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Listar por autor "Cárdenas García, Casimiro"
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Antiangiogenic potential of an olive oil extract: insights from a proteomic study
Marrero Capitán, Ana Dácil; Cárdenas García, Casimiro; Castilla, Laura; Ortega Vidal, Juan; Rodríguez-Quesada, Ana María; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel[et al.] (ACS, 2024)Extra virgin olive oil (EVOO), a staple of the Mediterranean diet, is rich in phenolic compounds recognized for their potent bioactive effects, including anticancer and anti-inflammatory properties. However, its effects ... -
Antioxidant, Immunomodulatory and Potential Anticancer Capacity of Polysaccharides (Glucans) from Euglena gracilis G.A. Klebs
Casas Arrojo, Virginia; Arrojo-Agudo, María Ángeles; Cárdenas García, Casimiro; Carrillo Fernández, Paloma; Pérez Manríquez, Claudia; Martínez-Manzanares, Eduardo; Abdala-Díaz, Roberto Teófilo[et al.] (IOAP-MDPI, 2022-11-10)The present study was carried out to determine the bioactivity of polysaccharides extracted from Euglena gracilis (EgPs). These were characterized by FT-IR and GC-MS. Cytotoxicity analyses (MTT) were performed on healthy ... -
Generation of periventricular reactive astrocytes overexpressing aquaporin 4 Is stimulated by mesenchymal stem cell therapy
García-Bonilla, María; Ojeda-Pérez, Betsaida; Shumilov, Kirill; Rodríguez-Pérez, Luis Manuel; Domínguez-Pinos, Dolores; Vitorica Ferrández, Javier; Jiménez, Sebastián; Ramírez-Lorca, Reposo; Echevarría, Miriam; Cárdenas García, Casimiro; Iglesias, Teresa; Gutiérrez-Pérez, Antonia; McAllister, James P. (II); Limbrick, David D. (Jr.); Páez-González, Patricia; Jiménez-Lara, Antonio Jesús[et al.] (MDPI, 2023-03-15)Aquaporin-4 (AQP4) plays a crucial role in brain water circulation and is considered a therapeutic target in hydrocephalus. Congenital hydrocephalus is associated with a reaction of astrocytes in the periventricular white ... -
Homocysteine treatment alters redox capacity of both endothelial and tumor cells
Díaz-Santiago, Elena Dolores; Rodríguez Caso, Luis; Cárdenas García, Casimiro; Serrano, José J.; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel[et al.] (2015-10-22)Homocysteine is a non-proteinogenic amino acid playing key roles in two interconnected metabolic pathways, namely, the activated methyl cycle and the linear trans-sulfuration pathway that allows the conversion of methionine ... -
Identification of key molecular biomarkers involved in reactive and neurodegenerative processes present in inherited congenital hydrocephalus
Ojeda-Pérez, Betsaida; Campos-Sandoval, José Ángel; García-Bonilla, María; Cárdenas García, Casimiro; Páez-González, Patricia; Jiménez-Lara, Antonio Jesús[et al.] (BMC, 2021)Periventricular extracellular oedema, myelin damage, inflammation, and glial reactions are common neuropathological events that occur in the brain in congenital hydrocephalus. The periventricular white matter is the most ... -
Immunomodulatory and antioxidant activity of acidic polysaccharides from laminaria ochroleuca, porphyra umbilicalis and gelidium corneum
Casas Arrojo, Virginia; Arrojo-Agudo, María Ángeles; Cárdenas García, Casimiro; Drobetsov, Sergay; López-Figueroa, Félix; Abdala-Díaz, Roberto Teófilo[et al.] (2018-10-17)Las algas marinas del género Laminaria, Gelidium y Porphyra se han utilizado en industrias alimentarias y no alimentarias debido a sus propiedades y su actividad biológica. Los polisacáridos sulfatados de algas ofrecen ... -
Non-targeted metabolomics characterization of Annona muricata leaf extracts with anti-angiogenic activity
Cárdenas García, Casimiro; Torres-Vargas, José Antonio; Cárdenas Valdivia, Abel; Jurado, Nuria; Rodríguez-Quesada, Ana María; García-Caballero, Melissa; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel[et al.] (ELSEVIER, 2021-11)The tropical plant Annona muricata has been widely used for traditional ethnobotanic and pharmacologic applications. Extracts from different parts of this plant have been shown to have a wide range of biological activities. ... -
Secretory Profile of Adipose-Tissue-Derived Mesenchymal Stem Cells from Cats with Calicivirus-Positive Severe Chronic Gingivostomatitis
Villatoro, Antonio J.; Martín Astorga, María del Carmen; Alcoholado Cueto, Cristina; Kazantseva, Liliya; Cárdenas García, Casimiro; Fariñas Guerrero, Fernando; Becerra-Ratia, José; Visser, Rick[et al.] (IOAP-MPDI, 2022-05-25)The feline calicivirus (FCV) causes infections in cats all over the world and seems to be related to a broad variety of clinical presentations, such as feline chronic gingivostomatitis (FCGS), a severe oral pathology in ... -
Study of Bioactive Compounds Extracted From Natural Products with Effects on Angiogenesis, Inflammation and Tumor Development
Cárdenas García, Casimiro (Universidad de Málaga, Servicio de Publicaciones y Divulgación Científica, 2014)Durante el curso de esta tesis se han generado cuatro artículos de investigación y un capítulo de libro. A continuación se muestra un resumen de sus resultados y conclusiones. En el primer trabajo de investigación, ... -
The coffee diterpene kahweol is an antitumoral compound for human estrogen receptor-negative breast cancer cells
Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María; Cárdenas García, Casimiro (SEBBM, 2013-09-04)Although epidemiological studies indicate that coffee consumption is associated with a low incidence of several kinds of cancer, there are still few studies on the anti-tumoral effects of pure bioactive compounds isolated ...