- RIUMA Principal
- Listar por autor
Listar por autor "Rodriguez-Ortiz, Carlos"
Mostrando ítems 1-3 de 3
-
Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology.
Baglietto-Vargas, David; Forner, Stefania; Cai, Lena; Martini, Alessandra C; Trujillo-Estrada, Laura; Swarup, Vivek; Minh Thu Nguyen, Marie; Do Huynh, Kelly; Javonillo, Dominic I; Minh Tran, Kristine; Phan, Jimmy; Jiang, Shan; Kramár, Enikö A; Nuñez-Diaz, Cristina; Balderrama-Gutierrez, Gabriela; Garcia, Franklin; Childs, Jessica; Rodriguez-Ortiz, Carlos J; Garcia-Leon, Juan Antonio; Kitazawa, Masashi; Shahnawaz, Mohammad; Matheos, Dina P; Ma, Xinyi; Da Cunha, Celia; Walls, Ken C; Ager, Rahasson R; Soto, Claudio; Gutierrez, Antonia; Moreno-Gonzalez, Ines; Mortazavi, Ali; Tenner, Andrea J; MacGregor, Grant R; Wood, Marcelo; Green, Kim N; LaFerla, Frank M[et al.] (Springer Nature, 2021-04-23)The majority of Alzheimer’s disease (AD) cases are late-onset and occur sporadically, however most mouse models of the disease harbor pathogenic mutations, rendering them better representations of familial autosomal-dominant ... -
Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease.
Baglietto-Vargas, David; Aleph Prieto, Gilberto; Limon, Agenor; Forner, Stefania; Rodriguez-Ortiz, Carlos J; Ikemura, Kenji; Ager, Rahasson R; Medeiros, Rodrigo; Trujillo-Estrada, Laura; Martini, Alessandra C; Kitazawa, Masashi; Davila, Jose C; Cotman, Carl W; Gutierrez, Antonia; LaFerla, Frank M[et al.] (Wiley, 2018-08-17)Alzheimer's disease (AD) is a devastating neurodegenerative disorder that impairs memory and causes cognitive and psychiatric deficits. New evidences indicate that AD is conceptualized as a disease of synaptic failure, ... -
miR-181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer's disease.
Rodriguez-Ortiz, Carlos; Prieto, Gilberto Aleph; Martini, Alessandra; Forner, Stefania; Trujillo-Estrada, Laura Isabel; LaFerla, Frank M.; Baglietto-Vargas, David; Cotman, Carl; Kitazawa, Masashi[et al.] (Wiley, 2020-02-22)MicroRNAs play a pivotal role in rapid, dynamic, and spatiotemporal modulation ofsynaptic functions. Among them, recent emerging evidence highlights that micro-RNA-181a (miR-181a) is particularly abundant in hippocampal ...