Listar por autor "Morris, Andrew"

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Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells

Matas-Rico, Elisa; Frijlink, Elselien; Morris, Andrew; Moolenaar, Wouter H; Koster, Jan; van der Haar, Irene; Menegakis, Apostolos; van Zon, Maaike; Salgado-Polo, Fernando; De Kivit, Sander; Johnson, Zoe; Haanen, John; Schumacher, Ton; Borst, Jannie; Verbrugge, Inge; van den Berg, Joost; Perrakis, Anastassis[et al.] (2022)

To improve the efficacy of immunotherapy, it is essential to better understand how cytotoxic CD8+ T cells infiltrate into tumors. Here, we examine a role for autotaxin (ATX) in this process. ATX (encoded by ENPP2) is a ...