Listar por autor "Fuente-Martín, Esther"
Mostrando ítems 1-2 de 2
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LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus
Cobo-Vuilleumier, Nadia; Lorenzo, Petra I; García Rodríguez, Noelia; Herrera Gómez, Irene de Gracia; Fuente-Martin, Esther; López-Noriega, Livia; Mellado-Gil, José Manuel; Romero-Zerbo, Silvana Yanina
; Baquié, Mathurin; Lachaud, Christian Claude; Stifter, Katja; Perdomo, German; Bugliani, Marco; De Tata, Vincenzo; Bosco, Domenico; Parnaud, Geraldine; Pozo, David; Hmadcha, Abdelkrim; Florido, Javier P; Toscano, Miguel G; de Haan, Peter; Schoonjans, Kristina; Sánchez Palazón, Luis; Marchetti, Piero; Schirmbeck, Reinhold; Martín-Montalvo, Alejandro; Meda, Paolo; Bernat, Soria; Bermúdez Silva, Francisco Javier; St-Onge, Luc; Gauthier, Benoit R[et al.] (Nature Research, 2018)
Type 1 diabetes mellitus (T1DM) is due to the selective destruction of islet beta cells by immune cells. Current therapies focused on repressing the immune attack or stimulating beta cell regeneration still have limited ... -
The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity
(Springer Nature, 2018)HMG20A (also known as iBRAF) is a chromatin factor involved in neuronal differentiation and maturation. Recently small nucleotide polymorphisms (SNPs) in the HMG20A gene have been linked to type 2 diabetes mellitus (T2DM) ...