Listar por autor "Edwards, George"

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Impaired Peripheral Lymphatic Function and Cerebrospinal Fluid Outflow in a Mouse Model of Alzheimer's Disease

Kwon, Wu; Moreno-Gonzalez, Ines; Taylor-Presse, Kaithlyn; Edwards, George; Gamez, Nazaret; Calderon, Olivia; Zhu, Be; Velasquez, Francisco C; Soto, Claudio; Sevick-Muraca, Eva Marie; Taylor-Presse[et al.] (Sage Journals, 2019)

Cerebrospinal fluid (CSF) outflow from the brain occurs through absorption into the arachnoid villi and, more predominantly, through meningeal and olfactory lymphatics that ultimately drain into the peripheral lymphatics. ...
Peripheral delivery of neural precursor cells ameliorates parkinson’s disease-associated pathology

Edwards, George; Gámez, Nazaret; Armijo, Enrique; Kramm, Carlos; Morales, Rodrigo; Taylor-Presse, Kaithlyn; Schulz, Paul; Soto, Claudio; Moreno-González, Inés[et al.] (MDPI, 2019)

Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by loss of motor control due to a wide loss of dopaminergic neurons along the nigro-striatal pathway. Some of the mechanisms that contribute ...
Traumatic brain injury induces tau aggregation and spreading.

Edwards, George; Zhao, Jing; Dash, Pramod; Soto, Claudio; Moreno-González, Inés (Mary Ann Liebert Inc., 2020)

The misfolding and aggregation of tau protein into neurofibrillary tangles is the main underlying hallmark of tauopathies. Most tauopathies have a sporadic origin and can be associated with multiple risk factors. Traumatic ...