Listar por autor "Sánchez-Mejías, Elisabeth"
Mostrando ítems 1-4 de 4
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Astroglial reactivity in response to b-amyloidosis is associated with mithocondrial pathology in the hippocampus of Alzheimer's transgenic mice
López Oliva, Elba; Trujillo-Estrada, Laura Isabel
; Sanchez Mejias, Elisabeth; Mejias-Ortega, Marina; Fernández-Valenzuela, Juan José; Gomez-Arboledas, Angela; Dávila-Cansino, José Carlos; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia[et al.] (2023-04)
Aims: Alzheimer’s diseaase (A)D is associated with early energy hypometabolism, synaptic and mitochondrial dysfunction, oxidative stress, inflammation, abnormal proteostasis and progressive neurodegeneration. During the ... -
Estudio neuropatológico del hipocampo y giro parahipocampal en la enfermedad de Alzheimer: de modelos transgénicos a humanos
(Servicio de Publicaciones y Divulgación Científica, 2015)La actual ausencia de tratamientos efectivos para la enfermedad de Alzheimer (AD) pone de manifiesto la necesidad urgente de caracterizar la evolución de la patología en muestras de pacientes para así entender mejor los ... -
Peripheral myeloid cells infiltrate the hippocampus of Alzheimer's disease patients.
Mejías-Ortega, Marina; Muñoz-Castro, Clara; Sánchez-Mejías, Elisabeth; Jimenez, Sebastian; Trujillo-Estrada, Laura Isabel; Vizuete, María Luisa; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia[et al.] (2023)
Microglia, the brain-resident myeloid cells, play a major role in the immune responses of the nervous system and in the pathogenesis of Alzheimer's disease (AD). However, the presence of peripheral myeloid cells in the AD ... -
Transgenic Mouse Models of Alzheimer’s Disease: An Integrative Analysis
Sánchez-Varo, Raquel María; Mejías-Ortega, Marina; Fernández-Valenzuela, Juan José; Núñez Díaz, Cristina; Cáceres Palomo, Laura; Vegas-Gómez, Laura; Sánchez Mejías, Elisabeth; Trujillo-Estrada, Laura Isabel; Moreno González, Inés; García-León, Juan Antonio; Vizuete, María Luisa; Vitorica Ferrández, Javier; Baglietto-Vargas, David; Gutiérrez-Pérez, Antonia[et al.] (IOAP-MPDI, 2022-05-12)
Alzheimer’s disease (AD) constitutes the most prominent form of dementia among elderly individuals worldwide. Disease modeling using murine transgenic mice was first initiated thanks to the discovery of heritable mutations ...