Listar por autor "Do Huynh, Kelly"
Mostrando ítems 1-7 de 7
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Amyloid-b seeding and propagation processes in a hAb-KI model of Alzheimer's disease
Trujillo-Estrada, Laura Isabel
; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Cheung, Alwin; Pham Tran, Janine; Núñez-Díaz, Cristina; Forner, Stefania; Martini, Alessandra C.; Da Cunha, Celia; Shahnawaz, Mohammad; Soto, Claudio; Moreno-González, Inés; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (2020-12-17)
Recent evidence indicates that Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like process. Several studies using FAD animal models have demonstrated that ... -
Dataset seeding paper JAL.
Andreo-López, Juana; Núñez-Díaz, Cristina; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Da Cunha, Celia; Cantero-Molina, Francisco; Campos-Moreno, Cynthia; Zimbone, Stefania; Bellia, Francesco; Giuffrida, Maria Laura; Trujillo-Estrada, Laura Isabel; García-León, Juan Antonio; Bettinetti-Luque, Miriam; Gámez, Nazaret; Valdés, Catalina; Morales, Rodrigo; Forner, Stefania; Martini, Alessandra C.; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (Universidad de Málaga, 2023-11-24)
Este trabajo se centra en el estudio de la propagación de la patología amiloidea en diferentes modelos animales para la Enfermedad de Alzheimer (EA). Los resultados sugieren que existen diversos factores que modulan este ... -
Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology.
(Springer Nature, 2021-04-23)The majority of Alzheimer’s disease (AD) cases are late-onset and occur sporadically, however most mouse models of the disease harbor pathogenic mutations, rendering them better representations of familial autosomal-dominant ... -
Human and Mouse Alzheimer's Seeds Differentially Affect Amyloid Deposition and Microglia-Dependent Plaque Response in Aged Mice
Andreo-López, Juana; Núñez-Díaz, Cristina; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Da Cunha, Celia; Cantero-Molina, Francisco; Campos-Moreno, Cynthia; Zimbone, Stefania; Bellia, Francesco; Giuffrida, Maria Laura; Trujillo-Estrada, Laura Isabel; García-León, Juan Antonio; Bettinetti-Luque, Miriam; Gámez, Nazaret; Valdés, Catalina; Morales, Rodrigo; Forner, Stefania; Martini, Alessandra C.; Gutiérrez-Pérez, Antonia; LaFerla, Frank M.; Baglietto-Vargas, David[et al.] (Wiley, 2025-05-13)
Alzheimer's disease (AD) is a complex neurodegenerative proteinopathy in which Aβ and tau misfold and aggregate into entities that structurally unsettle native proteins, mimicking a prion-like or “seeding” process. These ... -
Human and mouse seeds differentially affect AB aggregation by modulating the inflammatory response.
Andreo-López, Juana; Cantero-Molina, Francisco; Bettinetti-Luque, Miriam; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Cheung, Alwin; Pham Tran, Janine; Da Cunha, Celia; Morales-Cabello, Mario; Fatuarte Juli, Ivan; Trujillo-Estrada, Laura Isabel; Núñez-Díaz, Cristina; Cadete-Martini, Alessandra; Forner, Stefania; LaFerla, Frank; Gutiérrez-Pérez, Antonia; Baglietto-Vargas, David[et al.] (2023)
Abstract text: Alzheimer’s Disease (AD) is a neurodegenerative proteinopathy in which Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prionlike process. These amyloid aggregation ... -
Human and mouse seeds differentially affect Aβ aggregation by modulating the inflammatory response
Andreo-López, Juana; Cantero-Molina, Francisco; Bettinetti-Luque, Miriam; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Cheung, Alwin; Pham Tran, Janine; Da Cunha, Celia; Trujillo-Estrada, Laura Isabel; Núñez-Díaz, Cristina; Cadete-Martini, Alessandra; Forner, Stefania; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (2023)
Background: Alzheimer’s Disease (AD) is a neurodegenerative proteinopathy in which Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like process. These amyloid aggregation ... -
The effect of different amyloid seeds and animal hosts on amyloid propagation in Alzheimer's Disease
Andreo-López, Juana; Cantero-Molina, Francisco; Bettinetti-Luque, Miriam; Do Huynh, Kelly; Thu Nguyen, Marie Minh; Cheung, Alwin; Pham Tran, Janine; Trujillo-Estrada, Laura Isabel; Núñez-Díaz, Cristina; Martini, Alessandra C.; Forner, Stefania; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (2022-07-13)
Abstract text: Alzheimer's Disease is a neurodegenerative proteinopathy in which recent evidence indicates that Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like ...