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Listar por autor "Boughanem Lakhal, Hatim"
Mostrando ítems 1-4 de 4
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8-oxoguanine DNA glycosylase 1 upregulation as a risk factor for obesity and colorectal cancer
Pilo, Jesús; García-Flores, Libia Alejandra; Clemente-Postigo, María Mercedes; Arranz-Salas, Isabel María; Alcaide, Julia; Ramos-Fernandez, Maria; Lozano-Castro, José; Boughanem Lakhal, Hatim; Kompella, Pallavi; Macías-González, Manuel[et al.] (MDPI, 2023-03-13)DNA damage has been extensively studied as a potentially helpful tool in assessing and preventing cancer, having been widely associated with the deregulation of DNA damage repair (DDR) genes and with an increased risk of ... -
Comprehensive landscape of DNA methylation in colorectal cancer
Boughanem Lakhal, Hatim (UMA Editorial, 2022)Colorectal cancer (CRC) is already the second leading cause of cancer deaths worldwide, being the third most commonly diagnosed malignancy in developed countries. CRC typically arises as a consequence of the accumulation ... -
Epigenetic changes in the metabolically healthy obese: A case-control versus a prospective study
Linares-Pineda, Teresa María; Boughanem Lakhal, Hatim; Gutiérrez Repiso, Carolina; Macías-González, Manuel; Andrés-León, Eduardo; Rojo-Martínez, Gemma; Valdés, Sergio[et al.] (Wiley, 2022-03-28)Obesity has become a worldwide health problem, in which latest statistics reported an increased trend over the last years. Accordingly, long-term obesity is involved in an increased risk of developing several metabolic ... -
The emergent role of mitochondrial RNA modifications in metabolic alterations
Boughanem Lakhal, Hatim; Böttcher, Yvonne; Tomé-Carneiro, João; López de las Hazas, María-Carmen; Dávalos, Akin Cayir; Macías-González, Manuel[et al.] (Wiley, 2022-07-25)Mitochondrial epitranscriptomics refers to the modifications occurring in all the different RNA types of mitochondria. Although the number of mitochondrial RNA modifications is less than those in cytoplasm, substantial ...