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Listar por autor "Céspedes Lagos, José Antonio"
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Advances and highlights in T and B cell responses to drug antigens
Fernández-Santamaría, Rubén; Ariza Veguillas, Adriana; Fernández-Duarte, Tahía Diana; Céspedes Lagos, José Antonio; Labella, Marina; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa[et al.] (Wiley, 2021-10-07)The immunological mechanisms involved in drug hypersensitivity reactions (DHRs) are complex, and despite important advances, multiple aspects remain poorly understood. These not fully known aspects are mainly related to ... -
Dendrímeros antigénicos sobre partículas de sílica para determinar IgE específicas de antibióticos betalactámicos
Matamoros Castellano, Esther; Jiménez, Isabel M.; Gil-Ocaña, Violeta; Mayorga Mayorga, Cristobalina; Doña, Inmaculada; Céspedes Lagos, José Antonio; Montañez-Vega, María Isabel; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel; Torres-Cazorla, María Isabel[et al.] (2022)Los inmunoensayos empleados para el diagnóstico in vitro de alergias a antibióticos betalactámicos actualmente presentan una limitada sensibilidad y pobre especificidad, además de no estar disponibles de forma comercial ... -
Diagnosis of immediate reactions to amoxicillin: Comparison of basophil activation markers CD63 and CD203c in a prospective study
Céspedes Lagos, José Antonio; Fernández-Santamaría, Rubén; Ariza Veguillas, Adriana; Bogas Herrera, Gádor; Doña, Inmaculada; Rondón, Carmen; Salas, María; Labella, Marina; Frecha, Cecilia; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Fernández-Duarte, Tahía Diana[et al.] (Wiley, 2022-12-07)Amoxicillin (AX) combined or not with clavulanic acid (CLV) is frequently involved in IgE-mediated reactions. Drug provocation test (DPT) is considered as the gold standard for diagnosis, although contraindicated in high-risk ... -
In vitro supporting diagnostic tools in plant‐food allergy.
Céspedes Lagos, José Antonio; Lebrón-Martín, Clara; García-Otón, Reyes; Delgado, María Jesús; Martín Astorga, María del Carmen; Pérez-Sánchez, Natalia Isabel; Gómez, Francisca; Torres-Jaén, María Josefa; Cañas, José Antonio; Aranda, Carlos José; Mayorga Mayorga, Cristobalina[et al.] (Wiley, 2023-04-06) -
LPS in combination with amoxicillin increases BAT sensitivity to amoxicillin IgE‐mediated hypersensitivity
Céspedes Lagos, José Antonio; Fernández-Santamaría, Rubén; Bogas Herrera, Gádor; Ariza Veguillas, Adriana; Doña, Inmaculada; Salas, María; Labella, Marina; Fernández-Duarte, Tahía Diana; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Frecha, Cecilia[et al.] (Wiley, 2024)β-lactams (BLs), and among them, amoxicillin (AX) are the most current prescribed antibiotics to treat bacterial infections,1 and their use is related to an increasing prevalence of drug hypersensitivity reactions (DHRs),2 ... -
Silica Particle based nanocomposites for Specific IgE Determination to Betalactams
Matamoros Castellano, Esther; Gil-Ocaña, Violeta; Jiménez, Isabel M.; Mayorga Mayorga, Cristobalina; Doña, Inmaculada; Céspedes Lagos, José Antonio; Montañez-Vega, María Isabel; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel; Torres-Jaén, María Josefa[et al.] (2023)Current immunoassays for diagnosing betalactam (BL) allergy have limited sensitivity and poor specificity. These include ImmunoCAP, the commercial immunoassay, and the radioallergosorbent test (RAST), a handmade test ... -
Synthetic antigenic determinants of clavulanic acid induce dendritic cell maturation and specific T cell proliferation in patients with immediate hypersensitivity reactions
Fernández-Santamaría, Rubén; Bogas Herrera, Gádor; Montañez-Vega, María Isabel; Ariza Veguillas, Adriana; Salas, María; Céspedes Lagos, José Antonio; Labella, Marina; Paris, Juan Luis; Pérez-Sánchez, Natalia Isabel; Pérez-de-Inestrosa-Villatoro, Ezequiel; Vida-Pol, Yolanda; Fernández-Duarte, Tahía Diana; Mayorga Mayorga, Cristobalina[et al.] (Wiley, 2022-05-24)Background Immediate drug hypersensitivity reactions (IDHRs) to clavulanic acid (CLV) have increased in the last decades due to a higher consumption alongside amoxicillin (AX). Due to its chemical instability, diagnostic ... -
The value of the basophil activation test in the evaluation of patients reporting allergic reactions to the BNT162b2 mRNA COVID-19 vaccine
Labella, Marina; Céspedes Lagos, José Antonio; Doña, Inmaculada; Shamji, Mohamed H.; Agache, Ioana; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa[et al.] (Wiley, 2021-10-24)