Listar por autor "Larrosa-Jiménez, Rafael"
Mostrando ítems 1-7 de 7
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Advancements in long-read genome sequencing technologies and algorithms
Espinosa García, Elena María; Bautista-Moreno, Rocío
; Larrosa-Jiménez, Rafael; Plata-González, Óscar Guillermo (Elsevier, 2024-03)
The recent advent of long read sequencing technologies, such as Pacific Biosciences (PacBio) and Oxford Nanopore technology (ONT), have led to substantial improvements in accuracy and computational cost in sequencing ... -
Biomarker potential of repetitive-element transcriptome in lung cancer
Claros-Díaz, Manuel Gonzalo; Arroyo, Macarena; Bautista-Moreno, Rocío; Larrosa-Jiménez, Rafael; Cobo, Manuel Ángel (PeerJ, 2019)
Since repetitive elements (REs) account for nearly 53% of the human genome, profiling its transcription after an oncogenic change might help in the search for new biomarkers. Lung cancer was selected as target since it is ... -
Comparing assembly strategies for third-generation sequencing technologies across different genomes
Espinosa García, Elena María; Bautista-Moreno, Rocío; Fernández, Iván; Larrosa-Jiménez, Rafael; López-Zapata, Emilio; Plata-González, Óscar Guillermo[et al.] (Elsevier, 2023-09)
The recent advent of long-read sequencing technologies, such as Pacific Biosciences (PacBio) and Oxford Nanopore technology (ONT), has led to substantial accuracy and computational cost improvements. However, de novo ... -
Construction of miRNA–mRNA networks for the identification of lung cancer biomarkers in liquid biopsies
Espinosa García, Elena María; Arroyo Varela, Macarena; Larrosa-Jiménez, Rafael; Gómez‑Maldonado, Josefa; Cobo Dols, Manuel Ángel; Claros-Díaz, Manuel Gonzalo; Bautista-Moreno, Rocío[et al.] (Springer Nature, 2022-10-12)
Lung cancer (LC) is the most common cause of cancer death worldwide mostly due to the low survival rate: 75% of cases are identified in advanced stages. In this study, the list of useful biomarkers to make an early diagnosis ... -
miRNA as biomarker in lung cancer
Salcedo Lobera, Esperanza; Arroyo Varela, Macarena; Larrosa-Jiménez, Rafael; Bautista-Moreno, Rocío (Springer Nature, 2023-08-29)
Lung cancer has a high prevalence and mortality due to its late diagnosis and limited treatment, so it is essential to find biomarkers that allow a faster diagnosis and improve the survival of these patients. In this sense, ... -
Optimización de la Entrada Salida mediante librerías y lenguajes paralelos
Larrosa-Jiménez, Rafael (Servicio de Publicaciones y Divulgación Científica, 2016)
Uno de los grandes retos de la HPC (High Performance Computing) consiste en optimizar el subsistema de Entrada/Salida, (E/S), o I/O (Input/Output). Ken Batcher resume este hecho en la siguiente frase: "Un supercomputador ... -
Whole-Genome Assembly: An Experimental Study of Computational Costs and Architectural Opportunities
Espinosa García, Elena María; López-Fernández, Iván; Larrosa-Jiménez, Rafael; Plata-González, Óscar Guillermo (2022)
Whole-genome sequencing (WGS) pro- vides a huge amount of reads from which a comple- te genome could be assembled. The recent advent of long read sequencing technologies, such as PacBio and Oxford Nanopore, and the subsequent ...