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Listar por autor "Jimenez-Lara, Antonio Jesus"
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Aplicación de estrategias de aprendizaje para la adquisición de competencias profesionales y su evaluación mediante una rúbrica integradora en diversos títulos de grado de la Universidad de Málaga
Santacruz-Cruz, Maria Isabel; Díaz-Ramos, Antonio; López-Guerrero, María del Mar; Aranda-Garrido, Maria Lourdes; Martín-Valero, Rocío; [et al.] (2015-07-28)El Espacio Europeo de Educación Superior ha supuesto importantes cambios en el proceso de enseñanza-aprendizaje para la adquisición de competencias transversales y específicas. La calidad es un factor estratégico, por lo ... -
Aplicación de una terapia celular basada en células madre mesenquimales en un modelo animal de hidrocefalia congénita
Garcia Bonilla, Maria (UMA Editorial, 2020-01-08)La hidrocefalia congénita es una condición patológica caracterizada por la acumulación de líquido cefalorraquídeo, con unas manifestaciones fisiopatológicas que incluyen: dilatación de los ventrículos cerebrales ... -
Bone marrow-derived mesenchymal stem cells characterization and transplantation in an animal model of congenital hydrocephalus
García-Bonilla, María; Cifuentes, Manuel; Ho-Plagaro, Ailec; Santos-Ruiz, Leonor; Shumilov, Kirill; [et al.] (2015-10-08)Congenital hydrocephalus is a disorder presenting a degeneration of the periventricular cerebral parenchyma and the white matter, which causes significant mortality and life-long neurological complications. There are ... -
Bone marrow-derived mesenchymal stem cells transplantation produces a tissue recovery in hydrocephalic mice
García-Bonilla, María; Shumilov, Kirill; Vitorica, Javier; García-Martín, María-Luisa; Muñoz, Carmen; [et al.] (2018-07-25)In congenital hydrocephalus, cerebrospinal fluid accumulation is associated to ischemia/hypoxia, metabolic impairment, neuronal damage and astrocytic reaction, which cause significant mortality and life-long neurological ... -
Brain tissue recovery in obstructive congenital hydrocephalus after intraventricular transplantation of mesenchymal stem cells
García-Bonilla, María; Ojeda-Pérez, B.; Shumilov, Kirill; Vitorica, J.; García-Martín, María-Luisa; [et al.] (2018-10-29)Introduction: Bone marrow-derived mesenchymal stem cells (BM-MSC) are a potential therapeutic tool due to their ability for migrating and producing neuroprotector factors when transplanted. The aim of this study was to ... -
Characterization and administration of bone marrow-derived mesenchymal stem cells in an animal model of congenital hydrocephalus
García-Bonilla, María; Cifuentes, Manuel; Ho-Plagaro, Ailec; Shumilov, Kirill; Santos-Ruiz, Leonor; [et al.] (2015-07-08)Bone marrow-derived mesenchymal stem cells (BM-MSC) are considered as a potential therapeutic tool in neurodegenerative diseases, due to their ability to migrate to degenerated tissues and the production of growth factors. ... -
Desarrollo del epéndimo y subepéndimo en modelos animales en condiciones normales y en la hidrocefalia congénita
Rodriguez-Perez, Luis Manuel (Servicio de Publicaciones y Divulgacion Cientifica, 2016)La presente Tesis Doctoral se ha diseñado para responder a las siguientes hipótesis: 1.- El programa de diferenciación de la zona ventricular que se afecta en el ratón hyh pone de manifiesto que la población celular que ... -
Effect of bone marrow-derived mesenchymal stem cells on congenital hydrocephalus in the hyh mouse
García-Bonilla, María; Shumilov, Kirill; Vitorica, Javier; García-Martín, María Luisa; Muñoz, Carmen; [et al.] (2017-06-28)Background Bone marrow-derived mesenchymal stem cells (BM-MSC) are considered as a potential therapeutic tool for neurodegenerative diseases due to their ability for migrating into damaged tissue. Additionally, these cells ... -
IPSC differentiation into ependymal progenitors to treat ventricular damage during hydrocephalus
Rodríguez-Pérez, Luis Manuel; Jimenez-Lara, Antonio Jesus; Páez-González, Patricia (2018-10-30)Introduction: During both obstructive congenital hydrocephalus and post-hemorrhagic hydrocephalus additional pathological events are intimately associated with their ethiology: a) a detrimental inflammatory response; b) ... -
iPSC differentiation into ependymal progenitors to treat ventricular damage during hydrocephalus
Rodríguez-Pérez, Luis Manuel; Hidalgo-Díaz, Juan Antonio; Jimenez-Lara, Antonio Jesus; Páez-González, Patricia (2019-07-03)Introduction: During both obstructive congenital hydrocephalus and post-hemorrhagic hydrocephalus additional pathological events are intimately associated with their ethiology: a) a detrimental inflammatory response; b) ... -
Learning strategies for the acquisition of specific skills, and its evaluation through an integrated rubric in several degrees of University of Malaga (Spain).
Santacruz-Cruz, Maria Isabel; Díaz-Ramos, Antonio; López-Guerrero, María del Mar; Aranda-Garrido, Maria Lourdes; Martín-Valero, Rocío; [et al.] (2015-07-28)It is essential for the university lecturers/professors to design new strategies that help students to acquire skills in the new framework of the European Higher Education Area. Furthermore, the assessment of the effectiveness ... -
Long-time effects of an experimental therapy with mesenchymal stem cells in congenital hydrocephalus
García-Bonilla, María; Ojeda, Betsaida; Shumilov, Kirill; Vitorica, Javier; Guitérrez, Antonia; [et al.] (2019-07-03)Introduction: Bone marrow-derived mesenchymal stem cells (BM-MSC) are a potential therapeutic tool due to their ability for migrating and producing neuroprotector factors when they are transplanted in other neurodegenerative ... -
Metabolite fingerprint detected with HR-MAS spectroscopy in ex vivo samples of cases with congenital hydrocephalus
Jimenez-Lara, Antonio Jesus; García-Martín, María Luisa; Muñoz, Carmen; Domínguez-Pinos, María Dolores,; Martínez-León, María Isabel; [et al.] (2014-07-16)Background: Changes in the profile of metabolites in brain and/or fluids can be useful to evaluate the severity and evolution of hydrocephalus, and consequently to help in treatment decisions. Magnetic Resonance Spectroscopy ... -
A metabolite profile reveals the presence of neurodegenerative conditions according to severity of hydrocephalus
García-Bonilla, María; Shumilov, Kirill; García-Martín, María Luisa; Muñoz, María Carmen; Domínguez-Pinos, Dolores; [et al.] (2018-11-29)Introduction: In obstructive congenital hydrocephalus, cerebrospinal fluid accumulation is associated with high intracranial pressure (ICP), ischemia/hypoxia, metabolic impairment, neuronal damage and astrocytic reaction. ... -
Neuropathological events in an animal model resembling human fetal post-hemorrhagic hydrocephalus
Ojeda-Pérez, Betsaida; Páez-González, Patricia; Jimenez-Lara, Antonio Jesus (2019-07-03)Introduction: In premature newborns, intraventricular hemorrhages (IVH) probably trigger the disruption of the neurogenic ventricular zone. Most of the cases with severe IVH develop post-hemorrhagic hydrocephalus (PHH). ... -
NG2 cells in an animal model of congenital hydrocephalus
Jimenez-Lara, Antonio Jesus; Ojeda, Betsaida; García-Bonilla, María; Ruz-Maldonado, Inmaculada; Grondona, Jesús M; [et al.] (2017-06-28)NG2 cells are considered oligodendrocyte precursor cells (OPC). In pathological conditions, NG2 cells contribute to generate oligodendrocytes and reactive astrocytes. This study has been designed to uncover the role of NG2 ... -
Orientación y mejora de competencias de comunicación a través del análisis crítico entre estudiantes de Trabajo Fin de Grado
Arrojo Agudo, M. Ángeles; Pascual, Mª Belén; Flores-Burgess, Antonio; de la Torre, Fernando; García-Bonilla, María; [et al.] (2019-07-05)El Trabajo Fin de Grado (TFG), asignatura obligatoria que el estudiante debe realizar autónoma e individualmente, es un trabajo original que será presentado y defendido ante un Tribunal de Evaluación. Su implantación ha ... -
Potential protective role of reactive astrocytes in the periventricular parenchyma in congenital hydrocephalus
García-Bonilla, María; Shumilov, Kirill; Peñalver, Ana; Castilla, Laura; Alonso-Carrion, Francisco Jose; [et al.] (2016-07-11)Background Cerebrospinal fluid accumulation in hydrocephalus produces an elevation of intraventricular pressure with pathological consequences on the periventricular brain parenchyma including ischemia, oedema, oxidative ... -
Procesos Neuropatológicos Comunes Asociados a las Paredes Ventriculares en la Hidrocefalia Congénita Humana
Domínguez Pinos, Dolores (Servicio de Publicaciones y Divulgación Científica, 2016)La hidrocefalia se define hoy en como una distensión activa del sistema ventricular debida a una acumulación neta de líquido cefalorraquídeo (LCR). Puede deberse a varias razones, donde se pueden encontrar obstrucciones ...