Listar por autor "Sánchez-Salido, Lourdes"
Mostrando ítems 1-9 de 9
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Abnormal cannabidiol ameliorates inflammation preserving pancreatic beta cells in mouse models of experimental type 1 diabetes and beta cell damage
González-Mariscal, Isabel; Pozo-Morales, Macarena; Romero-Zerbo, Silvana Yanina
; Espinosa-Jiménez, Vanesa; Escamilla-Sánchez, Alejandro; Sánchez-Salido, Lourdes; Cobo-Vuilleumier, Nadia; Gauthier, Benoit R.; Bermúdez Silva, Francisco Javier[et al.] (Elsevier, 2021-12-03)
The atypical cannabinoid Abn-CBD improves the inflammatory status in preclinical models of several pathologies, including autoimmune diseases. However, its potential for modulating inflammation in autoimmune type 1 diabetes ... -
Alpha-tocopherol protects against oxidative stress in the fragile X knockout mouse: an experimental therapeutic approach for the Fmr1 deficiency.
De Diego‑Otero, Yolanda; Romero-Zerbo, Silvana Yanina; El-Bekay, Rajaa; Decara, Juan; Sánchez-Salido, Lourdes; Rodriguez-de-Fonseca, Fernando; Del Arco-Herrera, Ignacio[et al.] (Springer Nature, 2009)
Fragile X syndrome is the most common genetic cause of mental disability. The mechanisms underlying the pathogenesis remain unclear and specific treatments are still under development. Previous studies have proposed an ... -
Enhanced markers of oxidative stress, altered antioxidants and NADPH-oxidase activation in brains from Fragile X mental retardation 1-deficient mice, a pathological model for Fragile X syndrome.
El-Bekay, Rajaa; Romero-Zerbo, Silvana Yanina; Decara, Juan; Sánchez-Salido, Lourdes; Del Arco-Herrera, Ignacio; Rodriguez-de-Fonseca, Fernando; De Diego‑Otero, Yolanda[et al.] (Wiley, 2007)
Fragile X syndrome is the most common form of inherited mental retardation in humans. It originates from the loss of expression ofthe Fragile X mental retardation 1 (FMR1) gene, which results in the absence of the Fragile ... -
Environmental enrichment alleviates cognitive and psychomotor alterations and increases adult hippocampal neurogenesis in cocaine withdrawn mice
Mañas-Padilla, María del Carmen; Tezanos, Patricia; Cintado, Elisa; Vicente, Lucía; Sánchez-Salido, Lourdes; Gil-Rodríguez, Sara; Trejo-Pérez, José Luis; Santín-Núñez, Luis Javier; Castilla-Ortega, María Estela[et al.] (Wiley, 2022-11-16)
Cocaine is a widely used psychostimulant drug whose repeated exposure induces persistent cognitive/emotional dysregulation, which could be a predictor of relapse in users. However, there is scarce evidence on effective ... -
GABAergic deficits in absence of LPA1 receptor, associated anxiety-like and coping behaviors, and amelioration by interneuron precursor transplants into the dorsal hippocampus
Rosell-Valle, Cristina; Martínez-Losa, Magdalena; Matas-Rico, Elisa; Castilla-Ortega, María Estela; Zambrana-Infantes, Emma; Gómez-Conde, Ana Isabel; Sánchez-Salido, Lourdes; Ladrón de Guevara-Miranda, David; Pedraza-Benítez, María del Carmen; Serrano-Castro, Pedro Jesús; Chun, Jerold; Rodríguez de Fonseca, Fernando; Álvarez Dolado, Manuel; Santín-Núñez, Luis Javier; Estivill-Torrús, Guillermo[et al.] (Springer Link, 2021-04-01)
Defects in GABAergic function can cause anxiety- and depression-like behaviors among other neuropsychiatric disorders. Therapeutic strategies using the transplantation of GABAergic interneuron progenitors derived from the ... -
Pigment epithelium-derived factor (PEDF) and PEDF-receptor in the adult mouse brain: Differential spatial/temporal localization pattern
De-Diego-Otero, María Yolanda; Giráldez-Pérez, Rosa María; Lima-Cabello, Elena; Heredia-Farfán, Raúl; Calvo Medina, Rocío; Sánchez-Salido, Lourdes; Pérez-Costillas, Lucía María[et al.] (2020-05-19)
Pigment epithelium-derived factor (PEDF) is a multifunctional protein which was initially described in the retina, although it is also present in other tissues. It functions as an antioxidant agent promoting neuronal ... -
Protective effects of melatonin against oxidative stress in Fmr1 knockout mice: a therapeutic research model for the fragile X syndrome
Romero-Zerbo, Silvana Yanina; Decara, Juan; El Bekay Rizky, Rajaa; Sánchez-Salido, Lourdes; Del Arco-Herrera, Ignacio; Rodriguez-de-Fonseca, Fernando; De-Diego-Otero, María Yolanda[et al.] (Blackwell Munksgaard, 2009)
Fragile X syndrome is the most common form of inherited mentalretardation. It is typically caused by a mutation of the Fragile X mental-retardation 1 (Fmr1) gene. To better understand the role of the Fmr1 geneand its gene ... -
The Atypical Cannabinoid Abn-CBD Reduces Inflammation and Protects Liver, Pancreas, and Adipose Tissue in a Mouse Model of Prediabetes and Non-alcoholic Fatty Liver Disease
Romero-Zerbo, Silvana Yanina; García-Fernández, María Inmaculada; Espinosa-Jiménez, Vanesa; Pozo-Morales, Macarena; Escamilla-Sánchez, Alejandro; Sánchez-Salido, Lourdes; Lara, Estrella; Cobo-Vuilleumier, Nadia; Rafacho, Alex; Olveira-Fuster, Gabriel María; Rojo-Martínez, Gemma; Gauthier, Benoit R.; González-Mariscal, Isabel; Bermúdez Silva, Francisco Javier[et al.] (Frontiers, 2020-03-06)
Background and Aims: The synthetic atypical cannabinoid Abn-CBD, a cannabidiol (CBD) derivative, has been recently shown to modulate the immune system in different organs, but its impact in obesity-related meta-inflammation ...