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Listar por autor "Cueto-Sánchez, Alejandro"
Mostrando ítems 1-5 de 5
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Differential iNKT and T cells activation in non-alcoholic fatty liver disease and drug-induced liver injury.
Caballano-Infantes, Estefanía; García-García, Alberto; Lopez-Gomez, Carlos; Cueto-Sánchez, Alejandro; Robles-Díaz, María Mercedes; Ortega-Alonso, Aida; Martín-Reyes, Flores; Alvarez-Alvarez, Ismael; Arranz-Salas, Isabel María
; Ruiz-Cabello, Francisco; Lucena-González, María Isabel
; García-Fuentes, Eduardo; Andrade-Bellido, Raúl Jesús
; García-Cortés, Miren
[et al.] (MDPI, 2021-01-28)
Background: Non-alcoholic fatty liver disease (NAFLD) and idiosyncratic drug-induced liver injury (DILI) could share molecular mechanisms involving the immune system. We aimed to identify activation immunological biomarkers ... -
Evaluation of diagnostic and prognostic candidate biomarkers in drug-induced liver injury vs. other forms of acute liver damage
Cueto-Sánchez, Alejandro; Niu, Hao; Alvarez-Alvarez, Ismael; López-Longarela, Bárbara; Del Campo-Herrera, Enrique; Ortega-Alonso, Aida; García-Cortés, Miren; Pinazo-Bandera, José M.; Sanabria-Cabrera, Judith Adriana
; Díaz-Monchón, Juan José; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
; Stephens, Camilla; Robles-Díaz, María Mercedes
[et al.] (Wiley, 2023)
Aims Detection and characterization of idiosyncratic drug-induced liver injury (DILI) currently rely on standard liver tests, which are suboptimal in terms of specificity, sensitivity and prognosis. Therefore, DILI diagnosis ... -
Lymphocyte Profile and Immune Checkpoint Expression in Drug-Induced Liver Injury: An Immunophenotyping Study
Cueto-Sánchez, Alejandro; Niu, Hao; Del Campo-Herrera, Enrique; Robles-Díaz, María Mercedes; Sanabria-Cabrera, Judith Adriana
; Ortega-Alonso, Aida; García-Cortés, Miren
; González-Grande, Rocío; Jiménez-Pérez, Miguel
; Ruiz-Cabello, Francisco; Andrade-Bellido, Raúl Jesús
; Lucena-González, María Isabel
[et al.] (Wiley, 2021-09-20)
The identification of specific HLA risk alleles in drug-induced liver injury (DILI) points toward an important role of the adaptive immune system in DILI development. In this study, we aimed to corroborate the role of an ... -
Microbiota diversity in nonalcoholic fatty liver disease and in drug-induced liver injury
Rodriguez-Diaz, Cristina; Taminiau, Bernard; García-García, Alberto; Cueto-Sánchez, Alejandro; Robles-Díaz, María Mercedes; Ortega-Alonso, Aida; Martín-Reyes, Flores; Daube, Georges; Sanabria-Cabrera, Judith Adriana
; Jiménez-Pérez, Miguel
; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
; García Fuentes, Eduardo; García-Cortés, Miren
[et al.] (Elsevier, 2022-08)
The gut microbiota could play a significant role in the progression of nonalcoholic fatty liver disease (NAFLD); however, its relevance in drug-induced liver injury (DILI) remains unexplored. Since the two hepatic disorders ... -
Papel del sistema inmune y la microbiota intestinal en el daño hepático inducido por fármacos. Búsqueda de nuevos biomarcadores.
Cueto-Sánchez, Alejandro (UMA Editorial, 2023)El daño hepático inducido por fármacos (DILI) es una condición infrecuente, pero puede tener consecuencias graves para los pacientes, ya que puede resultar en fallo hepático fulminante. El mecanismo subyacente de DILI no ...