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Aggregate-Depleted Brain Fails to Induce Ab Deposition in a Mouse Model of Alzheimer’s Disease.
Duran-Aniotz, Claudia; Morales, Rodrigo; Moreno-González, Inés; Hu, Ping Ping; Fedynyshyn, Joseph; Soto, Claudio[et al.] (PLOS, 2014-02-12)Recent studies in animal models of Alzheimer’s disease (AD) show that amyloid-beta (Ab) misfolding can be transmissible; however, the mechanisms by which this process occurs have not been fully explored. The goal of this ...