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A service-learning educational approach developed the transversal competencies of undergraduate students in an outreach workshop aimed to high school students
In the last decade, research institutes and universities have strengthened the development of outreach activities in the biomedical field, involving researchers and professors as well as graduate students, but with little ... -
Antioxidant and neuroprotective actions of IGF-II against glucocorticoid-induced toxicity in dopaminergic neurons.
Claros-Gil, Silvia; Valverde Moreno, Nadia; Zamorano-González, Pablo; Romero-Zerbo, Silvana Yanina; Lara Fernández, Estrella; Boraldi, Federica; Pavía-Molina, José; García-Fernández, María Inmaculada; Gago-Calderón, Belén; Martín-Montañez, Elisa[et al.] (2023)The neurodegenerative Parkinson’s disease (PD) affects 1–3% of the population aged over 65. A wide range of pathways and mechanisms are involved in its pathogenesis, such as oxidative stress, mitochondrial dysfunction, ... -
Aplicación de rutinas y estrategias de aprendizaje en el ámbito universitario.
Martín-Ruiz, Isaías; Zamorano-González, Pablo; Barba-Quintero, María José; Wallace-Ruíz, Agustín (2023)La enseñanza universitaria está inmersa en un cambio continuo que viene marcado por la mejora de la calidad de enseñanza, y entre otras, por poner el énfasis en nuevas metodologías que tienen como protagonista al alumno, ... -
Cocaine detrimentally affects mitochondrial functionality and cell viability in dopaminergic neurons.
Zamorano-González, Pablo; Bandini, Luca; Valverde, Nadia; Claros-Gil, Silvia; Romero-Zerbo, Silvana Yanina; Lara, Estrella; Santín-Núñez, Luis Javier; Martín-Montañez, Elisa; Gago-Calderón, Belén; García-Fernández, María Inmaculada[et al.] (2024)An elevated consumption of cocaine (benzoylmethylecgonine), which causes anesthetic and stimulant effects on the central nervous system, may be associated with several neurodegenerative conditions affecting dopaminergic ... -
Galanin and neuropeptide Y interactions linked to neuronal precursor cells of the dentate gyrus in the hippocampus. Role in depression and cognitive impairment.
Fores-Pons, Ramón; Borroto Escuela, Dasiel Óscar; Pita-Rodríguez, Mariana; Barbancho-Fernández, Miguel Ángel; López-Salas, Alexander; Rosas-Marqués, Paloma; Zamorano-González, Pablo; Fuxe, Kjell; García-Casares, Natalia; Narváez-Peláez, Manuel[et al.] (2021-11-05)Galanin (GAL) interacts with Neuropeptide Y Y1 receptors (NPYY1R) in several regions of the central nervous system associated with mood and motivation, through GAL receptor 2 and NPYY1 receptor 1 (GALR2/NPYY1R) heterodimers. ... -
IGF-II treatment prevents the oxidative damage derived by MPP+/MPTP administration in a cellular and animal model of Parkinson’s disease.
Zamorano-González, Pablo; Valverde, Nadia; Claros-Gil, Silvia; López-González, Manuel Víctor; Romero-Zerbo, Silvana Yanina; Lara, Estrella; Boraldi, Federica; Pavía-Molina, José; García-Fernández, María Inmaculada; Gago-Calderón, Belén; Martín-Montañez, Elisa[et al.] (2023)El factor de crecimiento de la insulina-II (IGF-II) ha mostrado efectos antioxidantes y neuroprotectores en algunos trastornos neurodegenerativos, como es la Enfermedad de Parkinson (EP). Analizamos el efecto de IGF-II ... -
Intranasal Delivery of Galanin 2 and Neuropeptide Y1 Agonists Enhanced Spatial Memory Performance and antidepressant e!ects through Neuronal Precursor Cells Proliferation in the hippocampus
Borroto Escuela, Dasiel Óscar; Mirchandani-Duque, Marina; Fores-Pons, Ramón; Pita-Rodríguez, Mariana; Zamorano-González, Pablo; Barbancho-Fernández, Miguel Ángel; García-Casares, Natalia; Fuxe, Kjell; Narváez-Peláez, Manuel[et al.] (2022-07-07)Neuropeptide Y(NPY) Y1 receptor (Y1R) and galanin (GAL) receptor 2 (GALR2) interact in brain regions responsible for learning and memory processes, emphasizing the hippocampus. The current study assesses the sustained ... -
New molecular mechanisms to explain the neuroprotective effects of insulin-like growth factor II in a cellular model of Parkinson's disease
Romero-Zerbo, Silvana Yanina; Valverde, Nadia; Claros-Gil, Silvia; Zamorano-González, Pablo; Boraldi, Federica; Lofaro, Francesco-Demetrio; Lara, Estrella; Pavía-Molina, José; García-Fernández, María Inmaculada; Gago-Calderón, Belén; Martín-Montañez, Elisa[et al.] (Elsevier, 2024-02-08)Introduction One of the hallmarks of Parkinsońs Disease (PD) is oxidative distress, leading to mitochondrial dysfunction and neurodegeneration. Insulin-like growth factor II (IGF-II) has been proven to have antioxidant ... -
Service-learning educational approach for undergraduate students: development of an outreach workshop for high school students
Zamorano-González, Pablo; Aiastui Pujana, Ana; García-Durán, Laura; Claros-Gil, Silvia; López-González, Manuel Víctor; González-García, Marta; Carrillo-Franco, Laura; Ponce-Velasco, Marina; Gago-Calderón, Belén[et al.] (2023)In the last decade, research institutes and universities have strengthened the development of outreach activities in the biomedical field, involving researchers and professors as well as graduate students, but with little ... -
Teaching the physiology of the human body in non-formal spaces: pilot experience of a Service-Learning methodology and the interaction between students of different educational levels
García-Durán, Laura; Claros-Gil, Silvia; Zamorano-González, Pablo; González-García, Marta; Carrillo-Franco, Laura; Ponce-Velasco, Marina; Gago-Calderón, Belén; García-Fernández, María Inmaculada; López-González, Manuel Víctor; Aiastui Pujana, Ana[et al.] (Frontiers Media, 2023)Research institutes and universities have strengthened the development of biomedicine outreach activities, constituing a non-formal education system of science literacy, although with little commitment from undergraduate ...