- RIUMA Principal
- Listar por autor
Listar por autor "Flores-López, María"
Mostrando ítems 1-8 de 8
-
Antipsychotic Medication Influences the Discriminative Value of Acylethanolamides as Biomarkers of Substance Use Disorder.
Herrera-Imbroda, Jesús; Flores-López, María; Requena-Ocaña, Nerea; Araos Gómez, Pedro Fernando; Ropero, Jessica; García-Marchena, Nuria; Bordallo Aragón, Antonio; Suárez-Pérez, Juan; Pavón-Morón, Francisco Javier; Serrano, Antonia; Mayoral Cleries, Fermín; Rodriguez-de-Fonseca, Fernando[et al.] (MDPI, 2023-05-27)Plasma acylethanolamides (NAEs), including the endocannabinoid anandamide (AEA), have been proposed as circulating biomarkers of substance use disorders. However, the concentration of these lipid transmitters might be ... -
Evaluación del sistema del ácido lisofosfatídico como potencial biomarcador en los trastornos por uso de alcohol y cocaína.
Flores-López, María (UMA Editorial, 2024)El consumo de sustancias psicoactivas es un problema de salud pública con repercusión a nivel mundial, especialmente el consumo de alcohol y cocaína, al ser dos de las sustancias por las que más se demanda asistencia en ... -
Plasma Amino Acid Concentrations in Patients with Alcohol and/or Cocaine Use Disorders and Their Association with Psychiatric Comorbidity and Sex
García-Marchena, Nuria; Marcos, Alberto; Flores-López, María; Moreno-Fernández, Mario; Requena-Ocaña, Nerea; Porras-Perales, Oscar; Torres-Galván, Sandra; Araos Gómez, Pedro Fernando; Serrano, Antonia; Muga, Roberto; Ruiz-Ruiz, Juan Jesús; Rodriguez-de-Fonseca, Fernando; Ambrosio, Emilio; Pavón-Morón, Francisco Javier[et al.] (IOAP-MPDI, 2022-05-14)(1) Background: Co-occurrence of mental and substance use disorders (SUD) is prevalent, but complicates their clinical courses, and specific biomarkers are required. Amino acids are altered in primary mental disorders; ... -
Plasma Concentrations of High Mobility Group Box 1 Proteins and Soluble Receptors for Advanced Glycation End-Products Are Relevant Biomarkers of Cognitive Impairment in Alcohol Use Disorder: A Pilot Study.
Rodriguez-de-Fonseca, Fernando; Medina-Paz, Francisco; Sapozhnikov, Mira; Hurtado-Guerrero, Isaac; Rubio-Lamia, Leticia Olga; Martín-de-las-Heras, Stella; Requena-Ocaña, Nerea; Flores-López, María; Fernández-Arjona, María del Mar; Rivera, Patricia; Serrano, Antonia; Serrano-Castro, Pedro Jesús; Zapico, Sara C.; Suárez-Pérez, Juan[et al.] (MDPI (Toxics), 2024)Alcohol use disorder (AUD) is a major component in the etiology of cognitive decline and dementia. Underlying mechanisms by which long-term alcohol abuse causes cognitive dysfunction include excessive oxidative stress and ... -
Plasma Concentrations of Lysophosphatidic Acid and Autotaxin in Abstinent Patients with Alcohol Use Disorder and Comorbid Liver Disease.
Flores-López, María; García-Marchena, Nuria; Pavón-Morón, Francisco Javier; Lara, Estrella; Porras Perales, Óscar; Araos, Pedro; Requena-Ocaña, Nerea; Torres-Galván, Sandra; Mañas-Padilla, María del Carmen; Rubio, Gabriel; Suárez-Pérez, Juan; Santín-Núñez, Luis Javier; Rodriguez-de-Fonseca, Fernando; Castilla-Ortega, María Estela; García-Fernández, María Inmaculada; Serrano, Antonia[et al.] (2021-09-13)Lysophosphatidic acid (LPA) is an endogenous lysophospholipid and a bioactive lipid that is synthesized by the enzyme autotaxin (ATX). The ATX-LPA axis has been associated with cognitive dysfunction and inflammatory diseases, ... -
Plasma Concentrations of Neurofilament Light Chain Protein and Brain-Derived Neurotrophic Factor as Consistent Biomarkers of Cognitive Impairment in Alcohol Use Disorder
Requena-Ocaña, Nerea; Araos Gómez, Pedro Fernando; Serrano-Castro, Pedro Jesús; Flores-López, María; García-Marchena, Nuria; Oliver-Martos, Begoña; Ruiz-Ruiz, Juan Jesús; Gavito, Ana L.; Pavón-Morón, Francisco Javier; Serrano, Antonia; Mayoral Cleries, Fermín; Suárez-Pérez, Juan; Rodriguez-de-Fonseca, Fernando[et al.] (IOAP-MDPI, 2023-01-07)For a long time, Substance Use Disorders (SUDs) were not considered a component in the etiology of dementia. The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders introduced substance-induced ... -
Sex Differences in Plasma Lysophosphatidic Acid Species in Patients with Alcohol and Cocaine Use Disorders
Flores-López, María; García-Marchena, Nuria; Araos Gómez, Pedro Fernando; Requena-Ocaña, Nerea; Porras-Perales, Oscar; Torres-Galván, Sandra; Suárez-Pérez, Juan; Pizarro Lozano, Nieves; De la Torre, Rafael; Rubio, Gabriel; Ruiz-Ruiz, Juan Jesús; Rodriguez-de-Fonseca, Fernando; Serrano, Antonia; Pavón-Morón, Francisco Javier[et al.] (IOAP-MPDI, 2022-04-30)Preclinical evidence suggests a main role of lysophosphatidic acid (LPA) signaling in drug addiction. Recently, we reported alterations in the plasma concentrations of LPA species in patients with alcohol use disorder ... -
Vascular Endothelial Growth Factor as a Potential Biomarker of Neuroinflammation and Frontal Cognitive Impairment in Patients with Alcohol Use Disorder
Requena-Ocaña, Nerea; Flores-López, María; Papaseit, Esther; García-Marchena, Nuria; Ruiz-Ruiz, Juan Jesús; Ortega-Pinazo, Jesús; Serrano, Antonia; Pavón-Morón, Francisco Javier; Farré, Magí; Suárez-Pérez, Juan; Rodriguez-de-Fonseca, Fernando; Araos Gómez, Pedro Fernando[et al.] (IOAP-MPDI, 2022-04-20)(1) Background: Alcohol Use Disorder (AUD) is associated with functional disruption of several brain structures that may trigger cognitive dysfunction. One of the mechanisms of alcohol-associated cognitive impairment has ...