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A bottom-up characterization of transfer functions for synthetic biology designs: lessons from enzymology
Carbonell-Ballesteros, Max; Durán-Nebreda, Salva; Montañez, Raúl; Macía, Javier; Rodríguez-Caso, Carlos Francisco (Oxfrod University Press, 2014-12-16)Within the field of synthetic biology, a rational design of genetic parts should include a causal understanding of their input-output responses-the so-called transfer function-and how to tune them. However, a commonly ... -
Dealing with the genetic load in bacterial synthetic biology circuits: convergences with the Ohm's law.
Carbonell-Ballesteros, Max; García-Ramallo, Eva; Montañez, Raúl; Rodríguez-Caso, Carlos Francisco; Macía, Javier (2015)Synthetic biology seeks to envision living cells as a matter of engineering. However, increasing evidence suggests that the genetic load imposed by the incorporation of synthetic devices in a living organism introduces a ...