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Bioactivity of food melanoidins is mediated by gut microbiota.
Pérez-Burillo, Sergio; Rajakaruna, Sumudu; Pastoriza, Silvia; Paliy, Oleg; Rufián-Henares, José Ángel (Elsevier, 2020)Melanoidins are an important component of the human diet (average consumption 10g/day), which escape gastrointestinal digestion and are fermented by the gut microbiota. In this paper melanoidins from different food sources ... -
Cultivar and Harvest Time of Almonds Affect Their Antioxidant and Nutritional Profile through Gut Microbiota Modifications
Delgado-Osorio, Adriana; Navajas Porras, Beatriz; Pérez-Burillo, Sergio; Hinojosa-Nogueira, Daniel; Toledano-Marín, Ángela; Pastoriza, Silvia; Paliy, Oleg; Rufián-Henares, José Ángel[et al.] (MDPI, 2024-01-09)Almonds are a rich source of beneficial compounds for human health. In this work, we assessed the influence of almond cultivars and harvest time on their morphological (length, width and thickness) and nutritional (ash, ... -
Dietary Fatty Acids Sustain the Growth of the Human Gut Microbiota
Agans, Richard; Gordon, Alex; Kramer, Denise Lynette; Pérez-Burillo, Sergio; Rufián-Henares, José Ángel; Paliy, Oleg[et al.] (American Society for Microbiology, 2018)While a substantial amount of dietary fats escape absorption in the human small intestine and reach the colon, the ability of resident microbiota to utilize these dietary fats for growth has not been investigated in detail. ... -
Dietary Melanoidins from Biscuits and Bread Crust Alter the Structure and Short-Chain Fatty Acid Production of Human Gut Microbiota.
Rajakaruna, Sumudu; Pérez-Burillo, Sergio; Kramer, Denise Lynette; Rufián-Henares, José Ángel; Paliy, Oleg (MDPI, 2022-06-22)Melanoidins are the products of the Maillard reaction between carbonyl and amino groups of macromolecules and are readily formed in foods, especially during heat treatment. In this study we utilized the three-stage Human ... -
Growth of Bifidobacterium species is inhibited by free fatty acids and bile salts but not by glycerides.
Pérez-Burillo, Sergio; Rajakaruna, Sumudu; Paliy, Oleg (AIMS Press, 2022-02-10)High-fat diets have been associated with lower gut and fecal abundances of genus Bifidobacterium. Here, we investigated whether commonly consumed dietary free fatty acids have any detrimental effect on the growth of B. ...