Listar por autor "Khan, Zafar U."
Mostrando ítems 1-4 de 4
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A correlation of haloperidol-induced cognitive deficit with dysfunctional dopamine receptor activity in nonhuman primate.
(Dovepress, 2010-05-04)Haloperidol is an antipsychotic drug that acts through blockage of dopamine D2 receptors. Chronic administration of this antipsychotic drug in nonhuman primates induces a pronounced cognitive deficit. However, receptor ... -
AMPA receptors in synaptic plasticity, memory function, and brain diseases
(Springer Nature, 2025-01-22)Tetrameric AMPA-type ionotropic glutamate receptors are primary transducers of fast excitatory synaptic transmission in the central nervous system, and their properties and abundance at the synaptic surface are crucial ... -
Early neuropathology of somatostatin/NPY GABAergic cells in the hippocampus of a PS1xAPP transgenic model of Alzheimer's disease.
Ramos, Blanca; Baglietto-Vargas, David; del Rio, Juan Carlos; Moreno-González, Inés; Santa-Maria, Consuelo; Jiménez, Sebastián; Caballero, Cristina; López-Téllez, Juan Félix; Khan, Zafar U.; Ruano, Diego; Gutiérrez-Pérez, Antonia
; Vitorica Ferrández, Javier[et al.] (Elsevier, 2006-11)
At advanced stages, Alzheimer's disease (AD) is characterized by an extensive neuronal loss. However, the early neurodegenerative deficiencies have not been yet identified. Here we report an extensive, selective and early ... -
Prefrontal Inositol Triphosphate Is Molecular Correlate of Working Memory in Nonhuman Primates.
López-Téllez, Juan Félix; López-Aranda, Manuel Francisco; Navarro-Lobato, Irene; Masmudi-Martín, Mariam; Martín-Montañez, Elisa; Blanco-Calvo, Eduardo; Khan, Zafar U.[et al.] (Society for Neuroscience, 2010-02-24)
Working memory (WM) is a process of actively maintaining information in the mind for a relatively short period of time, and prefrontal cortex (PFC) has been thought to play a central role in its function. However, our ...