Listar por autor "Zambrana-Infantes, Emma"
Mostrando ítems 1-13 de 13
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Acute psychological stress: effects on hippocampal neurogenesis and the role of microglia
Nieto-Quero, Andrea; Chaves-Peña, Patricia; Infantes-López, M. Inmaculada; Zambrana-Infantes, Emma; Tabbai, Sara; Muñoz-Martin, José; Pérez-Martín, Margarita
; Pedraza-Benítez, Maria del Carmen[et al.] (2022)
Among all the factors that can contribute to the onset of psychopathological disorders, stress is the main environmental factor. The hippocampus is one of the most sensitive regions to the harmful effects of stress, in ... -
Chronic central modulation of LPA/LPA receptors-signaling pathway in the mouse brain regulates cognition, emotion, and hippocampal neurogenesis.
Rosell-del-Valle, Cristina; Pedraza-Benítez, Maria del Carmen; Manuel, Iván; Moreno-Rodríguez, Marta; Rodríguez-Puertas, Rafael; Castilla-Ortega, María Estela; Carames-Tejedor, Jose Maria; Gómez-Conde, Ana Isabel; Zambrana-Infantes, Emma; Ortega-Pinazo, Jesús; Serrano-Castro, Pedro Jesus; Chun, Jerold; Rodriguez-de-Fonseca, Fernando; Santin-Nuñez, Luis Javier; Estivill-Torrús, Guillermo[et al.] (Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2021-06-06)
Several studies have demonstrated that lysophosphatidic acid (LPA) acts through its LPA receptors in multiple biological and behavioral processes, including adult hippocampal neurogenesis, hippocampal-dependent memory, and ... -
Efectos de la Palmitoiletanolamida en la adicción a cocaína: influencia en la sensibilización conductual y en el condicionamiento preferencial de lugar.
(UMA Editorial, 2016)La adicción a cocaína supone un problema, tanto a nivel individual como social, puesto que conlleva numerosas complicaciones sanitarias para los consumidores e importantes costes económicos para el sistema de salud. La ... -
Effects of chronic stress on hippocampal microglia and neurogenesis of mice under social defeat stress.
Muñoz-Martín, José; Infantes-López, M. Inmaculada; Chaves-Peña, Patricia; Nieto-Quero, Andrea; Zambrana-Infantes, Emma; Pedraza-Benítez, Maria del Carmen; Pérez-Martín, Margarita[et al.] (2022-07)
Introduction: Chronic stress is the main environmental factor in the aetiology of depression and it is known that this type of stress may cause alterations in brain regions such as the hippocampus. Nevertheless, changes ... -
Effects of palmitoylethanolamide in cocaine-induced behaviours
Santin-Nuñez, Luis Javier; Zambrana-Infantes, Emma; Galeano, Pablo; Rosell-del-Valle, Cristina; Ladrón de Guevara-Miranda, David; Castilla-Ortega, María Estela; Rodriguez-de-Fonseca, Fernando; Blanco-Calvo, Eduardo[et al.] (2016-07-13)
Aims. Cocaine addiction is a chronically relapsing disorder characterized by the compulsion to seek and take the drug. Previous investigations have demonstrated that several drugs of abuse, as cocaine, can alter the levels ... -
Effects of sequential exposure to physical exercise and cognitive training on hippocampal neurogenesis in mice
Ávila-Gámiz, Fabiola; Pérez-Cano, Ana María; Mullor-Vigo, Rosa; Perez-Berlanga, José Manuel; Zambrana-Infantes, Emma; Santin-Nuñez, Luis Javier; Ladrón de Guevara-Miranda, David[et al.] (2022-07-13)
AIMS: Physical exercise and cognitive training hippocampal dependent tasks are known to enhance adult hippocampal neurogenesis (AHN). Here we aimed to evaluate the effect of either a moderate-intensity exercise protocol, ... -
Effects on the hippocampal microglia after acute treatment of a psychological stressor associated with depressive-like behaviours
Nieto-Quero, Andrea; Infantes-López, M. Inmaculada; Zambrana-Infantes, Emma; Chaves-Peña, Patricia; Tabbai-Amal, Sara; Pérez-Martín, Margarita; Pedraza-Benítez, Maria del Carmen[et al.] (2021-07)
Stressful life events may have a negative impact on mental health compromising people's well-being, so knowing the neurobiological changes that occur after psychosocial stressors can have an impact on overall health. ... -
Influence of neurogenic improvement strategies on extinction and reinstatement of cocaine-induced conditioned place preference
Mullor-Vigo, Rosa; Ávila-Gámiz, Fabiola; Zambrana-Infantes, Emma; Mañas Padilla, María del Carmen; Gil Rodríguez, Sara; Santin-Nuñez, Luis Javier; Ladrón de Guevara-Miranda, David; Santin-Nuñez, Luis Javier[et al.] (2022)
AIMS: Modulation of adult hippocampal neurogenesis (AHN) has been shown to influence the maintenance of drug-context associations. We aimed to study whether the enhancement of AHN by using a water maze spatial learning ... -
Microglial and neurogenic alterations in hypothalamus due to acute stress
Infantes-López, M. Inmaculada; Nieto-Quero, Andrea; Zambrana-Infantes, Emma; Chaves-Peña, Patricia; Tabbai-Amal, Sara; Pedraza-Benítez, Maria del Carmen; Pérez-Martín, Margarita[et al.] (2021-07)
Microglial cells are an important glial population known to be involved in several biological processes such as stress response. These cells engage an activated state following a stress insult that may lead to nervous ... -
Sequential treadmill exercise and cognitive training synergistically increase adult hippocampal neurogenesis in mice
Ávila-Gámiz, Fabiola; Pérez-Cano, Ana María; Perez-Berlanga, José Manuel; Mullor-Vigo, Rosa; Zambrana-Infantes, Emma; Santin-Nuñez, Luis Javier; Ladrón de Guevara-Miranda, David[et al.] (Elsevier, 2023)
Combining physical and cognitive training has been suggested to promote further benefits on brain and cognition, which could include synergistic improvement of hippocampal neuroplasticity. In this paper, we investigated ... -
Social defeat stress induces microglial alterations and impaired cell survival in the hypothalamus according to behavioral phenotype
Infantes-López, M. Inmaculada; Zambrana-Infantes, Emma; Chaves-Peña, Patricia; Nieto-Quero, Andrea; Muñoz-Martín, José; Pedraza-Benítez, Maria del Carmen; Pérez-Martín, Margarita[et al.] (2022-07)
Stress is the main environmental cause for depression, known to cause brain immune alterations. As major brain immune cells, microglia undergo transcriptional and, consequently, morphological changes that result in ... -
Spatial training in the Water Maze facilitates extinction and prevents reinstatement of cocaine-induced Conditioned Place Preference
Ávila-Gámiz, Fabiola; Mañas Padilla, María del Carmen; Gil Rodríguez, Sara; Zambrana-Infantes, Emma; Santin-Nuñez, Luis Javier; Ladrón de Guevara-Miranda, David[et al.] (2021)
Manipulation of adult hippocampal neurogenesis has been shown to affect the establishment of cocaine-context associations as well as extinction learning and reinstatement of these maladaptive memories. In this work, we ... -
What role does the LPA1 receptor play in regulating emotional-like behaviours?
Pedraza-Sánchez-López, J.; Castilla-Ortega, María Estela; Rosell-del-Valle, Cristina; Moreno-Fernández, Román D.; Zambrana-Infantes, Emma; García-Fernández, Maria Inmaculada; Rodriguez-de-Fonseca, Fernando; Chun, Jerold; Estivill-Torrús, Guillermo; Santin-Nuñez, Luis Javier[et al.] (2015-07-24)
The LPA1 receptor is one of the six characterized G protein-coupled receptors (LPA1–6) through which lysophosphatidic acid acts as an intercellular signalling molecule. It has been proposed that this receptor has a role ...