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Listar por autor "López-Aranda, Manuel Francisco"
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Activation of caspase-3 pathway by expression of sGαi2 protein in BHK cells.
López-Aranda, Manuel Francisco; Navarro-Lobato, Irene; López-Téllez, Juan Félix; Blanco-Calvo, Eduardo; Masmudi-Martín, Mariam; Khan, Zafaruddin[et al.] (Elsevier, 2008)Treatment with dopamine and other dopamine D2 receptor agonists has been shown to induce cell death through activation of caspase-3 pathway. However, initial step that leads to the activation of caspase-3 in D2 receptor-mediated ... -
Brain areas interconnected to ventral pathway circuitsare independently able to induce enhancement in objectrecognition memory and cause reversal in object recognitionmemory deficit.
Masmudi-Martin, Mariam; Navarro-Lobato, Irene; López-Aranda, Manuel Francisco; Quirós-Ortega, María Elena; Carretero-Rey, Marta; García-Garrido, María F.; López-Téllez, Juan Félix; Jiménez Recuerda, Inmaculada; Muñoz-de-León-López, Cristina; Khan, Zafaruddin[et al.] (Wiley, 2024)Ventral pathway circuits are constituted by the interconnected brain areas that are distributed throughout the brain. These brain circuits are primarily involved in processing of object related information in brain. However, ... -
Localization of the GoLoco motif carrier regulator of G-protein signalling 12 and 14 proteins in monkey and rat brain
López-Aranda, Manuel Francisco; Acevedo, Maria J.; Carballo, Francisco J.; Gutiérrez-Pérez, Antonia; Khan, Zafaruddin (WILEY, 2006-06)Regulator of G-protein signalling (RGS)12 and -14 proteins possess the RGS domain, Ras-binding domains and the GoLoco motif. Emerging evidence suggests that these proteins are involved in several cellular functions in ... -
Long-term reprogramming of primed microglia after moderate inhibition of CSF1R signaling.
León-Rodríguez, Ana; Mateos-Grondona, Jesús; Marín Wong, Sonia; López-Aranda, Manuel Francisco; López-Ávalos, María Dolores (Wiley, 2024)In acute neuroinflammation, microglia activate transiently, and return to a resting state later on. However, they may retain immune memory of such event, namely priming. Primed microglia are more sensitive to new stimuli ... -
Promotion of structural plasticity in area V2 of visual cortex prevents against object recognition memory deficits in aging and Alzheimer's disease rodents.
Navarro-Lobato, Irene; Masmudi-Martín, Mariam; López-Aranda, Manuel Francisco; López-Téllez, Juan Félix; Delgado, Gloria; Granados-Durán, Pablo; Gaona-Romero, Celia; Carretero-Rey, Marta; Posadas, Sinforiano; Quirós-Ortega, María Elena; Khan, Zafaruddin[et al.] (Wolters Kluwer Medknow, 2023-11-08)Memory deficit, which is often associated with aging and many psychiatric, neurological, and neurodegenerative diseases, has been a challenging issue for treatment. Up till now, all potential drug candidates have failed ...