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Listar por autor "García-Bonilla, María"
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Bone marrow-derived mesenchymal stem cells characterization and transplantation in an animal model of congenital hydrocephalus
García-Bonilla, María; Cifuentes-Rueda, Manuel; Ho-Plagaro, Ailec; Santos-Ruiz, Leonor
; Shumilov, Kirill; Pérez-Fígares, José Manuel; Jimenez-Lara, Antonio Jesus
[et al.] (2015-10-08)
Congenital hydrocephalus is a disorder presenting a degeneration of the periventricular cerebral parenchyma and the white matter, which causes significant mortality and life-long neurological complications. There are ... -
Bone marrow-derived mesenchymal stem cells transplantation produces a tissue recovery in hydrocephalic mice
García-Bonilla, María; Shumilov, Kirill; Vitorica, Javier; García-Martín, María Luisa; Muñoz, Carmen; Claros-Gil, Silvia; Gutierrez-Perez, Antonia
; Jimenez-Lara, Antonio Jesus
[et al.] (2018-07-25)
In congenital hydrocephalus, cerebrospinal fluid accumulation is associated to ischemia/hypoxia, metabolic impairment, neuronal damage and astrocytic reaction, which cause significant mortality and life-long neurological ... -
Characterization and administration of bone marrow-derived mesenchymal stem cells in an animal model of congenital hydrocephalus
García-Bonilla, María; Cifuentes-Rueda, Manuel; Ho-Plagaro, Ailec; Shumilov, Kirill; Santos-Ruiz, Leonor
; Pérez-Fígares, José Manuel; Jimenez-Lara, Antonio Jesus
[et al.] (2015-07-08)
Bone marrow-derived mesenchymal stem cells (BM-MSC) are considered as a potential therapeutic tool in neurodegenerative diseases, due to their ability to migrate to degenerated tissues and the production of growth factors. ... -
Effect of bone marrow-derived mesenchymal stem cells on congenital hydrocephalus in the hyh mouse
García-Bonilla, María; Shumilov, Kirill; Vitorica, Javier; García-Martín, María Luisa; Muñoz, Carmen; Jimenez, Sebastian; Navarro, Victoria; García-Cuervo, Luisa; Cifuentes-Rueda, Manuel; Claros-Gil, Silvia
; Andrades-Gomez, Jose Antonio
; Guitérrez, Antonia; Paez-Gonzalez, Patricia
; Jimenez-Lara, Antonio Jesus
[et al.] (2017-06-28)
Background Bone marrow-derived mesenchymal stem cells (BM-MSC) are considered as a potential therapeutic tool for neurodegenerative diseases due to their ability for migrating into damaged tissue. Additionally, these cells ... -
Long-time effects of an experimental therapy with mesenchymal stem cells in congenital hydrocephalus
García-Bonilla, María; Ojeda-Pérez, Betsaida; Shumilov, Kirill; Vitorica, Javier; Guitérrez, Antonia; Paez-Gonzalez, Patricia; Jimenez-Lara, Antonio Jesus
[et al.] (2019-07-03)
Introduction: Bone marrow-derived mesenchymal stem cells (BM-MSC) are a potential therapeutic tool due to their ability for migrating and producing neuroprotector factors when they are transplanted in other neurodegenerative ... -
A metabolite profile reveals the presence of neurodegenerative conditions according to severity of hydrocephalus
García-Bonilla, María; Shumilov, Kirill; García-Martín, María Luisa; Muñoz, María Carmen; Domínguez-Pinos, Dolores; Gutierrez-Perez, Antonia
; Paez-Gonzalez, Patricia
; Jimenez-Lara, Antonio Jesus
[et al.] (2018-11-29)
Introduction: In obstructive congenital hydrocephalus, cerebrospinal fluid accumulation is associated with high intracranial pressure (ICP), ischemia/hypoxia, metabolic impairment, neuronal damage and astrocytic reaction. ... -
NG2 cells in an animal model of congenital hydrocephalus
Jimenez-Lara, Antonio Jesus; Ojeda-Pérez, Betsaida; García-Bonilla, María; Ruz-Maldonado, Inmaculada; Mateos-Grondona, Jesús
; Rodriguez-Perez, Luis Manuel
; Paez-Gonzalez, Patricia
[et al.] (2017-06-28)
NG2 cells are considered oligodendrocyte precursor cells (OPC). In pathological conditions, NG2 cells contribute to generate oligodendrocytes and reactive astrocytes. This study has been designed to uncover the role of NG2 ... -
Orientación y mejora de competencias de comunicación a través del análisis crítico entre estudiantes de Trabajo Fin de Grado
Arrojo-Agudo, Maria Angeles; Pascual, Mª Belén; Flores-Burgess, Antonio
; De-la-Torre-Fazio, Fernando Nicolas
; García-Bonilla, María; Jimenez-Lara, Antonio Jesus
; Moreno-Ostos, Enrique
; Sesmero-Carrasco, Rafael Enrique
[et al.] (2019-07-05)
El Trabajo Fin de Grado (TFG), asignatura obligatoria que el estudiante debe realizar autónoma e individualmente, es un trabajo original que será presentado y defendido ante un Tribunal de Evaluación. Su implantación ha ... -
Potential protective role of reactive astrocytes in the periventricular parenchyma in congenital hydrocephalus
García-Bonilla, María; Shumilov, Kirill; Peñalver, Ana; Castilla, Laura; Alonso-Carrión, Francisco José; Márquez-Gómez, Javier
; García-Martín, María Luisa; Muñoz, Carmen; Gutierrez-Perez, Antonia
; Jimenez-Lara, Antonio Jesus
[et al.] (2016-07-11)
Background Cerebrospinal fluid accumulation in hydrocephalus produces an elevation of intraventricular pressure with pathological consequences on the periventricular brain parenchyma including ischemia, oedema, oxidative ...