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Listar por autor "Fernández, Mariana"
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Assessment of estrogenic and anti-androgenic activities of the mycotoxin zearalenone and its metabolites using in vitro receptor-specific bioassays
Molina-Molina, José-Manuel; Real-Domínguez, María Macarena; Jimenez-Diaz, Inmaculada; Belhassen, Hidaya; Hedhili, Abderazzak; Torné, Pablo; Fernández, Mariana; Olea, Nicolás[et al.] (Elsevier, 2014)Zearalenone (ZEN) is a well-known mycotoxin present in numerous agricultural products. Humans and animals are therefore at a risk of exposure to zearalenone through consumption of contaminated food. After intake, ZEN is ... -
Assessment of hormone-like activities in Ginkgo biloba, Elettaria cardamomum and Plantago ovata extracts using in vitro receptor-specific bioassays
Real-Domínguez, María Macarena; Molina-Molina, José-Manuel; Jimenez, Jesús; Diéguez, Horacio R.; Fernández, Mariana; Olea, Nicolás[et al.] (Taylor & Francis, 2015)Medicinal plants are widely used for the treatment of diseases and for the development of new drugs. This study was designed to determine the presence of hormone-like activities dependent on the activation of human estrogen ... -
Human adipose tissue levels of persistent organic pollutants and metabolic syndrome components: combining a cross-sectional with a 10-year longitudinal study using a multi-pollutant approach
Mustieles, Vicente; Fernandez, Mariana; Martin-Olmedo, Piedad; Gonzalez Alzaga, Beatriz; Fontalba-Navas, Andrés; Hauser, Russ; Olea, Nicolás; Arrebola, Juan Pedro[et al.] (Elsevier, 2017)We aimed to assess the influence of long-term exposure to POPs on the risk of metabolic syndrome, combining a cross-sectional with a 10-year longitudinal follow-up design. Residues of eight POPs were quantified in adipose ... -
In vitro study on the agonistic and antagonistic activities of bisphenol-S and other bisphenol-A congeners and derivatives via nuclear receptors
Molina-Molina, José-Manuel; Amaya, Esperanza; Grimaldi, Marina; Sáenz, José-María; Real-Domínguez, María Macarena; Fernández, Mariana; Balaguer, Patrick; Olea, Nicolás[et al.] (Elsevier, 2013)Bisphenols are a group of chemicals structurally similar to bisphenol-A (BPA) in current use as the primary raw material in the production of polycarbonate and epoxy resins. Some bisphenols are intended to replace BPA in ... -
Screening of hormone-like activities in bottled waters available in Southern Spain using receptor-specific bioassays
Real-Domínguez, María Macarena; Molina-Molina, José-Manuel; Jiménez-Díaz, Inmaculada; Arrebola, Juan Pedro; Sáenz, José-María; Fernández, Mariana; Olea, Nicolás[et al.] (Elsevier, 2015)Bottled water consumption is a putative source of human exposure to endocrine-disrupting chemicals (EDCs). Research has been conducted on the presence of chemicals with estrogen-like activity in bottled waters and on their ... -
Simultaneous determination of the UV-filters benzyl salicylate, phenyl salicylate, octyl salicylate, homosalate, 3-(4-methylbenzylidene) camphor and 3-benzylidene camphor in human placental tissue by LC–MS/MS. Assessment of their in vitro endocrine activity
Jiménez-Díaz, Inmaculada; Molina-Molina, José Manuel; Zafra-Gómez, Alberto; Ballesteros, Oscar; Navalón, Alberto; Real-Domínguez, María Macarena; Sáenz, José Maria; Fernández, Mariana; Olea, Nicolás[et al.] (Elsevier, 2013-10)UV-filters are widely used in many personal care products and cosmetics. Recent studies indicate that some organic UV-filters can accumulate in biota and act as endocrine disruptors, but there are few studies on the ...