- RIUMA Principal
- Listar por autor
Listar por autor "Carmeliet, Peter"
Mostrando ítems 1-4 de 4
-
Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesis.
Meçe, Odeta; Houbaert, Diede; Sassano, Maria-Livia; Durré, Tania; Maes, Hannelore; Schaaf, Marco; More, Sanket; Ganne, Maarten; García-Caballero, Melissa; Born, Mila; Verhoeven, Jelle; Agrawal, Madhur; Jacobs, Kathryn; Bergers, Gabriele; Blacher, Silvia; Ghesquière, Bart; Dewerchin, Mieke; Swinnen, Johan V.; Vinckier, Stefan; Soengas, María S.; Carmeliet, Peter; Noël, Agnès; Agostinis, Patrizia[et al.] (SpringerNature, 2022-05-19)Autophagy has vasculoprotective roles, but whether and how it regulates lymphatic endothelial cells (LEC) homeostasis and lymphangiogenesis is unknown. Here, we show that genetic deficiency of autophagy in LEC impairs ... -
Metabolic Reprogramming in Tumor Endothelial Cells.
García-Caballero, Melissa; Sokol, Liliana; Cuypers, Anne; Carmeliet, Peter (MDPI, 2022-09-21)The dynamic crosstalk between the different components of the tumor microenvironment is critical to determine cancer progression, metastatic dissemination, tumor immunity, and therapeutic responses. Angiogenesis is critical ... -
Role and therapeutic potential of dietary ketone bodies in lymph vessel growth.
García-Caballero, Melissa; Zecchin, Annalisa; Souffreau, Joris; Khanh Truong, Anh-Co; Teuwen, Laure-Anne; Vermaelen, Wesley; Martín-Pérez, Rosa; de Zeeuw, Pauline; Bouché, Ann; Vinckier, Stefan; Cornelissen, Ivo; Eelen, Guy; Ghesquière, Bart; Mazzone, Massimiliano; Dewerchin, Mieke; Carmeliet, Peter[et al.] (Nature, 2019-07-19)Los vasos linfáticos (LV), revestidos por células endoteliales linfáticas (LEC), son indispensables para la vida1. Sin embargo, el papel del metabolismo en las LEC no se ha dilucidado por completo. En el presente estudio, ... -
The role of fatty acid β-oxidation in lymphangiogenesis.
W Wong, Brian; Wang, Xingwu; Zecchin, Annalisa; Thienpont, Bernard; Cornelissen, Ivo; Kalucka, Joanna; García-Caballero, Melissa; Missiaen, Rindert; Huang, Hongling; Brüning, Ulrike; Blacher, Silvia; Vinckier, Stefan; Goveia, Jermaine; Knobloch, Marlen; Zhao, Hui; Dierkes, Cathrin; Shi, Chenyan; Hägerling, René; Moral-Dardé, Veronica; Wyns, Sabine; Lippens, Martin; Jessberger, Sebastian; Fendt, Sarah-Maria; Luttun, Aernout; Noel, Agnès; Kiefer, Friedemann; Ghesquière, Bart; Moons, Lieve; Schoonjans, Luc; Dewerchin, Mieke; Eelen, Guy; Lambrechts, Diether; Carmeliet, Peter[et al.] (Nature, 2017-02-02)Los vasos linfáticos están revestidos por células endoteliales linfáticas (LEC) y son fundamentales para la salud. Sin embargo, aún no se ha dilucidado el papel del metabolismo en el desarrollo linfático. En este trabajo ...