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Protein tyrosine phosphatase gene (PTPN22) polymorphism in multiple sclerosis.
Matesanz, Fuencisla; Rueda, Blanca; Orozco, Gisela; Fernández-Fernández, Óscar; Leyva-Fernández, Laura; Alcina, Antonio; Martín-Ibáñez, Javier[et al.] (Springer, 2005-03-17)Alterations in the signalling pathway that regulate T-cell tyrosine phosphorylation play an important role in MS. Tyrosine phosphorylation is regulated by the equal and balanced action of protein tyrosine kinases and protein ...