Listar por autor "Garcia-Fernàndez, Jordi"
Mostrando ítems 1-6 de 6
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Evolution of Hox gene clusters in deuterostomes
(BMC, 2013-07-02)Hox genes, with their similar roles in animals as evolutionarily distant as humans and flies, have fascinated biologists since their discovery nearly 30 years ago. During the last two decades, reports on Hox genes from a ... -
Gene expansion and retention leads to a diverse tyrosine kinase superfamily in amphioxus
(Oxford University Press, 2008)Tyrosine kinase (TK) proteins play a central role in cellular behavior and development of animals. The expansion of this superfamily is regarded as a key event in the evolution of the complex signaling pathways and gene ... -
Implications of duplicated cis-regulatory elements in the evolution of metazoans: the DDI model or how simplicity begets novelty.
(Oxford Academic, 2009)The discovery that most regulatory genes were conserved among animals from distant phyla challenged the ideas that gene duplication and divergence of homologous coding sequences were the basis for major morphological changes ... -
The Amphioxus Hox Cluster: Characterization, Comparative Genomics, and Evolution.
(Wiley, 2008-03-19)The amphioxus Hox cluster is often viewed as ‘‘archetypal’’ for the chordate lineage. Here, we present a descriptive account of the 448 kb region spanning the Hox cluster of the amphioxus Branchiostoma floridae from Hox14 ... -
The evolutionary origins of chordate hematopoiesis and vertebrate endothelia
Pascual-Anaya, Juan; Albuixech-Crespo, Beatriz; Somorjai, Ildikó M. L.; Carmona-Mejías, Rita María
; Oisi, Yasuhiro; Álvarez, Susana; Kuratani, Shigeru; Muñoz-Chápuli-Oriol, Ramón; Garcia-Fernàndez, Jordi[et al.] (Elsevier, 2013-03-15)
The vertebrate circulatory system is the most complex vascular system among those of metazoans, with key innovations including a multi-chambered heart and highly specialized blood cells. Invertebrate vessels, on the other ... -
Unexpectedly large number of conserved noncoding regions within the ancestral chordate Hox cluster
(Springer, 2008)The single amphioxus Hox cluster contains 15 genes and may well resemble the ancestral chordate Hox cluster. We have sequenced the Hox genomic complement of the European amphioxus Branchiostoma lanceolatum and compared it ...