Listar por autor "García-Martín, María Luisa"
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Aproximaciones metabolómica y transcriptómica a la gestión del metabolismo en las acículas de Pinus pinaster L. aiton
Cañas-Pendon, Rafael Antonio
; Canales, Javier; Muñoz, Carmen; Granados, Jose M.; Pascual-Moreno, Maria Belen; Avila-Saez, Concepcion; García-Martín, María Luisa; Canovas-Ramos, Francisco Miguel[et al.] (2014-07-14)
Aproximaciones metabolómica y transcriptómica a la gestión del metabolismo en las acículas de Pinus pinaster L. Aiton Rafael A. Cañas1, Javier Canales1, Carmen Muñoz2, Jose M. Granados1, Ma Belén Pascual1, Concepción ... -
Bone marrow-derived mesenchymal stem cells transplantation produces a tissue recovery in hydrocephalic mice
García-Bonilla, María; Shumilov, Kirill; Vitorica, Javier; García-Martín, María Luisa; Muñoz, Carmen; Claros-Gil, Silvia; Gutierrez-Perez, Antonia; Jimenez-Lara, Antonio Jesus[et al.] (2018-07-25)
In congenital hydrocephalus, cerebrospinal fluid accumulation is associated to ischemia/hypoxia, metabolic impairment, neuronal damage and astrocytic reaction, which cause significant mortality and life-long neurological ... -
Brain tissue recovery in obstructive congenital hydrocephalus after intraventricular transplantation of mesenchymal stem cells
García-Bonilla, María; Ojeda-Pérez, Betsaida; Shumilov, Kirill; Vitorica, J.; García-Martín, María Luisa; Muñoz, Carmen; Gutierrez-Perez, Antonia; Jimenez-Lara, Antonio Jesus; Paez-Gonzalez, Patricia[et al.] (2018-10-29)
Introduction: Bone marrow-derived mesenchymal stem cells (BM-MSC) are a potential therapeutic tool due to their ability for migrating and producing neuroprotector factors when transplanted. The aim of this study was to ... -
Caracterización anual del metabolismo de las acículas de Pinus pinaster (Aiton) mediante procedimientos transcriptómicos y metabolómicos
Cañas-Pendon, Rafael Antonio; Canales, Javier; Muñoz, C.; Avila-Saez, Concepcion; García-Martín, María Luisa; Canovas-Ramos, Francisco Miguel[et al.] (2013-11-04)
El presente trabajo pretende iniciar una serie de estudios sobre el metabolismo nitrogenado en árboles adultos de la conífera Pinus pinaster (Aiton) en condiciones naturales. Durante un año completo se ha caracterizado ... -
Effect of bone marrow-derived mesenchymal stem cells on congenital hydrocephalus in the hyh mouse
García-Bonilla, María; Shumilov, Kirill; Vitorica, Javier; García-Martín, María Luisa; Muñoz, Carmen; Jimenez, Sebastian; Navarro, Victoria; García-Cuervo, Luisa; Cifuentes-Rueda, Manuel; Claros-Gil, Silvia; Andrades-Gomez, Jose Antonio; Guitérrez, Antonia; Paez-Gonzalez, Patricia; Jimenez-Lara, Antonio Jesus[et al.] (2017-06-28)
Background Bone marrow-derived mesenchymal stem cells (BM-MSC) are considered as a potential therapeutic tool for neurodegenerative diseases due to their ability for migrating into damaged tissue. Additionally, these cells ... -
Metabolite fingerprint detected with HR-MAS spectroscopy in ex vivo samples of cases with congenital hydrocephalus
Jimenez-Lara, Antonio Jesus; García-Martín, María Luisa; Muñoz, Carmen; Domínguez-Pinos, Dolores; Martinez-Leon, Maria Isabel; Gutierrez-Perez, Antonia; Pérez-Fígares, José Manuel[et al.] (2014-07-16)
Background: Changes in the profile of metabolites in brain and/or fluids can be useful to evaluate the severity and evolution of hydrocephalus, and consequently to help in treatment decisions. Magnetic Resonance Spectroscopy ... -
A metabolite profile reveals the presence of neurodegenerative conditions according to severity of hydrocephalus
García-Bonilla, María; Shumilov, Kirill; García-Martín, María Luisa; Muñoz, María Carmen; Domínguez-Pinos, Dolores; Gutierrez-Perez, Antonia; Paez-Gonzalez, Patricia; Jimenez-Lara, Antonio Jesus[et al.] (2018-11-29)
Introduction: In obstructive congenital hydrocephalus, cerebrospinal fluid accumulation is associated with high intracranial pressure (ICP), ischemia/hypoxia, metabolic impairment, neuronal damage and astrocytic reaction. ... -
Potential protective role of reactive astrocytes in the periventricular parenchyma in congenital hydrocephalus
García-Bonilla, María; Shumilov, Kirill; Peñalver, Ana; Castilla, Laura; Alonso-Carrión, Francisco José; Márquez-Gómez, Javier; García-Martín, María Luisa; Muñoz, Carmen; Gutierrez-Perez, Antonia; Jimenez-Lara, Antonio Jesus[et al.] (2016-07-11)
Background Cerebrospinal fluid accumulation in hydrocephalus produces an elevation of intraventricular pressure with pathological consequences on the periventricular brain parenchyma including ischemia, oedema, oxidative ... -
The synthetic molecule stauprimide impairs cell growth and migration in triple-negative breast cancer
Carrillo, P; Bernal, M; Téllez Quijorna, Clara; Marrero, A.D; Vidal, I; Castilla, L; Caro, C; Domínguez, A; García-Martín, M.L; Quesada, A.R.; Medina, M.A; Martinez-Poveda, Beatriz Amparo[et al.] (Elsevier, 2022-12-14)
Stauprimide, a semi-synthetic derivative of staurosporine, is known mainly for its potent differentiation-enhancing properties in embryonic stem cells. Here, we studied the effects of stauprimide in cell growth and migration ...