Listar por autor "Serrano, Antonia"
Mostrando ítems 1-19 de 19
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Behavioral traits predicting cocaine-conditioned place reference in mice: role of anxiety adn the basolateral amygdala
Ladrón de Guevara-Miranda, David; Pavón, Francisco Javier; Serrano, Antonia; Rivera, Patricia; Estivill-Torrús, Guillermo; Suárez, Juan; Rodriguez-de-Fonseca, Fernando; Santin-Nuñez, Luis Javier
; Castilla-Ortega, Maria Estela[et al.] (2016-07-13)
Aims. The individual susceptibility to cocaine addiction, a factor of interest in the understanding and prevention of this disorder, may be predicted by certain behavioral traits. However, these are not usually taken into ... -
Chronic ethanol induces morpohological changes on hippocampal microglia, which are reverted by pharmacological blockade of faah with urb597
Fernández-Arjona, María del Mar; Rivera, Patricia; Silva-Peña, Daniel; Blanco, Eduardo; Vargas, Antonio; López-Ávalos, María Dolores; Grondona, Jesús M; Serrano, Antonia; Pavón, Francisco Javier; Rodriguez-de-Fonseca, Fernando; Suárez, Juan[et al.] (2018-11-29)
Here, we evaluated the pharmacological effects of fatty-acid amide-hydrolase (FAAH) inhibitor URB597 (0.3 mg/kg), oleoylethanolamide (OEA, 10 mg/kg), arachidonoylethanolamide (AEA, 10 mg/kg), the CB1 receptor agonist ACEA ... -
Endocrine and Metabolic impact of oral ingestion of a carob-pod derived natural syrup containing D-Pinitol: potential use as a novel sweetener in diabetes
Navarro, Juan Antonio; Decara, Juan; Dina, Medina; Tovar, Ruben; López-Gambero, Antonio; Pavón, Francisco Javier; Serrano, Antonia; de Ceglia, Marialuisa; Sanjuan, Carlos; Rodriguez-de-Fonseca, Fernando; Baixeras-Llano, Elena[et al.] (EMBO, 2022)
The use of added sugars or non-nutritive sweeteners in processed foods and soft drinks are being blamed for multiple complications associated with obesity and diabetes. High fructose content contributes to obesity and liver ... -
Enhancing adult hippocampal neurogenesis with lysophosphatidic acid: a proposal for erasing cocaine contextual memory
Ladrón de Guevara-Miranda, David; Moreno-Fernández, Román D.; Gil Rodríguez, Sara; Rosell-del-Valle, Cristina; Estivill-Torrús, Guillermo; Serrano, Antonia; Pavón, Francisco Javier; Rodriguez-de-Fonseca, Fernando; Santin-Nuñez, Luis Javier; Castilla-Ortega, Maria Estela[et al.] (2018-06-28)
Stimulating adult hippocampal neurogenesis (AHN) has been uncovered as a promising approach in the manipulation of retrograde memories. This work aims to study whether increasing AHN with lysophosphatidic acid (LPA, an ... -
Galanin (1-15) and escitalopram combination in rats reduces alcohol consumption in the ethanol self-administration test and improves escitalopram effects in the forced swimming test.
Cantero García, Noelia; Flores-Burgess, Antonio; Ladrón de Guevara-Miranda, David; Serrano, Antonia; Garcia-Duran, Laura; Puigcerver-Martinez, Araceli; Fuxe, Kjell; Narváez, José Ángel; Santin-Nuñez, Luis Javier; Díaz-Cabiale, Zaida; Millon-Peñuela, Carmelo[et al.] (2022-07-12)
Recently, we described that Galanin(1-15)[GAL(1-15)] enhanced Escitalopram(ESC) effectiveness in depression symptoms. Moreover GAL(1-15) induces a substantial reduction in alcohol consumption. To investigate the effect of ... -
Galanin n-terminal fragment (1-15) decreases the voluntary alcohol intake in rats
Millon-Peñuela, Carmelo; Flores-Burgess, Antonio; Castilla-Ortega, Maria Estela; Gago-Calderon, Belen; Serrano, Antonia; Sturla, Antonella; Garcia-Duran, Laura; Narváez, José Ángel; Fuxe, Kjell; Santin-Nuñez, Luis Javier; Díaz-Cabiale, Zaida[et al.] (2018-06-28)
Galanin (GAL) is involved in drug abuse and addiction including alcohol intake. In this work, we have analysed the role of the N-terminal GAL fragment (1-15) [GAL(1-15)] in voluntary ethanol consumption in rats using the ... -
Galanin N-terminal fragment (1− 15) reduces alcohol seeking and alcohol relapse in rats: Involvement of mesocorticolimbic system
Cantero-García, Noelia; Flores-Burgess, Antonio; Pineda-Gómez, Juan Pedro; Orio, Laura; Serrano, Antonia; Díaz-Cabiale, Zaida; Millon-Peñuela, Carmelo[et al.] (Elsevier, 2022)
Alcohol Use Disorder (AUD) is among the most prevalent mental illnesses, and due to the low efficacy of the current medication, it is essential to find new biological targets that could modulate alcohol consumption. Since ... -
Galanin N-terminal fragment (1−15) reduces alcohol seeking and alcohol relapse in rats: Involvement of mesocorticolimbic system
Cantero-García, Noelia; Flores-Burgess, Antonio; Pineda-Gómez, Juan Pedro; Orio, Laura; Serrano, Antonia; Díaz-Cabiale, Zaida; Millon-Peñuela, Carmelo[et al.] (Elsevier, 2022-09)
Alcohol Use Disorder (AUD) is among the most prevalent mental illnesses, and due to the low efficacy of the current medication, it is essential to find new biological targets that could modulate alcohol consumption. Since ... -
LPA1/3 receptor antagonist KI16425 as a novel treatment for the neurobehavioural effects of the ethanol
Ladrón de Guevara-Miranda, David; Sánchez-Marín, Laura; Alén, Francisco; Moreno-Fernández, Román D.; García-Fernández, Maria Inmaculada; Gil Rodríguez, Sara; Gavito, Ana; García-Marchena, Nuria; Pedraza-Benítez, Maria del Carmen; Pavón, Francisco Javier; Rodriguez-de-Fonseca, Fernando; Santin-Nuñez, Luis Javier; Serrano, Antonia; Castilla-Ortega, Maria Estela[et al.] (2017-07-24)
Aims. The lysophosphatidic acid (LPA) is an ubiquitous lysophospholipid that acts through G-protein coupled receptors (LPA1-6), and it is involved in the modulation of emotional and motivational behaviors. Recent literature ... -
Lysophosphatidic acid-induced increase in adult hippocampal neurogenesis facilitates the forgetting of cocaine-contextual memory
Ladrón de Guevara-Miranda, David; Moreno-Fernández, Román D.; Gil Rodríguez, Sara; Rosell-del-Valle, Cristina; Estivill-Torrús, Guillermo; Serrano, Antonia; Pavón, Francisco Javier; Rodriguez-de-Fonseca, Fernando; Santin-Nuñez, Luis Javier; Castilla-Ortega, Maria Estela[et al.] (Wiley, 2019)
Erasing memories of cocaine-stimuli associations might have important clinical implications for addiction therapy. Stimulating hippocampal plasticity by enhancing adult hippocampal neurogenesis (AHN) is a promising strategy ... -
More adult-born dentate gyrus neurons to weaken cocaine-related retrograde memories: an in vivo strategy employing exogenous lysophosphatidic acid
Ladrón de Guevara-Miranda, David; Moreno-Fernández, Román D.; Gil Rodríguez, Sara; Rosell-del-Valle, Cristina; Estivill-Torrús, Guillermo; Serrano, Antonia; Pavón, Francisco Javier; Rodriguez-de-Fonseca, Fernando; Santin-Nuñez, Luis Javier; Castilla-Ortega, Maria Estela[et al.] (2019-10-28)
The post-training enhancement of adult hippocampal neurogenesis (AHN) has been receiving growing interest as a potential method to manipulate retrograde memories. Recent hypothesis suggest that the addition of adult-born ... -
Plasma Amino Acid Concentrations in Patients with Alcohol and/or Cocaine Use Disorders and Their Association with Psychiatric Comorbidity and Sex
(IOAP-MPDI, 2022-05-14)(1) Background: Co-occurrence of mental and substance use disorders (SUD) is prevalent, but complicates their clinical courses, and specific biomarkers are required. Amino acids are altered in primary mental disorders; ... -
Plasma Concentrations of Neurofilament Light Chain Protein and Brain-Derived Neurotrophic Factor as Consistent Biomarkers of Cognitive Impairment in Alcohol Use Disorder
Requena-Ocaña, Nerea; Araos, Pedro; Serrano-Castro, Pedro Jesus; Flores-López, María; García-Marchena, Nuria; Oliver-Martos, Begoña; Ruiz-Ruiz, Juan Jesús; Gavito, Ana; Pavón, Francisco Javier; Serrano, Antonia; Mayoral, Fermín; Suarez-Perez, Juan; Rodriguez-de-Fonseca, Fernando[et al.] (IOAP-MDPI, 2023-01-07)
For a long time, Substance Use Disorders (SUDs) were not considered a component in the etiology of dementia. The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders introduced substance-induced ... -
Reduction of adult hippocampal neurogenesis modifies brain functional connectivity and enhances cocaine-seeking in mice
Castilla-Ortega, Maria Estela; Ladrón de Guevara-Miranda, David; Blanco-Calvo, Eduardo; Serrano, Antonia; Pedraz, María; Estivill-Torrús, Guillermo; Pavón, Francisco; Rodriguez-de-Fonseca, Fernando; Santin-Nuñez, Luis Javier[et al.] (2015-09-16)
Recently, adult hippocampal neurogenesis has been proposed as a putative neuroplastic mechanism involved in those behavioural processes. In this work, we studied the effect of the inhibition of adult hippocampal neurogenesis ... -
Sex Differences in Plasma Lysophosphatidic Acid Species in Patients with Alcohol and Cocaine Use Disorders
(IOAP-MPDI, 2022-04-30)Preclinical evidence suggests a main role of lysophosphatidic acid (LPA) signaling in drug addiction. Recently, we reported alterations in the plasma concentrations of LPA species in patients with alcohol use disorder ... -
The Combination of Galanin (1–15) and Escitalopram in Rats Suggests a New Strategy for Alcohol Use Disorder Comorbidity with Depression
Cantero-García, Noelia; Flores-Burgess, Antonio; Ladrón de Guevara-Miranda, David; Serrano, Antonia; Garcia-Duran, Laura; Puigcerver-Martinez, Araceli; Fuxe, Kjell; Narváez, José Ángel; Santin-Nuñez, Luis Javier; Díaz-Cabiale, Zaida; Millon-Peñuela, Carmelo[et al.] (Universidad de Málaga, 2022-07-25)
Alcohol use disorder (AUD) is highly prevalent, and over 50% of AUD patients also suffer major depressive disorders. Selective 5-HT reuptake inhibitors (SSRIs) can reduce rodent ethanol drinking but exert modest clinical ... -
Vascular Endothelial Growth Factor as a Potential Biomarker of Neuroinflammation and Frontal Cognitive Impairment in Patients with Alcohol Use Disorder
Requena-Ocaña, Nerea; Flores-López, María; Papaseit, Esther; García-Marchena, Nuria; Ruiz-Ruiz, Juan Jesús; Ortega-Pinazo, Jesús; Serrano, Antonia; Pavón-Morón, Francisco Javier; Farré, Magí; Suarez-Perez, Juan; Rodriguez-de-Fonseca, Fernando; Araos Gomez, Pedro[et al.] (IOAP-MPDI, 2022-04-20)
(1) Background: Alcohol Use Disorder (AUD) is associated with functional disruption of several brain structures that may trigger cognitive dysfunction. One of the mechanisms of alcohol-associated cognitive impairment has ...