Listar por autor "Castro-Zavala, Adriana"
Mostrando ítems 1-10 de 10
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A behavioral test battery only reveals Sex-Specific Differences in Spatial Reference Memory Acquisition in C57BL/6JRj Mice
Melgar-Locatelli, Sonia; Mañas-Padilla, María del Carmen; Gavito, Ana Luisa; Rivera-González, Patricia; Rodríguez-Pérez, Celia; Castilla-Ortega, María Estela
; Castro-Zavala, Adriana[et al.] (2024-01-15)
Sex disparities in declarative and spatial memory exist in humans, favoring either gender depending on the task. This trend is observed in rats but less so in mice. In our study with C57BL/6JRj mice, we conducted various ... -
A Functional Pipeline of Genome-Wide Association Data Leads to Midostaurin as a Repurposed Drug for Alzheimer’s Disease
Esteban-Martos, Alvaro; Brokate-Llanos, Ana María; Real-Navarrete, Luis Miguel; Melgar-Locatelli, Sonia; De Rojas, Itziar; Castro-Zavala, Adriana; Bravo-Romero, María José; Mañas-Padilla, María del Carmen; García-González, Pablo; Ruiz-Galdón, Maximiliano; Pacheco-Sánchez, Beatriz; Polvillo, Rocío; Rodriguez-de-Fonseca, Fernando; González, Irene; Castilla-Ortega, María Estela; Muñoz-Gómez, Manuel; Rivera, Patricia; Reyes-Engel, Armando; Ruiz, Agustín; Royo-Sánchez-Palencia, José Luis[et al.] (MDPI, 2023)
Genome-wide association studies (GWAS) constitute a powerful tool to identify the different biochemical pathways associated with disease. This knowledge can be used to prioritize drugs targeting these routes, paving the ... -
Dataset for: A persistent increase in gut permeability correlates with emotional dysregulation following maternal separation in male and female mice.
Castro-Zavala, Adriana; Nieto-Nieves, Ana; Melgar-Locatelli, Sonia; Medina-Rodríguez, Lidia; Mañas-Padilla, María del Carmen; Castilla-Ortega, María Estela[et al.] (Universidad de Málaga, 2025-04-03)
Early life stress (ELS) can significantly influence vulnerability to the development of psychiatric disorders in adulthood. One of the most widely used preclinical models for investigating ELS is maternal separation with ... -
Diet enriched with high-phenolic cocoa potentiates hippocampal brain-derived neurotrophic factor expression and neurogenesis in healthy adult micewith subtle effects on memory
Melgar-Locatelli, Sonia; Mañas-Padilla, María del Carmen; Castro-Zavala, Adriana; Rivera, Patricia; Razola-Díaz, María del Carmen; Monje, Francisco J; Rodríguez-Pérez, Celia; Castilla-Ortega, María Estela; Razola-Díaz[et al.] (Royal Society of Chemistry, 2024-08-12)
Cocoa is widely known for its health benefits, but its neurocognitive impact remains underexplored. This preclinical study aimed to investigate the effects of cocoa and cocoa polyphenols on hippocampal neuroplasticity, ... -
Effects of cocoa-derived polyphenols treatment in regulating the adverse impacts of early-life stress in male and female mice.
Castro-Zavala, Adriana; Melgar-Locatelli, Sonia; Mañas-Padilla, María del Carmen; Rodríguez-Pérez, Celia; Castilla-Ortega, María Estela (2023)
Depression is one of the mental disorders that significantly affects today's society and calls for new treatments. In recent years, the gut microbiota has emerged as a key modulator of behaviour and mood due to the existence ... -
Evaluación neuropsicológica en daño cerebral adquirido: propuesta de aprendizaje basado en proyectos para estudiantes del máster en psicología general sanitaria.
Serrano-Ibáñez, Elena Rocío; Ortega-Acosta, Sergio; Mañas-Padilla, María del Carmen; Castro-Zavala, Adriana; Rodríguez-Martínez, María del Carmen; Castilla-Ortega, María Estela[et al.] (2023)
Se relata la experiencia docente del proyecto “Neuropsicoartes (Npsicoartes): mejorando la calidad de vida e integración social de las personas con daño cerebral adquirido”, financiado por la Universidad de Málaga en el ... -
Impact of a cocoa-based diet rich in polyphenols on cognitive function, emotional behavior, and adult hippocampal neurogenesis in mice.
Melgar-Locatelli, Sonia; Mañas-Padilla, María del Carmen; Castro-Zavala, Adriana; Razola-Díaz, María del Carmen; Palma-Morales, Marta; Rivera-González, Patricia; Rodríguez-Pérez, Celia; Castilla-Ortega, María Estela[et al.] (2023)
Cocoa consumption has long been associated with numerous health benefits due to its rich composition of minerals, fiber, methylxanthines, and polyphenols, particularly flavanols. However, the cognitive effects of cocoa ... -
Nutrition and adult neurogenesis in the hippocampus: Does what you eat help you remember?
(2023-02-23)Neurogenesis is a complex process by which neural progenitor cells (NPCs)/neural stem cells (NSCs) proliferate and differentiate into new neurons and other brain cells. In adulthood, the hippocampus is one of the areas ... -
Proyecto 'Neuropsicoartes’ (Npsicoartes): una experiencia interdisciplinar de aprendizaje basado en proyectos.
Serrano-Ibáñez, Elena Rocío; Ortega-Acosta, Sergio; Mañas-Padilla, María del Carmen; Castro-Zavala, Adriana; Rodríguez-Martínez, María del Carmen; Castilla-Ortega, María Estela[et al.] (2023)
Este capítulo de libro relata la experiencia docente del proyecto “Neuropsicoartes (Npsicoartes): mejorando la calidad de vida e integración social de las personas con daño cerebral adquirido”, financiado por la Universidad ... -
Sex-Specific Variations in Spatial Reference Memory Acquisition: Insights from a Comprehensive Behavioral Test Battery in C57BL/6JRj Mice.
Melgar-Locatelli, Sonia; Mañas-Padilla, María del Carmen; Gavito, Ana Luisa; Rivera, Patricia; Rodríguez-Pérez, Celia; Castilla-Ortega, María Estela; Castro-Zavala, Adriana[et al.] (2023)
Sex differences in declarative memory are described in humans, revealing a female or a male advantage depending on the task. Specifically, spatial memory (i.e., spatial navigation) is typically most efficient in men. This ...