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Listar por autor "Rosales, Tracy"
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Metabolic changes upon GLS inhibition by CB-839 in glioma cell lines
Santos jiménez, Juan de los; Rosales, Tracy; Ko, Bookyung; Márquez-Gómez, Javier; Berardinis, Ralph J. de; [et al.] (2012-07-19)Many tumors use Gln for both energy generation and as a biosynthetic precursor. Glutaminases (GAs) catalyze the first step of glutaminolysis by converting glutamine (Gln) into glutamate and ammonia in the mitochondria. In ... -
Metabolic impact of glutaminase isoenzymes modulation on glioma cell lines
de los Santos-Jiménez, Juan; Rosales, Tracy; Bookyung, Ko; Márquez-Gómez, Javier; DeBerardinis, Ralph J; [et al.] (2022)Many tumors use glutamine for both energy generation and as a biosynthetic precursor. Glutaminases (GAs) catalyze the first step of glutaminolysis by converting glutamine (Gln) into glutamate and ammonia in the mitochondria. ...