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Listar por autor "Antunes-Martins, Ana"
Mostrando ítems 1-3 de 3
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A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat
Perkins, James R; Antunes-Martins, Ana; Calvo, Margarita; Grist, John; Rust, Werner; Schmid, Ramona; Hildebrandt, Tobias; Kohl, Matthias; Orengo, Christine A.; McMahon, Stephen B; Bennett, David LH[et al.] (SAGE Publications, 2014-01-28)The past decade has seen an abundance of transcriptional profiling studies of preclinical models of persistent pain, predominantly employing microarray technology. In this study we directly compare exon microarrays to ... -
Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination
Fricker, Florence R; Antunes-Martins, Ana; Galino, Jorge; Paramsothy, Remi; La Russa, Federica; Perkins, James; Goldberg, Rebecca; Brelstaff, Jack; Zhu, Ning; McMahon, Stephen B; Orengo, Christine; Garratt, Alistair N; Birchmeier, Carmen; Bennett, David LH; Perkins[et al.] (Oxford University Press, 2013-07)Neuregulin 1 acts as an axonal signal that regulates multiple aspects of Schwann cell development including the survival and migration of Schwann cell precursors, the ensheathment of axons and subsequent elaboration of the ... -
PainNetworks: A web-based resource for the visualisation of pain related genes in the context of their network associations.
Perkins, James Richard; Lees, Jonathan; Antunes-Martins, Ana; Diboun, Ilhem; Mcmahon, Stephen B.; Bennett, David L. H.; Orengo, Christine A.[et al.] (IASP/Wolters Kluwer, 2013-08-11)We now know of hundreds of genes that have some association with pain. Several genes have been shown to alter pain sensitivity in humans, and can be found in the OMIM database. The Pain Gene Database gives details of genes ...