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Listar por autor "Pérez-Burillo, Sergio"
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An extended reconstruction of human gut microbiota metabolism of dietary compounds.
Blasco, Telmo; Pérez-Burillo, Sergio; Balzerani, Francesco; Hinojosa Nogueira, Daniel; Lerma Aguilera, Alberto; Pastoriza, Silvia; Cendoya, Xabier; Rubio, Ángel; Gosalbes, María José; Jiménez Hernández, Nuria; Francino, María Pilar; Apaolaza, Íñigo; Rufián-Henares, José Ángel; Planes, Francisco Javier[et al.] (Springer Nature, 2021-08-05)Understanding how diet and gut microbiota interact in the context of human health is a key question in personalized nutrition. Genome-scale metabolic networks and constraint-based modeling approaches are promising to ... -
Bioactivity of food melanoidins is mediated by gut microbiota.
Pérez-Burillo, Sergio; Rajakaruna, Sumudu; Pastoriza, Silvia; Paliy, Oleg; Rufián-Henares, José Ángel (Elsevier, 2020)Melanoidins are an important component of the human diet (average consumption 10g/day), which escape gastrointestinal digestion and are fermented by the gut microbiota. In this paper melanoidins from different food sources ... -
BN-BacArena: Bayesian network extension of BacArena for the dynamic simulation of microbial communities.
Blasco, Telmo; Balzerani, Francesco; Valcárcel, Luis V; Larrañaga, Pedro; Bielza, Concha; Francino, María Pilar; Rufián-Henares, José Ángel; Planes, Francisco Javier; Pérez-Burillo, Sergio[et al.] (Oxford University Press, 2024-04-30)Motivation Simulating gut microbial dynamics is extremely challenging. Several computational tools, notably the widely used BacArena, enable modeling of dynamic changes in the microbial environment. These methods, however, ... -
Cultivar and Harvest Time of Almonds Affect Their Antioxidant and Nutritional Profile through Gut Microbiota Modifications
Delgado-Osorio, Adriana; Navajas Porras, Beatriz; Pérez-Burillo, Sergio; Hinojosa-Nogueira, Daniel; Toledano-Marín, Ángela; Pastoriza, Silvia; Paliy, Oleg; Rufián-Henares, José Ángel[et al.] (MDPI, 2024-01-09)Almonds are a rich source of beneficial compounds for human health. In this work, we assessed the influence of almond cultivars and harvest time on their morphological (length, width and thickness) and nutritional (ash, ... -
Development of a food composition database of different food contaminants CONT11 and estimation of dietary exposure in children of southern Spain
Hinojosa-Nogueira, Daniel; Muros, José J.; Navajas Porras, Beatriz; Delgado-Osorio, Adriana; Pérez-Burillo, Sergio; Pastoriza, Silvia; Rufián-Henares, José Ángel[et al.] (Elsevier, 2023-05-26)Increasing food security is one of the Sustainable Development Goals. One of the main risks in food is the increase in food contaminants. Processing methods, such as the addition of additives or heat treatment, influence ... -
Dietary Fatty Acids Sustain the Growth of the Human Gut Microbiota
Agans, Richard; Gordon, Alex; Kramer, Denise Lynette; Pérez-Burillo, Sergio; Rufián-Henares, José Ángel; Paliy, Oleg[et al.] (American Society for Microbiology, 2018)While a substantial amount of dietary fats escape absorption in the human small intestine and reach the colon, the ability of resident microbiota to utilize these dietary fats for growth has not been investigated in detail. ... -
Dietary Melanoidins from Biscuits and Bread Crust Alter the Structure and Short-Chain Fatty Acid Production of Human Gut Microbiota.
Rajakaruna, Sumudu; Pérez-Burillo, Sergio; Kramer, Denise Lynette; Rufián-Henares, José Ángel; Paliy, Oleg (MDPI, 2022-06-22)Melanoidins are the products of the Maillard reaction between carbonyl and amino groups of macromolecules and are readily formed in foods, especially during heat treatment. In this study we utilized the three-stage Human ... -
Effect of a Triterpenoid-Rich Olive Oil on Chronic Kidney Disease in an Experimental Model of Diabetes Mellitus
De-la-Cruz-Cortés, José Pedro; Osuna-Esteban, Laura; Rodríguez-Pérez, María Dolores
; Ortega-Hombrados, Laura; Sánchez Tévar, Ana María; Martín Aurioles, Esther; Fernández-Prior, María África; Pérez-Burillo, Sergio; Espejo-Calvo, Juan Antonio; González-Correa, José Antonio
[et al.] (MDPI, 2024-08-21)
The aim of this study was to assess the effect of triterpenoids on the development of diabetic nephropathy in an experimental model of diabetes mellitus. For this purpose, a destoned and dehydrated olive oil (DDOO) was ... -
Effect of brewing time and temperature on antioxidant capacity and phenols of white tea: relationship with sensory properties
Pérez-Burillo, Sergio; Gimenez, Rafael; Rufián-Henares, José Ángel; Pastoriza, Silvia (Elsevier, 2018)White tea is highly consumed due to its sensory properties and health benefits, although most scientific reports don’t include the analysis of both properties. Therefore, the objective of the present study was to unravel ... -
Effect of food thermal processing on the composition of the gut microbiota
Pérez-Burillo, Sergio; Pastoriza, Silvia; Jiménez Hernández, Nuria; D'Auria, Giuseppe; Francino, Maria Pilar; Rufián-Henares, José Ángel; Francino[et al.] (American Chemical Society, 2018)Cooking modifies food composition due to chemical reactions. Additionally, food composition shapes the human gut microbiota. Thus, the objective of this research was to unravel the effect of different food cooking methods ... -
Effect of in vitro digestion and fermentation on antioxidant capacity of weight loss foods and Maillard reaction products content
Pérez-Burillo, Sergio; Hinojosa-Nogueira, Daniel; Rufián-Henares, José Ángel; Pastoriza, Silvia (Elsevier, 2023-02-27)Cereal snacks and meal replacement shakes are gaining popularity as part of a low-calorie diet. However, some concerns have been risen in relation to their nutrient content and industrial processing. Here we analyzed 74 ... -
Effect of roasting conditions on cocoa bioactivity and gut microbiota modulation.
Maldonado-Mateus, Lida Yaneth; Pérez-Burillo, Sergio; Lerma-Aguilera, Alberto; Hinojosa Nogueira, Daniel; Ruíz-Pérez, Sonia; Gosalbes, María José; Francino, Maria Pilar; Rufián-Henares, José Ángel; Pastoriza, Silvia[et al.] (Royal Society of Chemistry, 2021)Cocoa is a highly consumed food with beneficial effects on human health. Cocoa roasting has an important influence on its sensory and nutritional characteristics; therefore, roasting could also play a role in cocoa ... -
Effects of different foods and cooking methods on the gut microbiota: an in vitro approach.
Lerma-Aguilera, Alberto; Pérez-Burillo, Sergio; Navajas Porras, Beatriz; León, Daniel; Ruíz-Pérez, Sonia; Pastoriza, Silvia; Jiménez Hernández, Nuria; Cämmerer, Bettina-Maria; Rufián-Henares, José Ángel; Gosalbes, María José; Francino, María Pilar[et al.] (Frontiers, 2024-01-08)To support personalized diets targeting the gut microbiota, we employed an in vitro digestion-fermentation model and 16S rRNA gene sequencing to analyze the microbiota growing on representative foods of the Mediterranean and ... -
Evaluating the effects of a standardized polyphenol mixture extracted from poplar-type propolis on healthy and diseased human gut microbiota.
Garzarella, Emanuele Ugo; Navajas Porras, Beatriz; Pérez-Burillo, Sergio; Ullah, Hammad; Esposito, Cristina; Santarcangelo, Cristina; Hinojosa Nogueira, Daniel; Pastoriza, Silvia; Zaccaria, Vincenzo; Xiao, Jianbo; Rufián-Henares, José Ángel; Daglia, Maria[et al.] (Elsevier, 2022-04)Introduction: A large body of evidence suggests that propolis exerts antioxidant, anti-inflammatory, and antimicrobial activities, mostly ascribed to its polyphenol content. Growing evidence suggests that propolis ... -
Evaluation of Polyphenol Intake in Pregnant Women from South-Eastern Spain and the Effect on Anthropometric Measures at Birth and Gestational Age
Hinojosa-Nogueira, Daniel; Romero-Molina, Desirée; Gonzalez Alzaga, Beatriz; Giménez-Asensio, María José; Hernández, Antonio F.; Navajas Porras, Beatriz; Delgado-Osorio, Adriana; Gómez-Martín, Antonio; Pérez-Burillo, Sergio; Pastoriza, Silvia; Lacasaña, Marina; Rufián-Henares, José Ángel[et al.] (MDPI, 2024-09-13)During pregnancy, controlling nutrition is crucial for the health of both mother and foetus. While polyphenols have positive health effects, some studies show harmful outcomes during pregnancy. This study evaluated polyphenol ... -
Extending PROXIMAL to predict degradation pathways of phenolic compounds in the human gut microbiota.
Balzerani, Francesco; Blasco, Telmo; Pérez-Burillo, Sergio; Valcárcel, Luis V; Hassoun, Soha; Planes, Francisco Javier[et al.] (Springer Nature, 2024-05-27)Despite significant advances in reconstructing genome-scale metabolic networks, the understanding of cellular metabolism remains incomplete for many organisms. A promising approach for elucidating cellular metabolism is ... -
Growth of Bifidobacterium species is inhibited by free fatty acids and bile salts but not by glycerides.
Pérez-Burillo, Sergio; Rajakaruna, Sumudu; Paliy, Oleg (AIMS Press, 2022-02-10)High-fat diets have been associated with lower gut and fecal abundances of genus Bifidobacterium. Here, we investigated whether commonly consumed dietary free fatty acids have any detrimental effect on the growth of B. ... -
In vitro batch fermentation protocol to study the contribution of food to gut microbiota composition and functionality
Pérez-Burillo, Sergio; Molino, Silvia; Navajas Porras, Beatriz; Valverde Moya, Álvaro; Hinojosa Nogueira, Daniel; López Maldonado, Alicia; Pastoriza, Silvia; Rufián-Henares, José Ángel[et al.] (Springer Nature, 2021)Knowledge about the effect of foods on gut microbiota composition and functionality is expanding. To isolate the effect of single foods and/or single nutrients (i.e. fibre, polyphenols), this protocol describes an in vitro ... -
Potential probiotic salami with dietary fiber modulates metabolism and gut microbiota in a human intervention study.
Pérez-Burillo, Sergio; Pastoriza, Silvia; Gironés, Amadeo; Avellaneda, Antonio; Francino, Maria Pilar; Rufián-Henares, José Ángel[et al.] (Elsevier, 2020)A human intervention in 24 healthy volunteers was performed to test the potential health benefits of a fermented salami with a probiotic Lactobacillus rhamnosus HN001 and added citrus fiber. Anthropometric measurements and ... -
Prediction of degradation pathways of phenolic compounds in the human gut microbiota through enzyme promiscuity methods.
Balzerani, Francesco; Hinojosa-Nogueira, Daniel; Cendoya, Xabier; Blasco, Telmo; Pérez-Burillo, Sergio; Apaolaza, Íñigo; Francino, María Pilar; Rufián-Henares, José Ángel; Planes, Francisco Javier[et al.] (Springer Nature, 2022)The relevance of phenolic compounds in the human diet has increased in recent years, particularly due to their role as natural antioxidants and chemopreventive agents in different diseases. In the human body, phenolic ...