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Clinical characteristics and outcome of drug-induced liver injury in the older patients: from the young-old to the oldest-old
Weersink, Rianne A.; Alvarez-Alvarez, Ismael; Medina-Cáliz, Inmaculada; Sanabria-Cabrera, Judith Adriana
; Robles-Díaz, María Mercedes
; Ortega-Alonso, Aida; García-Cortés, Miren
; Bonilla, Elvira; Niu, Hao; Soriano, German; Jiménez-Pérez, Miguel
; Hallal, Hacibe; Blanco, Sonia; Kaplowitz, Neil; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
[et al.] (Wiley, 2020-11-11)
Old patients with hepatotoxicity have been scarcely studied in idiosyncratic drug-induced liver injury (DILI) cohorts. We sought for the distinctive characteristics of DILI in older patients across age groups. A total of ... -
Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry
Stephens, Camilla; Robles-Díaz, María Mercedes; Medina-Cáliz, Inmaculada
; García-Cortés, Miren
; Ortega-Alonso, Aida; Sanabria-Cabrera, Judith Adriana
; González-Jiménez, Andrés; Alvarez-Alvarez, Ismael; Slim, Mahmoud; Jiménez-Pérez, Miguel
; González-Grande, Rocío; Fernández, M. Carmen; Casado, Marta; Soriano, German; Roman, Eva; Hallal, Hacibe; Romero-Gomez, Manuel; Castiella, Agustin; Conde, Isabel; Prieto, Martin; Moreno-Planas, José María; Giraldez, Alvaro; Moreno-Sanfiel, J Miguel; Kaplowitz, Neil; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
[et al.] (Elsevier, 2021-02-01)
Background & aims: Prospective drug-induced liver injury (DILI) registries are important sources of information on idiosyncratic DILI. We aimed to present a comprehensive analysis of 843 patients with DILI enrolled into ... -
Herbal and dietary supplement-induced liver injuries in the spanish DILI registry
Medina-Cáliz, Inmaculada; García-Cortés, Miren
; González-Jiménez, Andrés; Cabello-Porras, María Rosario
; Robles-Díaz, María Mercedes
; Sanabria-Cabrera, Judith Adriana
; Sanjuan-Jimenez, Rocio; Ortega-Alonso, Aida; García-Muñoz, Beatriz; Moreno, Inmaculada; Jiménez-Pérez, Miguel
; Fernández, M. Carmen; Ginés, Pere; Prieto, Martin; Conde, Isabel; Hallal, Hacibe; Soriano, German; Roman, Eva; Castiella, Agustin; Blanco-Reina, Encarnación
; Montes, Maria R; Quiros-Cano, Marta; Martín-Reyes, Flores; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
[et al.] (Elsevier, 2018-01)
There have been increasing reports of liver injury associated with use of herbal and dietary supplements.We collected and analyzed data on demographic and clinical features, along with biochemical parameters, of 32 patients ... -
Role of chemical structures and the 1331T>C bile salt export pump polymorphism in idiosyncratic drug-induced liver injury
Ulzurrun, Eugenia; Stephens, Camilla; Crespo, Esperanza; Ruiz-Cabello, Francisco; Ruiz-Nuñez, Julia; Saenz-López, Pablo; Moreno-Herrera, Inmaculada; Robles-Díaz, María Mercedes; Hallal, Hacibe; Moreno-Planas, José María; Cabello-Porras, María Rosario
; Lucena-González, María Isabel
; Andrade-Bellido, Raúl Jesús
[et al.] (WILEY, 2013-04)
Background & aims: Several pharmaceutical compounds have been shown to exert inhibitory effects on the bile salt export pump (BSEP) encoded by the ABCB11 gene. We analysed the combined effect on drug-induced liver injury ...