from Clostridium perfringens, which cleaves terminal sialic acid from carbohydrate chains, was injected in the lateral ventricle of rats. It diffused in the ipsilateral ventricle, the third ventricle, and ... -
A synthetic collagen-binding arg-gly-asp (rgd) biomimetic peptide enhances bone cell differentiation
Visser, Rick; Arrabal-Garcia, Pilar Maria; Santos-Ruiz, Leonor; Fernández-Barranco, Raúl; Cifuentes-Rueda, Manuel; Becerra-Ratia, Jose[et al.] (2013-11-27)
RGD (arginine-glycine-aspartic acid) peptides have shown some promising abilities to promote the attachment of cells to biomaterials and to direct their differentiation. However, anchoring these peptides to the biomaterial’s ... -
Bone marrow mesenchymal stem cells, collagen scaffold and BMP-2 for rat spinal fusio
Arrabal-Garcia, Pilar Maria; Visser, Rick; Cifuentes-Rueda, Manuel; Becerra-Ratia, Jose; Jiménez-Enjuto, E. (2013-11-08)
The use of autograft for posterolateral spinal fusion, continue being considered the gold standard for the treatment of spine pathologies. However, due to complications such as donor site morbidity, increased operating ... -
Bone marrow-derived mesenchymal stem cells characterization and transplantation in an animal model of congenital hydrocephalus
García-Bonilla, María; Cifuentes-Rueda, Manuel; Ho-Plagaro, Ailec; Santos-Ruiz, Leonor; Shumilov, Kirill; Pérez-Fígares, José Manuel; Jimenez-Lara, Antonio Jesus[et al.] (2015-10-08)
Congenital hydrocephalus is a disorder presenting a degeneration of the periventricular cerebral parenchyma and the white matter, which causes significant mortality and life-long neurological complications. There are ... -
Characterization and administration of bone marrow-derived mesenchymal stem cells in an animal model of congenital hydrocephalus
García-Bonilla, María; Cifuentes-Rueda, Manuel; Ho-Plagaro, Ailec; Shumilov, Kirill; Santos-Ruiz, Leonor; Pérez-Fígares, José Manuel; Jimenez-Lara, Antonio Jesus[et al.] (2015-07-08)
Bone marrow-derived mesenchymal stem cells (BM-MSC) are considered as a potential therapeutic tool in neurodegenerative diseases, due to their ability to migrate to degenerated tissues and the production of growth factors. ... -
Effect of bone marrow-derived mesenchymal stem cells on congenital hydrocephalus in the hyh mouse
García-Bonilla, María; Shumilov, Kirill; Vitorica, Javier; García-Martín, María Luisa; Muñoz, Carmen; Jimenez, Sebastian; Navarro, Victoria; García-Cuervo, Luisa; Cifuentes-Rueda, Manuel; Claros-Gil, Silvia; Andrades-Gomez, Jose Antonio; Guitérrez, Antonia; Paez-Gonzalez, Patricia; Jimenez-Lara, Antonio Jesus[et al.] (2017-06-28)
Background Bone marrow-derived mesenchymal stem cells (BM-MSC) are considered as a potential therapeutic tool for neurodegenerative diseases due to their ability for migrating into damaged tissue. Additionally, these cells ... -
IGF-I stimulates cell proliferation in a specific area of the hypothalamic wall
Pérez-Martín, Margarita; Cifuentes-Rueda, Manuel; Mateos-Grondona, Jesús; López-Ávalos, María Dolores; Fernández-Llebrez, Pedro (2015-09-15)
Neurogenesis in the adult rat hippocampal subgranular zone and the subventricular zone of the lateral ventricles has been well documented. Increasing evidence suggests that neurogenesis also occurs in the adult hypothalamus. ... -
LPA1 receptor and chronic stress: Effects on behaviour and the genes involved in the hippocampal excitatory/inhibitory balance.
Moreno-Fernández, R.; Rosell-del-Valle, Cristina; Bacq, Alexandre; Zanoletti, Olivia; Cifuentes-Rueda, Manuel; Pérez-Martín, Margarita; Gavito, A.L.; García-Fernández, Maria Inmaculada; Estivill-Torrús, Guillermo; Rodriguez-de-Fonseca, Fernando; Santin-Nuñez, Luis Javier; Sandi, Carmen; Pedraza-Benítez, Maria del Carmen[et al.] (Neuropharmacology, 2020-03-01)
The LPA1 receptor, one of the six characterized G protein-coupled receptors (LPA1-6) through which lysophosphatidic acid acts, is likely involved in promoting normal emotional behaviours. Current data suggest that the ... -
Social avoidance and altered stress axis in a mouse model of anxious depression
Nieto-Quero, Andrea; Gómez-Salas, Francisco Javier; Moreno-Fernández, Román; Rosell-del-Valle, Cristina; Pérez-Martín, Margarita; Cifuentes-Rueda, Manuel; García-Fernández, Maria Inmaculada; Chun, Jerold; Estivill-Torrús, Guillermo; Rodriguez-de-Fonseca, Fernando; Santin-Nuñez, Luis Javier; Pedraza-Benítez, Maria del Carmen[et al.] (2018-07-17)
Prevalence of stress-related disorders, such as depression, is raising in modern societies. Indeed, current neurobiological research aims to elucidate the link between deregulation of the hypothalamic-pituitary-adrenal ... -
Stress, depression and the hippocampus: modulatory effects of continuous LPA treatment
Moreno-Fernández, Román; Bacq, Alexandre; Rosell-del-Valle, Cristina; Zanoletti, Olivia; Cifuentes-Rueda, Manuel; Pérez-Martín, Margarita; García-Fernández, Maria Inmaculada; Estivill-Torrús, Guillermo; Rodriguez-de-Fonseca, Fernando; Santin-Nuñez, Luis Javier; Sandi, Carmen; Pedraza-Benítez, Maria del Carmen[et al.] (2019-06-25)
The LPA1, one of the six characterized G protein-coupled receptors (LPA1–6) through which lysophosphatidic acid acts may be involved in promoting normal emotional behaviors. Evidence also imply a role for the LPA1 receptor ... -
The effect of combining bone morphogenetic proteins -2 and -6 on osteoblastic differentiation and bone
Rico-Llanos, Gustavo Adolfo; Bodnárová, Kristina; Arrabal-Garcia, Pilar Maria; Cifuentes-Rueda, Manuel; Becerra-Ratia, Jose (2015-07-21)
Bone morphogenetic proteins-2 and -7 (BMP-2 and -7) are the only two members of the BMP subfamily approved to date to be used in combination with collagen type I in orthopedic surgery, although other BMPs have proven to ... -
The ependymal detach due to neuraminidase provokes hydrocephalus
Fernández-Arjona, María del Mar; Granados-Durán, Pablo; Gómez-Roldán, María del Carmen; López-Ávalos, María Dolores; Mateos-Grondona, Jesús; Cifuentes-Rueda, Manuel; Pérez-Martín, Margarita; Fernández-Llebrez, Pedro[et al.] (2015-05-27)
Background: In many cases there seems to exist a tight relationship between the integrity of the ependymal barrier and the onset of hydrocephalus (see 1). We wanted to investigate this by means of a repetitive model that ... -
Vitamin C Deficiency Reduces Neurogenesis and Proliferation in the SVZ and Lateral Ventricle Extensions of the Young Guinea Pig Brain
Jara, Nery; Cifuentes-Rueda, Manuel; Martínez, Fernando; Gonzalez-Chavarria, Ivan; Salazar, Katterine; Ferrada, Lucas; Nualart, Francisco[et al.] (IOAP-MPDI, 2022-10-14)
Although scurvy, the severe form of vitamin C deficiency, has been almost eradicated, the prevalence of subclinical vitamin C deficiency is much higher than previously estimated and its impact on human health might not be ...