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Listar por autor "Ruiz, Agustín"
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A Functional Pipeline of Genome-Wide Association Data Leads to Midostaurin as a Repurposed Drug for Alzheimer’s Disease
Esteban-Martos, Alvaro; Brokate-Llanos, Ana María; Real-Navarrete, Luis Miguel; Melgar-Locatelli, Sonia; De Rojas, Itziar; Castro-Zavala, Adriana; Bravo-Romero, María José
; Mañas-Padilla, María del Carmen; García-González, Pablo; Ruiz-Galdón, Maximiliano
; Pacheco-Sánchez, Beatriz; Polvillo, Rocío; Rodriguez-de-Fonseca, Fernando; González, Irene; Castilla-Ortega, María Estela
; Muñoz-Gómez, Manuel
; Rivera, Patricia; Reyes-Engel, Armando
; Ruiz, Agustín; Royo-Sánchez-Palencia, José Luis
[et al.] (MDPI, 2023)
Genome-wide association studies (GWAS) constitute a powerful tool to identify the different biochemical pathways associated with disease. This knowledge can be used to prioritize drugs targeting these routes, paving the ... -
Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1
Matesanz, Fuencisla; González-Pérez, Antonio; Lucas, Miguel; Sanna, Serena; Gayán, Javier; Urcelay, Elena; Zara, Ilenia; Pitzalis, Maristella; Cavanillas, María L; Arroyo, Rafael; Zoledziewska, Magdalena; Marrosu, Marisa; Fernández Fernández, Óscar; Leyva-Fernández, Laura; Alcina, Antonio; Fedetz, María; Moreno-Rey, Concha; Velasco, Juan; Real, Luis M.; Ruiz-Peña, Juan Luis; Cucca, Francesco; Ruiz, Agustín; Izquierdo, Guillermo; Matesanz[et al.] (Public Library of Science, 2012)Multiple Sclerosis (MS) is the most common progressive and disabling neurological condition affecting young adults in the world today. From a genetic point of view, MS is a complex disorder resulting from the combination ...