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An Efficient Machine Learning Method to Identify Genetic Drivers of Avian Influenza Virus Adaptation to Humans
Leiva Rebollo, Rocío; Patiño Galindo, Juan; Villalon Letelier, Fernando; Mena, Nacho; Tansey, W; Park, K; Labella Vera, Alejandro Manuel; Castro-López, María Dolores; Borrego-García, Juan José; Rabadán, Raúl; García Sastre, Adolfo[et al.] (2024-09-02)In this work we developed a method, based on a logistic regression model, to identify mutations subject to directional selection. We tested the model analyzing thousands of AIV (H5N1, H7N9) sequences from public datasets, ...